Levofloxacin Injection

Levofloxacin injection is used to treat infections such as pneumonia; chronic bronchitis; and sinus, urinary tract, kidney, prostate (a male reproductive gland), and skin infections. Levofloxacin injection is also used to prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax germs in the air. Levofloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. Antibiotics will not work for colds, flu, or other viral infections.

Levofloxacin injection comes as a solution (liquid) to be given through a needle or catheter placed in your vein. It is usually infused (injected slowly) intravenously (into a vein) over a period of 60 or 90 minutes, once every 24 hours. The length of your treatment depends on the type of infection you have. Your doctor will tell you how long to use levofloxacin injection. You may receive levofloxacin injection in a hospital or you may use the medication at home. If you are using levofloxacin injection at home, use it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or other healthcare provider to explain any part you do not understand. Use levofloxacin injection exactly as directed. Do not infuse it more quickly than directed. Do not use more or less of it or use it more often than prescribed by your doctor. If you will be using levofloxacin injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing levofloxacin injection. You should begin feeling better during the first few days of your treatment with levofloxacin injection. If your symptoms do not improve, or if they get worse, call your doctor. Use levofloxacin injection until you finish the prescription, even if you feel better. Do not stop using levofloxacin injection unless you experience the symptoms of tendinitis or tendon rupture described in the IMPORTANT WARNING section or the symptoms of allergic reaction described in the SIDE EFFECTS section. If you stop using levofloxacin injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

<p></p> <p></p> <p></p> <p>Levofloxacin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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nausea</li>
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vomiting</li>
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stomach pain</li>
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constipation</li>
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heartburn</li>
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diarrhea</li>
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headache</li>
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vaginal itching and/or discharge</li>
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irritation, pain, tenderness, redness, warmth, or swelling at the injection spot</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, or those mentioned in the IMPORTANT WARNING section, stop using levofloxacin injection, and call your doctor immediately:

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severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)</li>
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rash or blisters</li>
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hives</li>
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itching</li>
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tingling or swelling of the face, neck, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs</li>
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difficulty breathing or swallowing</li>
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hoarseness or throat tightness</li>
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fainting</li>
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rapid, irregular, or pounding heartbeat</li>
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chest pain</li>
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joint or muscle pain</li>
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fever</li>
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unusual bruising or bleeding</li>
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extreme tiredness</li>
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lack of energy</li>
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loss of appetite</li>
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pain in the upper right part of the stomach</li>
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yellowing of the skin or eyes</li>
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dark urine</li>
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pale stools</li>
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flu-like symptoms</li>
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seizures</li>
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dizziness</li>
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confusion</li>
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nervousness</li>
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restlessness</li>
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anxiety</li>
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not trusting others or feeling that others want to hurt you</li>
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difficulty falling asleep or staying asleep</li>
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nightmares or abnormal dreams</li>
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hallucinations (seeing things or hearing voices that do not exist)</li>
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depression</li>
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thoughts about dying or killing yourself</li>
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uncontrollable shaking of a part of the body</li>
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pain, burning, tingling, numbness, and/or weakness in a part of the body</li></ul>Levofloxacin injection may cause problems with bones, joints, and tissues around joints in children. Levofloxacin injection should not normally be given to children younger than 18 years old unless they have been exposed to anthrax in the air. If your doctor prescribes levofloxacin injection for your child, be sure to tell the doctor if your child has or has ever had joint-related problems. Call your doctor if your child develops joint problems, such as pain or swelling, while using levofloxacin injection or after treatment with levofloxacin injection. Talk to your child's doctor about the risks of giving levofloxacin injection to your child.Levofloxacin injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Before using levofloxacin injection, tell your doctor and pharmacist if you are allergic or have had a severe reaction to levofloxacin; any other quinolone or fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the US), gemifloxacin (Factive), lomefloxacin (Maxaquin) (not available in the US), moxifloxacin (Avelox), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the US); or any other medications. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); insulin; oral medications for diabetes such as glyburide (DiaBeta, in Glucovance, Micronase, others); certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); tacrolimus (Prograf); or theophylline (Elixophyllin, Theo-24, Uniphyl, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you or anyone in your family has or has ever had prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death) or an irregular heartbeat and if you have or have ever had nerve problems; a low level of potassium in your blood; cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke); seizures; slow heartbeat; chest pain; or liver disease. you should know that levofloxacin injection may cause confusion, dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how this medication affects you. plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Levofloxacin injection may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, like a bad sunburn, call your doctor.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.