Dornase Alfa

Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Dornase alfa comes as a solution to inhale by mouth. It usually is taken one or two times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use dornase alfa exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Dornase alfa is used to treat cystic fibrosis but does not cure it. Continue to use dornase alfa even if you feel well. Do not stop using dornase alfa without talking to your doctor. Before you use dornase alfa the first time, read the written instructions that come with it. Ask your doctor, pharmacist, or respiratory therapist to demonstrate the proper technique. Practice using the nebulizer while in his or her presence. Only use a nebulizer that is recommended by your doctor.

<p></p> <p></p> <p></p> <p>Dornase alfa may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away.

<ul>
<li>
voice changes</li>
<li>
sore throat</li>
<li>
hoarseness</li>
<li>
eye irritation</li>
<li>
rash</li></ul></p> <p></p> <p>If you experience either of the following symptoms, call your doctor immediately.

<ul>
<li>
increased difficulty breathing</li>
<li>
chest pain</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Before using dornase alfa, tell your doctor and pharmacist if you are allergic to dornase alfa or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.