Serum sickness
About Serum sickness
A disorder that is similar to an allergic reaction that causes fever, rash and arthritis. Unlike a typical allergic reaction the symptoms do not appear until 7-10 days after exposure to a medication or an antiserum. The most common implicated medications include: cephalosporins, penicillins, or sulfa.Symptoms
Fever, hives, joint pain, vomiting, rash, swollen lymph nodes.Tests & Diagnostics
A history and physical exam will be performed. Tests to rule out other causes of the symptoms are typically performed.Common tests: Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, EKG, Urinalysis (UA), X-ray.
OTC sleep aids and supportive treatments
Prescription medications
Conventional treatment summary
Therapy depends on the severity of the disease. Treatment may include: antihistamines, steroids, and/or nonsteroidal anti-inflammatory medications/NSAIDs (ibuprofen/Motrin or Advil, naproxen/Naprosyn). Pain medications such as acetaminophen (Tylenol). The offending agent must be stopped. Consider calling the National Poison Control Phone Number for further information or assistance: 1-800-222-1222.Medical specialties
Medical Toxicology
This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Serum sickness.