Benazepril and Hydrochlorothiazide

Why this is used

The combination of benazepril and hydrochlorothiazide is used to treat high blood pressure. Benazepril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly. Hydrochlorothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

How to take it

The combination of benazepril and hydrochlorothiazide comes as a tablet to take by mouth. It is usually taken once a day. To help you remember to take benazepril and hydrochlorothiazide, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take benazepril and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Benazepril and hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take benazepril and hydrochlorothiazide even if you feel well. Do not stop taking benazepril and hydrochlorothiazide without talking to your doctor.

Side effects

<p></p> <p></p> <p></p> <p>Benazepril and hydrochlorothiazide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

<ul>
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cough</li>
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dizziness</li>
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excessive tiredness</li>
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drowsiness</li></ul></p> <p></p> <p>Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

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swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs</li>
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hoarseness</li>
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difficulty breathing or swallowing</li>
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rash</li>
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lightheadedness</li>
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fainting</li>
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fever, sore throat, chills, and other signs of infection</li>
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yellowing of the skin or eyes</li>
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dry mouth</li>
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thirst</li>
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weakness</li>
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lack of energy</li>
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restlessness</li>
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muscle pains or cramps</li>
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infrequent urination</li>
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upset stomach</li>
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vomiting</li>
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rapid, pounding, or irregular heartbeat</li></ul>Benazepril and hydrochlorothiazide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before taking benazepril and hydrochlorothiazide, tell your doctor and pharmacist if you are allergic to benazepril (Lotensin), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), trandolapril (Mavik), sulfa drugs, or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cholestyramine (Questran); colestipol (Colestid); insulin; lithium (Eskalith, Lithobid); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); other diuretics ('water pills'); other medications for high blood pressure; and potassium supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have recently had severe diarrhea or vomiting and if you have or have ever had allergies; asthma; heart failure; diabetes; gout; high cholesterol; lupus; scleroderma; or kidney or liver disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking benazepril and hydrochlorothiazide. you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Benazepril and Hydrochlorothiazide.