Hemolytic uremic syndrome (HUS)

About Hemolytic uremic syndrome (HUS)

A condition affecting the kidneys following destruction of red blood cells from a gastrointestinal infection caused by E. coli bacteria. The salmonella and shigella bacteria have also been implicated in this syndrome. This condition most commonly affects children resulting in the most common cause of acute kidney failure in this age group.

Symptoms

Blood in stools, vomiting, diarrhea, fever, weakness, decreased urine output, and confusion

Tests & Diagnostics

A history and physical will be performed. Blood and urine samples will be obtained to evaluate kidney function, red blood cells, white blood cells, platelets and the chemical balance of the blood (electrolytes). A kidney biopsy may be done.

Common tests: Complete blood count (CBC), Comprehensive metabolic panel (CMP), Partial throboplastin time (PTT), Protime, Stool culture, Urinalysis (UA).

Conventional treatment summary

Therapy depends on the severity of the illness. Patients with serious symptoms or kidney damage may receive intravenous (IV) fluids, dialysis, and/or plasmapheresis (plasma exchange).

Medical specialties

Pediatrics · Nephrology · Family Practice · Pediatric Nephrology

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Hemolytic uremic syndrome (HUS).