Polycythemia vera (increased blood cells)
About Polycythemia vera (increased blood cells)
Overproduction of red blood cells in the bone marrow. The blood is more prone to form clots (thrombosis) in the arteries, and this can cause complications like stroke or kidney failure. Polycythemia vera occurs because cells in the bone marrow have developed a gene mutation. Polycythemia vera can develop into leukemia. Death can occur from thrombosis, leukemia or bleeding.Symptoms
Breathing difficulty when lying down, dizziness, fullness in the left upper abdomen, headache, itchiness, especially following a warm bath, red coloration, especially of the face, shortness of breath, symptoms of phlebitis.Tests & Diagnostics
A history and physical exam will be performed. A complete blood count (CBC) blood test suggests the diagnosis. Other tests to establish the diagnosis include: bone marrow biopsy.Common tests: Complete blood count (CBC), Comprehensive metabolic panel (CMP).
Conventional treatment summary
Blood draws (removal of blood, as would be done in a blood donation) are used to decrease the risk for clotting. The medication hydroxyurea may be used to suppress the bone marrow. Interferon and anagrelide may be given to lower the blood and platelet counts.Medical specialties
Internal Medicine · Hematology and Oncology · Pediatric Hematology and Oncology
This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Polycythemia vera (increased blood cells).