Metolazone

Metolazone, a 'water pill,' is used to treat high blood pressure and fluid retention caused by various conditions, including heart disease. It causes the kidneys to get rid of unneeded water and salt from the body into the urine. This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Metolazone comes as a tablet to take by mouth. It usually is taken once a day in the morning. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metolazone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Metolazone controls high blood pressure but does not cure it. Continue to take metolazone even if you feel well. Do not stop taking metolazone without talking to your doctor.

<p></p> <p></p> <p></p> <p>Frequent urination should go away after you take metolazone for a few weeks. Tell your doctor if any of these symptoms are severe or do not go away:

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muscle weakness</li>
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dizziness</li>
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cramps</li>
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thirst</li>
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stomach pain</li>
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upset stomach</li>
<li>
vomiting</li>
<li>
diarrhea</li>
<li>
headache</li>
<li>
hair loss</li></ul></p> <p></p> <p>If you experience any of the following symptoms, call your doctor immediately:

<ul>
<li>
sore throat with fever</li>
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unusual bleeding or bruising</li>
<li>
severe skin rash with peeling skin</li>
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difficulty breathing or swallowing</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Before taking metolazone, tell your doctor and pharmacist if you are allergic to metolazone, sulfa drugs, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other medications for high blood pressure, anti-inflammatory medications such as ibuprofen (Motrin, Nuprin) or naproxen (Aleve), corticosteroids (e.g., prednisone), lithium (Eskalith, Lithobid), medications for diabetes, probenecid (Benemid), and vitamins. If you also are taking cholestyramine or colestipol, take it at least 1 hour after metolazone. tell your doctor if you have or have ever had diabetes, gout, or kidney, liver, thyroid, or parathyroid disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking metolazone. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Metolazone may make your skin sensitive to sunlight.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.