Hereditary hemorrhagic telangiectasia (Osler Weber Rendu syndrome)

About Hereditary hemorrhagic telangiectasia (Osler Weber Rendu syndrome)

An inherited disease of blood vessels which causes excessive bleeding. Patients develop red or reddish-purple collections of abnormal blood vessels called telangiectases or arterio-venous malformations (AVMs). Patients experience bleeding episodes from the nose, gastrointestinal tract and the brain.

Symptoms

Nosebleeds, vomiting blood, rectal bleeding, discoloration of the skin, headaches, seizures, confusion.

Tests & Diagnostics

A history and physical exam will be performed. Genetic testing can be performed.

Conventional treatment summary

Estrogen may decrease the number of telangiectasias. Bleeding is stopped with cautery, but in severe cases, surgery or embolization of the artery may be recommended.

Medical specialties

Hematology and Oncology · Pediatric Hematology and Oncology

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Hereditary hemorrhagic telangiectasia (Osler Weber Rendu syndrome).