Terbinafine

Why this is used

Terbinafine is used to treat fungal infections of the toenail and fingernail. Terbinafine is in a class of medications called antifungals. It works by stopping the growth of fungi.

How to take it

Terbinafine comes as a tablet to take by mouth. It is usually taken once a day for 6 weeks for fingernail fungus and once a day for 12 weeks for toenail fungus. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take terbinafine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your fungus may not be completely cured until a few months after you finish taking terbinafine. This is because it takes time for a healthy nail to grow in.

Side effects

<p></p> <p></p> <p></p> <p>Terbinafine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

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diarrhea</li>
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upset stomach</li>
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stomach pain</li>
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rash</li>
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itching</li>
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hives</li>
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changes in taste or loss of taste</li></ul></p> <p></p> <p>Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

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<li>
upset stomach that does not go away</li>
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loss of appetite</li>
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extreme tiredness</li>
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vomiting</li>
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pain in the right upper part of the stomach</li>
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dark urine</li>
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pale stools</li>
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severe skin rash that keeps getting worse</li>
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fever, sore throat, and other signs of infection</li></ul>Terbinafine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>

Precautions

Before taking terbinafine, tell your doctor and pharmacist if you are allergic to terbinafine or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); beta-blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); cimetidine (Tagamet); medications that suppress the immune system such as azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex), sirolimus (Rapamune), and tacrolimus (Prograf); rifampin (Rifadin, Rimactane); and selegiline (Eldepryl). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had kidney or liver disease, human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS).

Overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Terbinafine.