Colestipol

Why this is used

Colestipol is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to prevent heart disease, angina (chest pain), strokes, and heart attacks. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How to take it

Colestipol comes as granules to take by mouth. It usually is taken two to four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take colestipol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Take all other medications at least 1 hour before or 4 hours after you take colestipol because colestipol can interfere with their absorption. Continue to take colestipol even if you feel well. Do not stop taking colestipol without talking to your doctor. Do not take the granules dry. Add them to at least 3 ounces (90 milliliters) of a liquid (e.g., fruit juice, water, milk, or soft drink) and stir until completely mixed. If you use a carbonated beverage, mix it slowly in a large glass to minimize foaming. After taking the dose, rinse the glass with a small amount of additional liquid and drink it to be sure that you receive the entire dose. For convenience and to improve taste, mix your entire next-day's dose in a liquid in the evening and refrigerate it. Colestipol also may be mixed with hot or regular breakfast cereals, thin soups (e.g., tomato and chicken noodle), or pulpy fruit (e.g., crushed pineapple, pears, peaches, and fruit cocktail).

Side effects

<p></p> <p></p> <p></p> <p>Colestipol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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constipation</li>
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belching</li>
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nausea</li>
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vomiting</li>
<li>
gas</li></ul></p> <p></p> <p>If you experience the following symptom, call your doctor immediately:

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unusual bleeding (such as bleeding from the gums or rectum)</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before taking colestipol, tell your doctor and pharmacist if you are allergic to colestipol or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially amiodarone (Cordarone), antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin), digitoxin, digoxin (Lanoxin), diuretics ('water pills'), iron, loperamide (Imodium), mycophenolate (Cellcept), oral diabetes medications, phenobarbital, phenylbutazone, propranolol (Inderal), thyroid medications, and vitamins. tell your doctor if you have or have ever had unusual bleeding, an underactive thyroid gland, heart or intestinal disease, or if you have hemorrhoids.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Colestipol.