Chlordiazepoxide
Why this is used
Chlordiazepoxide is used to relieve anxiety and to control agitation caused by alcohol withdrawal.
How to take it
Chlordiazepoxide comes as a tablet and capsule to take by mouth. It usually is taken one to four times a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take chlordiazepoxide exactly as directed. Chlordiazepoxide can be habit-forming. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tolerance may develop with long-term or excessive use, making the drug less effective. This medication must be taken regularly to be effective. Do not skip doses even if you feel that you do not need them. Do not take chlordiazepoxide for more than 4 months or stop taking this medication without talking to your doctor. Stopping the drug suddenly can worsen your condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability). Your doctor probably will decrease your dose gradually.
Side effects
<p></p> <p></p> <p></p> <p>Side effects from chlordiazepoxide are common and include:
<ul>
<li>
drowsiness</li>
<li>
dizziness</li>
<li>
tiredness</li>
<li>
weakness</li>
<li>
dry mouth</li>
<li>
diarrhea</li>
<li>
upset stomach</li>
<li>
changes in appetite</li></ul>Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
restlessness or excitement</li>
<li>
constipation</li>
<li>
difficulty urinating</li>
<li>
frequent urination</li>
<li>
blurred vision</li>
<li>
changes in sex drive or ability</li></ul></p> <p></p> <p>If you experience any of the following symptoms, call your doctor immediately:
<ul>
<li>
shuffling walk</li>
<li>
persistent, fine tremor or inability to sit still</li>
<li>
fever</li>
<li>
difficulty breathing or swallowing</li>
<li>
severe skin rash</li>
<li>
yellowing of the skin or eyes</li>
<li>
irregular heartbeat</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
<ul>
<li>
drowsiness</li>
<li>
dizziness</li>
<li>
tiredness</li>
<li>
weakness</li>
<li>
dry mouth</li>
<li>
diarrhea</li>
<li>
upset stomach</li>
<li>
changes in appetite</li></ul>Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
restlessness or excitement</li>
<li>
constipation</li>
<li>
difficulty urinating</li>
<li>
frequent urination</li>
<li>
blurred vision</li>
<li>
changes in sex drive or ability</li></ul></p> <p></p> <p>If you experience any of the following symptoms, call your doctor immediately:
<ul>
<li>
shuffling walk</li>
<li>
persistent, fine tremor or inability to sit still</li>
<li>
fever</li>
<li>
difficulty breathing or swallowing</li>
<li>
severe skin rash</li>
<li>
yellowing of the skin or eyes</li>
<li>
irregular heartbeat</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
Precautions
Before taking chlordiazepoxide, tell your doctor and pharmacist if you are allergic to chlordiazepoxide, alprazolam (Xanax), clonazepam (Klonopin), clorazepate (Tranxene), diazepam (Valium), estazolam (ProSom), flurazepam (Dalmane), lorazepam (Ativan), oxazepam (Serax), prazepam (Centrax), temazepam (Restoril), triazolam (Halcion), or any other drugs. tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially antihistamines; cimetidine (Tagamet); digoxin (Lanoxin); disulfiram (Antabuse); fluoxetine (Prozac); isoniazid (INH, Laniazid, Nydrazid); ketoconazole (Nizoral); levodopa (Larodopa, Sinemet); medications for depression, seizures, Parkinson's disease, pain, asthma, colds, or allergies; metoprolol (Lopressor, Toprol XL); muscle relaxants; oral contraceptives; probenecid (Benemid); propoxyphene (Darvon); propranolol (Inderal); rifampin (Rifadin); sedatives; sleeping pills; theophylline (Theo-Dur); tranquilizers; valproic acid (Depakene); and vitamins. These medications may add to the drowsiness caused by chlordiazepoxide. tell your doctor if you have or have ever had glaucoma; seizures; or lung, heart, or liver disease. talk to your doctor about the risks and benefits of taking chlordiazepoxide if you are 65 years of age or older. Older adults should not usually take chlordiazepoxide because it is not as safe or effective as other medication(s) that can be used to treat the same condition. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking chlordiazepoxide. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this drug.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Chlordiazepoxide.