Nateglinide Oral
Why this is used
Nateglinide is used alone or in combination with other medications to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) in people whose diabetes cannot be controlled by diet and exercise alone. Nateglinide belongs to a class of drugs called meglitinides. Nateglinide helps your body regulate the amount of glucose (sugar) in your blood. It decreases the amount of glucose by stimulating the pancreas to release insulin.
How to take it
Nateglinide comes as a tablet to take by mouth. It is usually taken three times daily. Take nateglinide any time from 30 minutes before a meal to just before the meal. If you skip a meal, you need to skip the dose of nateglinide. If you add a meal, add a dose of nateglinide. Your doctor may gradually increase your dose, depending on your response to nateglinide. Monitor your blood glucose closely. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nateglinide exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor. Nateglinide controls diabetes but does not cure it. Continue to take nateglinide even if you feel well. Do not stop taking nateglinide without talking with your doctor.
Side effects
<p>This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.</p> <p>You may experience hypoglycemia (low blood sugar) while you are taking this medication. Your doctor will tell you what you should do if you develop hypoglycemia. He or she may tell you to check your blood sugar, eat or drink a food or beverage that contains sugar, such as hard candy or fruit juice, or get medical care. Follow these directions carefully if you have any of the following symptoms of hypoglycemia:
<ul>
<li>
shakiness</li>
<li>
dizziness or lightheadedness</li>
<li>
sweating</li>
<li>
nervousness or irritability</li>
<li>
sudden changes in behavior or mood</li>
<li>
headache</li>
<li>
numbness or tingling around the mouth</li>
<li>
weakness</li>
<li>
pale skin </li>
<li>
hunger</li>
<li>
clumsy or jerky movements</li></ul>If hypoglycemia is not treated, severe symptoms may develop. Be sure that your family, friends, and other people who spend time with you know that if you have any of the following symptoms, they should get medical treatment for you immediately.
<ul>
<li>
confusion</li>
<li>
seizures</li>
<li>
loss of consciousness</li></ul></p> <p></p> <p>Nateglinide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
headache</li>
<li>
nasal congestion</li>
<li>
runny nose</li>
<li>
joint aches</li>
<li>
back pain</li>
<li>
constipation</li>
<li>
cough</li>
<li>
flu-like symptoms</li></ul></p> <p></p>
<ul>
<li>
shakiness</li>
<li>
dizziness or lightheadedness</li>
<li>
sweating</li>
<li>
nervousness or irritability</li>
<li>
sudden changes in behavior or mood</li>
<li>
headache</li>
<li>
numbness or tingling around the mouth</li>
<li>
weakness</li>
<li>
pale skin </li>
<li>
hunger</li>
<li>
clumsy or jerky movements</li></ul>If hypoglycemia is not treated, severe symptoms may develop. Be sure that your family, friends, and other people who spend time with you know that if you have any of the following symptoms, they should get medical treatment for you immediately.
<ul>
<li>
confusion</li>
<li>
seizures</li>
<li>
loss of consciousness</li></ul></p> <p></p> <p>Nateglinide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
<ul>
<li>
headache</li>
<li>
nasal congestion</li>
<li>
runny nose</li>
<li>
joint aches</li>
<li>
back pain</li>
<li>
constipation</li>
<li>
cough</li>
<li>
flu-like symptoms</li></ul></p> <p></p>
Precautions
Before taking nateglinide, tell your doctor and pharmacist if you are allergic to nateglinide or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially albuterol (Proventil, Ventolin); allergy or cold medications; aspirin and nonsteroidal anti-inflammatory drugs such as ibuprofen (Advil, Motrin) or naproxen (Aleve, Naprosyn); beta-blockers such as propranolol (Inderal); chloramphenicol (Chloromycetin); chlorpromazine (Thorazine); corticosteroids such as dexamethasone (Decadron), methylprednisolone (Medrol), or prednisone (Deltasone, Orasone); diuretics ('water pills'); epinephrine; estrogens; fluphenazine (Prolixin); isoniazid (Rifamate); medications that contain alcohol or sugar; mesoridazine (Serentil); niacin; oral contraceptives (birth control pills); perphenazine (Trilafon); phenelzine (Nardil); probenecid (Benemid); prochlorperazine (Compazine); promazine (Sparine); promethazine (Phenergan); terbutaline (Brethine, Bricanyl); thioridazine (Mellaril); thyroid medication; tranylcypromine (Parnate); trifluoperazine (Stelazine); triflupromazine (Vesprin); trimeprazine (Temaril); and vitamins or herbal products. tell your doctor if you have or have ever had liver or pituitary disease, adrenal insufficiency, diabetic ketoacidosis, neuropathy (disease of the nervous system), or if you have been told you have type 1 diabetes mellitus (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) . if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nateglinide. tell your doctor if you have fever, infection, injury, or illness with vomiting or diarrhea. These may affect your blood sugar level.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Nateglinide Oral.