Calcium channel blocker overdose
About Calcium channel blocker overdose
Calcium channel blockers are blood pressure medications. Overdoses can occur accidentally or intentionally, Severe overdoses can result in very low blood pressure, slow heart rates and death. Common drugs in this class are: Amlodipine (Norvasc), Diltiazem (Cardizem, Dilacor), Nifedipine (Adalat, Procardia), Verapamil (Calan, Isoptin, Verelan). Accidental ingestion of even one pill in an infant can by very serious and lead to death requiring immediate medical attention.Symptoms
Confusion, low blood pressure, slow heart rate, fainting, nausea, weakness, drowsiness, breathing problems, coma, seizure, death.Tests & Diagnostics
A history and physical exam will be performed. Tests are done to identify the organ damage done by the overdose, and to rule out other causes of the symptoms. The diagnosis is made through the history since blood levels may not be readily available.Common tests: BHCG, Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, EKG, Troponin, Urinalysis (UA), X-ray.
Conventional treatment summary
Depending on the severity of symptoms, treatment may include Intravenous fluids, glucagon, glucose, insulin and calcium infusions. Intubation and medications to raise the blood pressure (such as norepinephrine) may be necessary. For more information and help call your local poison center at 1-800-222-1222.Medical specialties
Medical Toxicology
This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Calcium channel blocker overdose.