Reserpine

Why this is used

Reserpine is used to treat high blood pressure. It also is used to treat severe agitation in patients with mental disorders. Reserpine is in a class of medications called rauwolfia alkaloids. It works by slowing the activity of the nervous system, causing the heartbeat to slow and the blood vessels to relax.

How to take it

Reserpine comes as a tablet to take by mouth. It usually is taken once daily. Take reserpine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take reserpine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Reserpine controls high blood pressure or symptoms of agitation, but does not cure them. Continue to take reserpine even if you feel well. Do not stop taking reserpine without talking to your doctor. If you suddenly stop taking reserpine you may develop high blood pressure and experience unwanted side effects.

Side effects

<p></p> <p></p> <p></p> <p>Reserpine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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dizziness</li>
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loss of appetite</li>
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diarrhea</li>
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upset stomach</li>
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vomiting</li>
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stuffy nose</li>
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headache</li>
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dry mouth</li>
<li>
decreased sexual ability</li></ul></p> <p></p> <p>Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

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depression</li>
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nightmares</li>
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fainting</li>
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slow heartbeat</li>
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chest pain</li>
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swollen ankles or feet</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].Reserpine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.</p>

Precautions

Before taking reserpine, tell your doctor and pharmacist if you are allergic to reserpine, aspirin, any other medications, tartrazine (a yellow dye in some processed foods and medications), or any of the ingredients in reserpine tablets. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take.Be sure to mention any of the following: amitriptyline (Elavil); clomipramine (Anafranil) desipramine (Norpramin), digoxin (Lanoxin), doxepin (Adepin, Sinequan), ephedrine, epinephrine, imipramine (Tofranil), monoamine oxidase (MAO inhibitors such as isoxcarboxazid (Marplan), phenelzine (Nardil) selegiline (Eldepryl, Emsam, Zelapar); and tranylcypromine (Parnate), methylphenidate (Ritalin), nortriptyline (Aventyl, Pamelor), phenylephrine, protriptyline (Vivactil), quinidine (Quinaglute),and trimipramine (Surmontil).Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had kidney disease, gallstones, ulcers, ulcerative colitis, a history of depression, or electric shock therapy. talk to your doctor about the risks and benefits of taking reserpine if you are 65 years of age or older. Older adults should not usually take high doses of reserpine because it is not as safe as other medications that can be used to treat the same condition. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking reserpine. you should know that this medication may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how it affects you. ask your doctor about the safe use of alcohol while you are taking reserpine. Alcohol can make the side effects from reserpine worse.

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Reserpine.