Degarelix Injection

Why this is used

Degarelix injection is used to treat advanced prostate cancer (cancer that begins in the prostate [a male reproductive gland]). Degarelix injection is in a class of medications called gonadotropin-releasing (GnRH) receptor antagonists. It works by decreasing the amount of testosterone (a male hormone) produced by the body. This may slow or stop the spread of prostate cancer cells that need testosterone to grow.

How to take it

Degarelix injection comes as a solution (liquid) to be injected under the skin in the stomach area, away from the ribs and waistline. It is usually injected once every 28 days by a doctor or nurse in a medical facility. After you receive a dose of degarelix injection, be sure that your belt or waistband does not put pressure on the place where the medication was injected. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Side effects

<p></p> <p></p> <p></p> <p>Degarelix injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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pain, redness, swelling, hardness, or itching in the place where the medication was injected</li>
<li>
hot flashes</li>
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excessive sweating or night sweats</li>
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nausea</li>
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constipation</li>
<li>
diarrhea</li>
<li>
weight gain</li>
<li>
weakness</li>
<li>
dizziness</li>
<li>
headache</li>
<li>
tiredness</li>
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difficulty falling asleep or staying asleep</li>
<li>
enlargement of the breasts</li>
<li>
decreased sexual desire or ability</li>
<li>
back or joint pain</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

<ul>
<li>
fluttering feeling in the chest</li>
<li>
fainting</li>
<li>
painful, frequent, or difficult urination</li>
<li>
fever or chills</li></ul>Degarelix injection may cause your bones to become weaker and more brittle than they were at the beginning of your treatment. Talk to your doctor about the risks of taking this medication.Degarelix injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before receiving degarelix injection, tell your doctor and pharmacist if you are allergic to degarelix injection, any other medications, or any of the ingredients in degarelix injection. Ask your pharmacist or check the patient information for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone), disopyramide (Norpace), quinidine, procainamide, or sotalol. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had long QT syndrome (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death); high or low levels of calcium, potassium, magnesium, or sodium in your blood; or heart, liver, or kidney disease.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Degarelix Injection.