Erythema nodosum
About Erythema nodosum
Erythema nodosum is a raised, red, bumpy rash that usually involves the front of the lower legs. It is often associated with certain infections (tuberculosis, yersinia, salmonella, campylobacter, streptococcus), drugs (birth control pills, sulfa medications, estrogens) and diseases (sarcoidosis, Crohn's disease, ulcerative colitis). At times no cause is determined (idiopathic). Most cases resolve within eight weeks. Women are affected more often than men and it occurs most frequently in patients between the ages of 18 and 34.Symptoms
Fever, flu-like symptoms, pain and a red rash on the front of the lower legs. The rash consists of red raised bumps.Tests & Diagnostics
A history and physical will be performed. The diagnosis can usually be made on exam. Laboratory and imaging studies may be performed to look for associated diseases. Occasionally, a skin biopsy may be required to confirm the diagnosis.Common tests: Blood culture, Complete blood count (CBC), ESR, Rapid strep Test, Skin biopsy, Stool culture, TB Test, Chest X-ray.
OTC sleep aids and supportive treatments
Prescription medications
Conventional treatment summary
Erythema nodosum often resolves on it's own and treatment is directed at symptomatic relief. Anti-inflammatory medications, limb elevation and cool compresses are frequently used. Associated infections or systemic infections are treated separately.Medical specialties
Internal Medicine · Dermatology · Pediatrics · Family Practice
This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Erythema nodosum.