Aliskiren
Why this is used
Aliskiren is used alone or in combination with other medications to treat high blood pressure. Aliskiren is in a class of medications called direct renin inhibitors. It works by decreasing certain natural chemicals that tighten the blood vessels, so blood vessels relax and the heart can pump blood more efficiently.
How to take it
Aliskiren comes as a tablet to take by mouth. It is usually taken once a day. Aliskiren should be taken the same way each time, either always with food or always without food. Take aliskiren at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take aliskiren exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on an low dose of aliskiren and may increase your dose after you have been taking this medication for at least two weeks. Aliskiren controls high blood pressure but does not cure it. Continue to take aliskiren even if you feel well. Do not stop taking aliskiren without talking to your doctor. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Side effects
<p></p> <p></p> <p></p> <p>Aliskiren may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
diarrhea</li>
<li>
stomach pain</li>
<li>
heartburn</li>
<li>
cough</li>
<li>
rash</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
<ul>
<li>
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs</li>
<li>
hoarseness</li>
<li>
difficulty swallowing or breathing</li>
<li>
lightheadedness</li>
<li>
fainting</li></ul>Aliskiren may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.</p>
<ul>
<li>
diarrhea</li>
<li>
stomach pain</li>
<li>
heartburn</li>
<li>
cough</li>
<li>
rash</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
<ul>
<li>
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs</li>
<li>
hoarseness</li>
<li>
difficulty swallowing or breathing</li>
<li>
lightheadedness</li>
<li>
fainting</li></ul>Aliskiren may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.</p>
Precautions
Before taking aliskiren, tell your doctor and pharmacist if you are allergic to aliskiren or any other medications. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); antifungals such as ketoconazole (Nizoral); atorvastatin (Lipitor); diuretics ('water pills') such as hydrochlorothiazide (HCTZ) and furosemide (Lasix); irbesartan (Avapro); and other medications for heart disease or high blood pressure. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had diabetes, seizures, or kidney disease. you should know that aliskiren may cause dizziness, lightheadedness, and fainting. Lie down if you feel faint or dizzy, and call your doctor right away.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:
<ul>
<li>
fainting</li>
<li>
dizziness</li>
<li>
blurred vision</li>
<li>
nausea</li></ul>
<ul>
<li>
fainting</li>
<li>
dizziness</li>
<li>
blurred vision</li>
<li>
nausea</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Aliskiren.