Gout (uric acid crystals in the joint causing inflammation)

About Gout (uric acid crystals in the joint causing inflammation)

Occurs when there is an imbalance between the production and excretion of uric acid. Uric acid crystals accumulate in the joints leading to acute inflammation. The attacks are usually recurrent and most commonly affect the great toe, foot, ankle, knee, and hand. The pain can be severe, increasing with even the slightest touch of the affected joint.

Symptoms

Pain, swelling, redness, and increased warmth of the affected joint.

Tests & Diagnostics

A history and physical exam will be performed. The diagnosis is made by obtaining joint fluid using a needle (arthrocentesis) and examining the fluid for uric acid crystals. Blood testing to measure uric acid and x-rays may be recommended. However, testing may not be necessary to diagnose gout.

Common tests: Complete blood count (CBC), X-ray.

Path 3 — Prescription Options

Prescription medications

Conventional treatment summary

Treatment includes: rest, nonsteroidal anti-inflammatory medications/NSAIDs (indomethacin/Indocin, ibuprofen/Motrin), colchicine, pain medications such as acetaminophen (Tylenol), and/or steroids. Later, after an acute attack has subsided, the following medications and behavioral modifications may reduce the number of attacks: probenecid (Benuryl), allopurinol (Zyloprim), febuxostat (Uloric), cessation of alcohol use (especially beer), and decreased the consumption of red meat and seafood.

Medical specialties

Internal Medicine · Orthopedic Surgery · Rheumatology · Family Practice · Pediatric Rheumatology · Podiatry · Foot and Ankle Surgery

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Gout (uric acid crystals in the joint causing inflammation).