Delavirdine

Delavirdine is used to treat human immunodeficiency virus (HIV) infection in patients with or without acquired immunodeficiency syndrome (AIDS). Delavirdine is not a cure and may not decrease the number of HIV-related illnesses. Delavirdine does not prevent the spread of HIV to other people. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Delavirdine comes as a tablet to take by mouth. It usually is taken three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take delavirdine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you have trouble swallowing the tablets, they may be dispersed in water. To prepare, add four tablets to at least 3 ounces (88 milliliters) of water, allow to stand for a few minutes, and then stir until a uniform dispersion occurs. Drink the delavirdine-water mixture right away. Rinse the glass and swallow the rinse to ensure that you have gotten the entire dose. If you are taking antacids, wait at least 1 hour between taking the antacid and taking delavirdine.

<p></p> <p></p> <p></p> <p>Side effects from delavirdine are common. Tell your doctor if any of these symptoms are severe or do not go away:

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excessive tiredness</li>
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headache</li>
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upset stomach</li>
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diarrhea</li>
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vomiting</li>
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hallucinations</li>
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nightmares</li>
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decreased libido (sex drive)</li>
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rash</li></ul></p> <p></p> <p>If you experience any of the following symptoms, or those listed in the IMPORTANT WARNING section, call your doctor immediately:

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chest pain</li>
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irregular heartbeat</li>
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hives</li>
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itching</li>
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difficulty breathing or swallowing</li>
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wheezing</li>
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fainting</li>
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severe skin rash accompanied by fever, blistering, oral lesions, red eyes, swelling, or muscle or joint pain</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Before taking delavirdine, tell your doctor and pharmacist if you are allergic to delavirdine or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially amprenavir (Agenerase); antacids; anticonvulsants such as carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), and valproic acid (Depakene); anticoagulants ('blood thinners') such as warfarin (Coumadin); antihistamines such as astemizole (Hismanal) and terfenadine (Seldane); benzodiazepines such as alprazolam (Xanax), midazolam (Versed), and triazolam (Halcion); calcium channel blockers such as amlodipine (Norvasc), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), and nisoldipine (Sular); cisapride (Propulsid); clarithromycin (Biaxin); dapsone; ergot derivatives such as dihydroergotamine mesylate (DHE 45), ergotamine tartrate (Ergostat, Medihaler Ergotamine); fluoxetine (Prozac); medications for stomach acid such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac); quinidine (Quinaglute); rifabutin (Mycobutin); rifampin (Rifadin); sildenafil (Viagra); and vitamins. tell your doctor if you have or have ever had liver disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking delavirdine.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.