Candesartan

Why this is used

Candesartan is used alone or in combination with other medications to treat high blood pressure. Candesartan is also used alone or in combination with other medications to treat congestive heart failure (a condition when your heart can not pump enough blood to the other parts of the body). Candesartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

How to take it

Candesartan comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take candesartan, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take candesartan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on a low dose of candesartan and gradually increase your dose not more than once every 2 weeks. Candesartan controls high blood pressure but does not cure it. Your blood pressure may decrease during the first 2 weeks of your treatment, but it may take 4 to 6 weeks for you to notice the full benefit of candesartan. Continue to take candesartan even if you feel well. Do not stop taking candesartan without talking to your doctor.

Side effects

<p></p> <p></p> <p></p> <p>Candesartan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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headache</li>
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dizziness</li>
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back pain</li>
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sore throat</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately:

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swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs</li>
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hoarseness</li>
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difficulty breathing or swallowing</li>
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decreased urination</li></ul>Candesartan may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before taking candesartan, tell your doctor and pharmacist if you are allergic to candesartan, any other medications, or any of the ingredients in candesartan tablets. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec, in Lexxel, in Vaseretic), fosinopril (Monopril), lisinopril (Prinivil, Zestril, in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril, (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), diuretics ('water pills') including spironolactone (Aldactone, in Aldactazide); lithium (Eskalith CR, Eskalith, Lithobid); medications for diabetes; other medications for high blood pressure;and potassium supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had heart, kidney, or liver disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking candesartan. you should know that candesartan may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking candesartan. To help void this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting. Tell your doctor if you have any of these problems or develop them during your treatment.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include the following:

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dizziness</li>
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fainting</li>
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fast or slow heart beat</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Candesartan.