Nepafenac Ophthalmic

Why this is used

Ophthalmic nepafenac is used to treat eye pain, redness, and swelling in patients who are recovering from cataract surgery (procedure to treat clouding of the lens in the eye). Nepafenac is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the production of certain natural substances that cause pain and swelling.

How to take it

Ophthalmic nepafenac comes as a suspension (liquid) to instill in the eyes. It is usually instilled three times a day beginning one day before cataract surgery, on the day of the surgery, and for 14 days after the surgery. Use nepafenac eye drops at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nepafenac eye drops exactly as directed. Do not use more or less of them or use them more often than prescribed by your doctor. To use the eye drops, follow these steps:

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Wash your hands thoroughly with soap and water.</li>
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Check the dropper tip to make sure that it is not chipped or cracked.</li>
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Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.</li>
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While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.</li>
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Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.</li>
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Brace the remaining fingers of that hand against your face.</li>
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While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.</li>
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Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.</li>
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Place a finger on the tear duct and apply gentle pressure.</li>
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Wipe any excess liquid from your face with a tissue.</li>
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If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.</li>
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Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.</li>
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Wash your hands to remove any medication.</li></ul>

Side effects

<p></p> <p></p> <p></p> <p>Nepafenac eye drops may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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headache</li>
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runny nose</li>
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pain or pressure in the face</li>
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nausea</li>
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vomiting</li>
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dry, itchy, or sticky eyes</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

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red or bloody eyes</li>
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eye pain</li>
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feeling that something is in the eye</li>
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sensitivity to light</li>
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blurred or decreased vision</li>
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seeing specks or spots</li>
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teary eyes</li>
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eye discharge or crusting</li></ul>Nepafenac eye drops may cause other side effects. Call your doctor if you have any unusual problems while using this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before using nepafenac eye drops, tell your doctor and pharmacist if you are allergic to nepafenac; aspirin or other NSAIDs such as diclofenac (Voltaren), ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), or tolmetin (Tolectin); any other medications, or any of the ingredients in nepafenac eye drops. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); aspirin and other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); and corticosteroid eye drops such as dexamethasone (Maxidex), fluorometholone (FML), hydrocortisone (in Cortisporin), loteprednol (Alrex, Lotemax), medrysone (HMS), prednisolone (Pred Mild), and rimexolone (Vexol). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. if you are using another topical eye medication, instill it at least 5 minutes before or after you instill nepafenac eye drops. tell your doctor if you have or have ever had diabetes, rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), dry eye disease or any eye problem other than cataracts, or any condition that causes you to bleed easily. if you wear contact lenses, remove them before you use nepafenac eye drops.
Educational reference only — talk to a pharmacist or prescriber about Nepafenac Ophthalmic.