Eribulin Injection
Why this is used
Eribulin injection is used to treat breast cancer that has spread to other parts of the body and that has already been treated with certain other chemotherapy medications. Eribulin is in a class of anticancer medications called microtubule dynamics inhibitors. It works by stopping the growth and spread of cancer cells.
How to take it
Eribulin injection comes as a solution (liquid) to be given intravenously (into a vein) over 2 to 5 minutes by a doctor or nurse in a medical office, infusion center, or hospital. It is usually given on days 1 and 8 of a 21-day cycle. Your doctor may need to delay your treatment or decrease your dose if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Side effects
<p></p> <p></p> <p></p> <p>Eribulin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
nausea</li>
<li>
constipation</li>
<li>
loss of appetite</li>
<li>
weight loss</li>
<li>
headache</li>
<li>
weakness</li>
<li>
tiredness</li>
<li>
bone, back, or joint pain</li>
<li>
hair loss</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
<ul>
<li>
sore throat, cough, fever (temperature greater than 100.5), chills, burning or pain when urinating, or other signs of infection</li>
<li>
numbness, burning, or tingling in the arms, legs, hands, or feet</li>
<li>
pale skin</li>
<li>
shortness of breath</li>
<li>
irregular heartbeat</li></ul>Eribulin injection may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
<ul>
<li>
nausea</li>
<li>
constipation</li>
<li>
loss of appetite</li>
<li>
weight loss</li>
<li>
headache</li>
<li>
weakness</li>
<li>
tiredness</li>
<li>
bone, back, or joint pain</li>
<li>
hair loss</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
<ul>
<li>
sore throat, cough, fever (temperature greater than 100.5), chills, burning or pain when urinating, or other signs of infection</li>
<li>
numbness, burning, or tingling in the arms, legs, hands, or feet</li>
<li>
pale skin</li>
<li>
shortness of breath</li>
<li>
irregular heartbeat</li></ul>Eribulin injection may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
Precautions
Before receiving eribulin injection, tell your doctor and pharmacist if you are allergic to eribulin, any other medications, or any of the ingredients in eribulin injection. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone), clarithromycin (Biaxin); disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq); erythromycin (E.E.S., E-Mycin, Erythrocin), ibutilide (Corvert); certain medications for mental illness such as chlorpromazine, haloperidol (Haldol), and thioridazine; methadone (Dolophine), moxifloxacin (Avelox), pimozide (Orap), procainamide, quinidine, and sotalol (Betapace, Betapace AF),. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had long QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause loss of consciousness or sudden death); a slow heartbeat; low levels of potassium or magnesium in your blood; or heart, liver, or kidney disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving eribulin injection.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include the following:
<ul>
<li>
sore throat, cough, fever, chills, burning or pain when urinating, or other signs of infection</li></ul>
<ul>
<li>
sore throat, cough, fever, chills, burning or pain when urinating, or other signs of infection</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Eribulin Injection.