Cimetidine
Why this is used
Cimetidine is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome. Over-the-counter cimetidine is used to prevent and treat symptoms of heartburn associated with acid indigestion and sour stomach. Cimetidine is in a class of medications called H<span class='sub'>2</span> blockers. It decreases the amount of acid made in the stomach.
How to take it
Cimetidine comes as a tablet and a liquid to take by mouth. It is usually taken once a day at bedtime or two to four times a day with meals and at bedtime. Over-the-counter cimetidine is usually taken once or twice a day with a glass of water. To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn. Follow the directions on your prescription or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cimetidine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Do not take over-the-counter cimetidine for longer than 2 weeks unless your doctor tells you to. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking cimetidine and call your doctor.
Side effects
<p></p> <p></p> <p></p> <p>Cimetidine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
headache</li>
<li>
diarrhea</li>
<li>
dizziness</li>
<li>
drowsiness</li>
<li>
breast enlargement</li></ul></p> <p></p> <p>Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
<ul>
<li>
confusion</li>
<li>
excitement</li>
<li>
depression</li>
<li>
nervousness</li>
<li>
seeing things or hearing voices that do not exist (hallucinating)</li></ul>Cimetidine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
<ul>
<li>
headache</li>
<li>
diarrhea</li>
<li>
dizziness</li>
<li>
drowsiness</li>
<li>
breast enlargement</li></ul></p> <p></p> <p>Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
<ul>
<li>
confusion</li>
<li>
excitement</li>
<li>
depression</li>
<li>
nervousness</li>
<li>
seeing things or hearing voices that do not exist (hallucinating)</li></ul>Cimetidine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
Precautions
Before taking cimetidine, tell your doctor and pharmacist if you are allergic to cimetidine or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); chlordiazepoxide (Librium); clopidogrel (Plavix), diazepam (Valium); lidocaine (Xylocaine); metronidazole (Flagyl); nifedipine (Adalat, Procardia); phenytoin (Dilantin); propranolol (Inderal); and theophylline (Theobid, Theo-Dur). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. if you are taking antacids (Maalox, Mylanta, Tums), digoxin (Lanoxin), ketoconazole (Nizoral), or iron salts, take them 2 hours before cimetidine. tell your doctor if you have or have ever had human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), or kidney or liver disease. talk to your doctor about the risks and benefits of taking cimetidine if you are 65 years of age or older. Older adults should not usually take cimetidine because it is not as safe as other medication(s) that can be used to treat the same condition.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Cimetidine.