Toxemia of pregnancy (preeclampsia)

About Toxemia of pregnancy (preeclampsia)

Preeclampsia (toxemia) is a condition of pregnancy marked by high blood pressure, protein in the urine, and swelling of the feet and hands. Women with eclampsia have the same signs and symptoms and in addition have one or more seizures. . Preeclampsia and eclampsia is seen after the 20th week of pregnancy. The following increase the risk of having preeclampsia and eclampsia: teenage pregnancy, previous history of preeclampsia, obesity, carrying more than one baby (twins, triplets etc.), having high blood pressure, mother's age greater than 35, and being of African American descent. This condition is very serious requiring immediate treatment.

Symptoms

Headache, upper abdominal pain, blurred vision, nausea, vomiting, leg swelling, hand swelling, sudden weight gain.

Tests & Diagnostics

A history and physical exam will be performed. The urine is checked for protein. Blood tests are done to identify high uric acid, elevated liver function tests, low platelets and renal failure.

Common tests: Complete blood count (CBC), Comprehensive metabolic panel (CMP), Urinalysis (UA), Ultrasound.

Conventional treatment summary

Treatment includes: intravenous magnesium, aggressive blood pressure control with medications (hydralazine, labetalol), and possibly antiseizure medications. Definitive treatment is delivery of the baby.

Medical specialties

Obstetrics and Gynecology

This page is educational content, not medical advice. Always consult a qualified clinician for diagnosis and treatment of Toxemia of pregnancy (preeclampsia).