The benefits and effects of CBD have not even been comprehensively studied yet, and already there are countless positive effects to using it. While there are innumerable studies still underway, we have determined that CBD is known to directly or indirectly affect these receptors:
Serotonin, which is used for stress management and mood management.
Adenosine, which is important for sleep-wake and your circadian rhythm.
Vanilloid, which is important for pain modulation and management.
All of these are incredibly important receptors to manage for small-scale everyday life to large-scale ailments such as cancer and diabetes. These are just a few of the effects that have been confirmed to be altered by regular use of CBD, others are still being studied at the time of writing.
Are there any Negative Effects of CBD?
As of right now, there are no 'confirmed' negative effects of CBD. However, one has been contested and is currently still up for debate.
In a rodent case study of CBD, there were signs that the rodents were having a fatty acid chain known as FAAH being blocked. This would slow down the bodies natural breakdown of endocannabinoid anandamide in the body.
This is important because it is known as the bliss molecule, or human manufactured THC. It regulates your functions like pleasure and reward, appetite, memory, sleep and pain. Affecting this, in the long run, can create crashes similar to how the body feels when you binge caffeine or nicotine without properly de-escalating your body back down. While this isn't fatal, it can affect the bodies ability to regulate if not used responsibly.
However, a study that was published in 2015 suggested (an overall positive orientation) that CBD does NOT inhibit FAAH in humans. Instead, the study found that the compound engages in proteins that bind the anandamide to FAAH and not the bodies process itself.
The only fact is that CBD has an effect on the bliss molecule of the body and is regularly being tested at the time of writing to determine how and in what way.
Despite being heavily studied, it is still being used to aid treatment in multiple major diseases from Cancer to Lupus, read more about What is CBD Used to Treat?
Additionally, three major conditions have been proved to be positively affected by CBD: Anxiety, Schizophrenia, and Epilepsy. Read more about these Major Conditions Helped by CBD