Nitazoxanide

Why this is used

Nitazoxanide is used to treat diarrhea in children and adults caused by the protozoa <span class='ital'>Cryptosporidium</span> or <span class='ital'>Giardia</span>. Protozoa are suspected as the cause when diarrhea lasts more than 7 days. Nitazoxanide is in a class of medications called antiprotozoal agents. It works by stopping the growth of certain protozoa that cause diarrhea.

How to take it

Nitazoxanide comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken with food every 12 hours for 3 days. Take nitazoxanide at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nitazoxanide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the suspension well before each use to mix the medication evenly.

Side effects

<p></p> <p></p> <p></p> <p>Nitazoxanide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

<ul>
<li>
stomach pain</li>
<li>
headache</li>
<li>
upset stomach</li>
<li>
vomiting</li>
<li>
discolored urine</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

<ul>
<li>
skin rash</li>
<li>
itching</li></ul>Nitazoxanide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before taking nitazoxanide, tell your doctor and pharmacist if you are allergic to nitazoxanide or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had human immunodeficiency virus (HIV), problems with the immune system, or liver or kidney disease.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Nitazoxanide.