Liraglutide Injection

Why this is used

Liraglutide injection is used with a diet and exercise program to control blood sugar levels in adults with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) when other medications did not control levels well enough. Liraglutide injection is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated). Liraglutide injection is in a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood into other body tissues where it is used for energy. Liraglutide injection also slows the emptying of the stomach and may decrease appetite and cause weight loss.

How to take it

Liraglutide injection comes as a solution (liquid) in a prefilled dosing pen to inject subcutaneously (under the skin) in your stomach, thigh, or upper arm. It is usually injected once a day with or without food. Use liraglutide injection at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use liraglutide injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Your doctor will probably start you on a low dose of liraglutide injection and increase your dose after one week. Liraglutide injection controls diabetes but does not cure it. Continue to use liraglutide injection even if you feel well. Do not stop using liraglutide injection without talking to your doctor. You will need to buy needles separately. Ask your doctor or pharmacist what type of needles you will need to inject your medication. Be sure to read and understand the manufacturer's instructions for injecting liraglutide using the pen. Also make sure you know how and when to set up a new pen, and what to do if you drop your pen. Ask your doctor or pharmacist to show you how to use the pen. Follow the directions carefully. Always look at your liraglutide solution before you inject it. It should be clear, colorless, and free of particles. Do not use liraglutide if it is colored, cloudy, thickened, or contains solid particles, or if the expiration date on the bottle has passed. Never reuse needles and never share needles or pens. Always remove the needle right after you inject your dose. Throw away needles in a puncture-resistant container. Ask your doctor or pharmacist how to dispose of the puncture resistant container. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Side effects

<p>This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.</p> <p></p> <p></p> <p>Liraglutide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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headache</li>
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nausea</li>
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diarrhea</li>
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constipation</li>
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heartburn</li>
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loss of appetite</li>
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runny nose</li>
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sneezing</li>
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cough</li>
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tiredness</li>
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difficulty urinating or pain or burning on urination</li>
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rash or redness in the place where the medication was injected</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience either of these symptoms or those listed in the IMPORTANT WARNING section, stop using liraglutide injection and call your doctor immediately:

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ongoing pain that begins in the upper left or middle of the stomach but may spread to the back </li>
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vomiting</li></ul>Liraglutide injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before using liraglutide injection, tell your doctor and pharmacist if you are allergic to liraglutide, any other medications, or any of the ingredients in liraglutide injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. It is especially important to tell your doctor about all the medications you take by mouth because liraglutide may change the way your body absorbs these medications. Also be sure to mention insulin or oral medications for diabetes especially sulfonylureas, including chlorpropamide (Diabinese), glimepiride (Amaryl, in Avandaryl, in Duetact), glipizide (Glucotrol, in Metaglip), glyburide (DiaBeta, in Glucovance, Glycron, Glynase, Micronase), tolazamide, and tolbutamide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you drink or have ever drunk large amounts of alcohol and if you have or have ever had pancreatitis (inflammation of the pancreas); severe stomach problems, including gastroparesis (slowed movement of food from the stomach to the small intestine) or problems digesting food; a high level of triglycerides (fats) in the blood; gallstones (solid deposits that form in the gallbladder); or kidney or liver disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are using liraglutide injection. ask your doctor what to do if you get sick, develop an infection or fever, experience unusual stress, or are injured. These conditions can affect your blood sugar and the amount of liraglutide you may need.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:

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severe nausea</li>
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severe vomiting</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Liraglutide Injection.