Doxepin Topical

Why this is used

Doxepin topical is used to relieve itching of the skin caused by eczema. Doxepin is in a class of medications called topical antipruritics. It may work by blocking histamine, a substance in the body that causes certain symptoms, such as itching.

How to take it

Doxepin comes as a cream to apply to the skin. It is usually applied four times a day, at least 3 to 4 hours apart, for up to 8 days. Use doxepin at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use doxepin topical exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. To use the cream, follow these steps:

<list list-type='ordered' numbering='arabic'>
<li>
Wash the affected skin with water and a mild soap or soapless cleansing lotion and pat dry with a soft towel.</li>
<li>
Apply a thin layer of cream to the affected skin. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If you do get doxepin in your eyes, wash with plenty of water and call your doctor if your eyes are irritated.</li>
<li>
Do not cover the affected area with any bandages, dressings, or wrappings.</li>
<li>
Wash your hands with soap and water after you finish handling the medication.</li></ul>

Side effects

<p></p> <p></p> <p></p> <p>Doxepin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

<ul>
<li>
drowsiness</li>
<li>
dry mouth</li>
<li>
dry lips</li>
<li>
thirst</li>
<li>
headache</li>
<li>
extreme tiredness</li>
<li>
dizziness</li>
<li>
mood changes</li>
<li>
taste changes</li>
<li>
burning or stinging at affected area</li>
<li>
worsened itching</li>
<li>
dryness and tightness of skin at affected area</li>
<li>
tingling of the fingers or toes</li>
<li>
swelling of the affected area</li></ul>Doxepin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.</p> <p></p> <p></p>

Precautions

Before using doxepin cream, tell your doctor and pharmacist if you are allergic to doxepin (Adapin, Sinequan) or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants (mood elevators); antihistamines; carbamazepine (Tegretol); cimetidine (Tagamet); medications for irregular heartbeat, including encainide (Enkaid), flecainide (Tambocor), propafenone (Rythmol), and quinidine (Quinaglute, Quinidex); and medications for mental illness and nausea. Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past 2 weeks: monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had glaucoma, benign prostatic hypertrophy (enlargement of the prostate), or urinary retention (inability to empty your bladder completely or at all). if you are having surgery, including dental surgery, tell the doctor or dentist that you are using doxepin. you should know that doxepin may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. If you become very drowsy from doxepin, talk to your doctor. remember that alcohol can add to the drowsiness caused by this medication.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:

<ul>
<li>
drowsiness</li>
<li>
unconsciousness</li>
<li>
blurred vision</li>
<li>
very dry mouth</li>
<li>
difficulty breathing</li>
<li>
dizziness</li>
<li>
fainting</li>
<li>
seizures</li>
<li>
change in body temperature</li>
<li>
fast or irregular heart beat</li>
<li>
urinary retention</li>
<li>
enlarged pupils (dark part of eye)</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Doxepin Topical.