Metoclopramide Injection

Metoclopramide injection is used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide injection is also used to prevent nausea and vomiting caused by chemotherapy or that may occur after surgery. Metoclopramide injection is also sometimes used to empty the intestines during certain medical procedures. Metoclopramide injection is in a class of medications called prokinetic agents. It works by speeding the movement of food through the stomach and intestines.

Metoclopramide injection comes as a liquid to be injected into a muscle or into a vein. When metoclopramide injection is used to treat slowed stomach emptying due to diabetes, it may be given up to four times a day. When metoclopramide injection is used to prevent nausea and vomiting due to chemotherapy, it is usually given 30 minutes before the chemotherapy, then once every 2 hours for two doses, then once every 3 hours for three doses. Metoclopramide injection is also sometimes given during surgery. If you are injecting metoclopramide injection at home, inject it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use metoclopramide injection exactly as directed. Do not inject more or less of it or inject it more often than prescribed by your doctor.

<p></p> <p></p> <p></p> <p>Metoclopramide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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drowsiness</li>
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excessive tiredness</li>
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weakness</li>
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headache</li>
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dizziness</li>
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restlessness</li>
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nervousness or jitteriness</li>
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agitation</li>
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difficulty falling asleep or staying asleep</li>
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pacing</li>
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foot tapping</li>
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slow or stiff movements</li>
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blank facial expression</li>
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diarrhea</li>
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nausea</li>
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breast enlargement or discharge</li>
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missed menstrual period</li>
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decreased sexual ability</li>
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frequent urination</li>
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urinary incontinence</li>
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flushing</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

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tightening of the muscles, especially in the jaw or neck</li>
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speech problems</li>
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depression</li>
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thinking about harming or killing yourself</li>
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fever</li>
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muscle stiffness</li>
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confusion</li>
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fast, slow, or irregular heartbeat</li>
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sweating</li>
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seizures</li>
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rash</li>
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hives</li>
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swelling of the eyes, face, lips, tongue, mouth, throat, arms, hands, feet, ankles, or lower legs</li>
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difficulty breathing or swallowing</li>
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high-pitched sounds while breathing</li>
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vision problems</li></ul>Metoclopramide injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Before receiving metoclopramide injection, tell your doctor and pharmacist if you are allergic to metoclopramide injection, any other medications, or any of the ingredients in metoclopramide injection. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol, others); antihistamines; digoxin (Lanoxicaps, Lanoxin); cyclosporine (Gengraf, Neoral, Sandimmune); insulin; ipratropium (Atrovent); levodopa (in Sinemet, in Stalevo); medications for irritable bowel disease, motion sickness, Parkinson's disease, ulcers, or urinary problems; monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); narcotic medications for pain; sedatives; sleeping pills; tetracycline (Bristacycline, Sumycin); tranquilizers. Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. tell your doctor if you have or have ever had blockage or bleeding in your stomach or intestines, pheochromocytoma (tumor on a small gland near the kidneys); or seizures. Your doctor will probably tell you not to take metoclopramide. tell your doctor if you have or have ever had Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance); high blood pressure; depression; breast cancer; asthma;glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disorder); NADH cytochrome B5 reductase deficiency (an inherited blood disorder); or heart, liver, or kidney disease. you should know that metoclopramide injection may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. ask your doctor about the safe use of alcoholic beverages while you are receiving metoclopramide injection. Alcohol can make the side effects from metoclopramide injection worse.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include

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drowsiness</li>
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confusion</li>
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unusual, uncontrollable movements</li></ul>