Prazosin

Why this is used

Prazosin is used alone or in combination with other medications to treat high blood pressure. Prazosin is in a class of medications called alpha-blockers. It works by relaxing the blood vessels so that blood can flow more easily through the body.

How to take it

Prazosin comes as a capsule to take by mouth. It usually is taken two or three times a day at evenly spaced intervals. The first time taking prazosin, you should take it before you go to bed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take prazosin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on a low dose of prazosin and gradually increase your dose. Prazosin controls high blood pressure but does not cure it. Continue to take prazosin even if you feel well. Do not stop taking prazosin without talking to your doctor.

Side effects

<p></p> <p></p> <p></p> <p>Prazosin may cause side effects. Tell your doctor if any of these symptoms or those listed in the SPECIAL PRECAUTIONS section are severe or do not go away:

<ul>
<li>
weakness</li>
<li>
tiredness</li>
<li>
headache</li>
<li>
nausea</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

<ul>
<li>
hives</li>
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rash</li>
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itching</li>
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difficulty breathing</li>
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fast, pounding, or irregular heartbeat</li>
<li>
chest pain</li>
<li>
painful erection of the penis that lasts for hours</li></ul></p>

Precautions

Before taking prazosin, tell your doctor and pharmacist if you are allergic to prazosin, alfuzosin (Uroxatral), doxazosin (Cardura), terazosin (Hytrin), or any other medications. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention: beta-blockers such as propranolol (Inderal); medications for erectile dysfunction (ED) such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);and other medications for high blood pressure. tell your doctor if you have narcolepsy (a sleep disorder that may cause extreme sleepiness, sudden uncontrollable urge to sleep during daily activities) or if you have or have ever had prostate cancer or liver disease. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking prazosin. If you need to have eye surgery at any time during or after your treatment, be sure to tell your doctor that you are taking or have taken prazosin. you should know that this drug may make you drowsy or dizzy. Do not drive a car, operate machinery, or perform dangerous tasks for 24 hours after the first time you take prazosin or after your dose is increased. ask your doctor about the safe use of alcoholic beverages while you are taking prazosin. Alcohol can make the side effects from prazosin worse. you should know that prazosin may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking prazosin, when your dose is increased, or when another blood pressure medication is added to your treatment. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. If you experience these symptoms, sit or lie down. These symptoms may also occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot. If these symptoms do not improve, call your doctor.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:

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drowsiness</li>
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decreased reflexes</li>
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dizziness</li>
<li>
lightheadedness</li>
<li>
fainting</li></ul>
Educational reference only — talk to a pharmacist or prescriber about Prazosin.