Alitretinoin
Why this is used
Alitretinoin is used to treat skin lesions associated with Kaposi's sarcoma. It helps stop the growth of Kaposi's sarcoma cells. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How to take it
Alitretinoin comes in topical gel. Alitretinoin is usually used twice a day. Your doctor may tell you to use alitretinoin more or less frequently depending on your response to it. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use alitretinoin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Alitretinoin controls Kaposi's sarcoma lesions but does not cure them. It will take at least 2 weeks of using alitretinoin before a benefit can be seen. For some patients, it may take 8-14 weeks to see results. Do not stop using alitretinoin without talking to your doctor. To apply alitretinoin, follow these steps:
<list list-type='ordered' numbering='arabic'>
<li>
Wash your hands and affected skin area thoroughly with mild soap (not medicated or abrasive soap or soap that dries the skin) and water.</li>
<li>
Use clean fingertips, a gauze pad, or a cotton swab to apply the medication.</li>
<li>
Apply enough gel to cover the lesion with a generous coating.</li>
<li>
Apply the medication to the affected skin area only. Do not apply to unaffected areas; do not apply on or near mucus membranes.</li>
<li>
Allow the gel to dry for 3-5 minutes before covering with clothing.</li></ul>
<list list-type='ordered' numbering='arabic'>
<li>
Wash your hands and affected skin area thoroughly with mild soap (not medicated or abrasive soap or soap that dries the skin) and water.</li>
<li>
Use clean fingertips, a gauze pad, or a cotton swab to apply the medication.</li>
<li>
Apply enough gel to cover the lesion with a generous coating.</li>
<li>
Apply the medication to the affected skin area only. Do not apply to unaffected areas; do not apply on or near mucus membranes.</li>
<li>
Allow the gel to dry for 3-5 minutes before covering with clothing.</li></ul>
Side effects
<p></p> <p></p> <p></p> <p>Alitretinoin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
warmth or slight stinging of the skin</li>
<li>
lightening or darkening of the skin</li>
<li>
red, scaling skin</li>
<li>
rash</li>
<li>
swelling, blistering, or crusting of the skin</li>
<li>
pain at site of application</li>
<li>
itching</li></ul></p> <p></p> <p></p>
<ul>
<li>
warmth or slight stinging of the skin</li>
<li>
lightening or darkening of the skin</li>
<li>
red, scaling skin</li>
<li>
rash</li>
<li>
swelling, blistering, or crusting of the skin</li>
<li>
pain at site of application</li>
<li>
itching</li></ul></p> <p></p> <p></p>
Precautions
Before using alitretinoin, tell your doctor and pharmacist if you are allergic to alitretinoin, etretinate, isotretinoin, tazarotene, tretinoin, or any other drugs. tell your doctor what other medications you are taking, including vitamins or herbal products. Do not use insect repellants that contain DEET while using alitretinoin. tell your doctor if you have or have ever had a type of skin cancer known as T-cell lymphoma. plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Alitretinoin may make your skin sensitive to sunlight.
Educational reference only — talk to a pharmacist or prescriber about Alitretinoin.