Henoch Schönlein purpura

About Henoch Schönlein purpura

A disease in which small blood vessels become inflamed (vasculitis) which causes purple spots on the skin (purpura). Other symptoms include: joint pain, vomiting, abdominal pain, diarrhea, and inflammation of the kidneys (glomerulonephritis). It is more common in children than adults. The cause of the disease is unknown. It is characterized by an abnormal immune response. A serious intestinal disorder called intussusception can be associated with this disorder.

Symptoms

Abdominal pain, black or bloody stools, vomiting. diarrhea, joint pain, purple spots on the skin (purpura).

Tests & Diagnostics

A history and physical exam will be performed. Tests to determine the severity of the disease will be performed, often including blood and urine tests, abdominal CT scan and, in some cases a skin and/or kidney biopsy..

Common tests: Complete blood count (CBC), Comprehensive metabolic panel (CMP), Urinalysis (UA).

Conventional treatment summary

Supportive treatment is provided, including intravenous fluids and, if necessary, blood transfusions. Occasionally the following treatments are administered: steroids, nonsteroidal anti-inflammatory medications/NSAIDs (ibuprofen/Motrin or Advil, naproxen/Naprosyn), acetaminophen (Tylenol), dapsone, azathioprine, intravenous immunoglobulin, and plasmapheresis.

Medical specialties

Hematology and Oncology · Pediatric Hematology and Oncology

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Henoch Schönlein purpura.