Hyperemesis gravidarum (severe vomiting in pregnancy)

About Hyperemesis gravidarum (severe vomiting in pregnancy)

Severe nausea and vomiting during pregnancy and most often occurring during the first trimester. It can cause dehydration and drastic changes in body chemistry, and may be dangerous to the mother and baby. The exact cause is unknown but risk factors include: first pregnancy, hyper-emesis gravidarum during a previous pregnancy, having a multiple pregnancy (such as twins or triplets), and being overweight, The disorder occurs in about 0.5 to 2% of all pregnancies.

Symptoms

Vomiting, nausea, fatigue, weight loss, decreased urination, confusion, lightheadedness, fainting.

Tests & Diagnostics

A history and physical exam will be performed. Blood and urine tests may be done to measure the extent of dehydration, electrolyte abnormalities and to rule out an infection or other explanation for the symptoms.

Common tests: Comprehensive metabolic panel (CMP), Urinalysis (UA).

Path 3 — Prescription Options

Prescription medications

Conventional treatment summary

Treatment includes: oral or intravenous fluids and anti-nausea medications. Frequent, small meals and vitamin B6 (up to 100 mg/day) may be helpful. Over time, this condition usually improves on its own.

Medical specialties

Obstetrics and Gynecology

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Hyperemesis gravidarum (severe vomiting in pregnancy).