Theophylline
Why this is used
Theophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How to take it
Theophylline comes as a tablet, capsule, solution, and syrup to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take theophylline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Take this medication with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not chew or crush the extended-release (long-acting) tablets; swallow them whole. Extended-release capsules (e.g., Theo-Dur Sprinkles) may be swallowed whole or opened and the contents mixed with soft food and swallowed without chewing. Theophylline controls symptoms of asthma and other lung diseases but does not cure them. Continue to take theophylline even if you feel well. Do not stop taking theophylline without talking to your doctor.
Side effects
<p></p> <p></p> <p></p> <p>Theophylline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away.
<ul>
<li>
upset stomach</li>
<li>
stomach pain</li>
<li>
diarrhea</li>
<li>
headache</li>
<li>
restlessness</li>
<li>
insomnia</li>
<li>
irritability</li></ul></p> <p></p> <p>If you experience any of the following symptoms, call your doctor immediately:
<ul>
<li>
vomiting</li>
<li>
increased or rapid heart rate</li>
<li>
irregular heartbeat</li>
<li>
seizures</li>
<li>
skin rash</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
<ul>
<li>
upset stomach</li>
<li>
stomach pain</li>
<li>
diarrhea</li>
<li>
headache</li>
<li>
restlessness</li>
<li>
insomnia</li>
<li>
irritability</li></ul></p> <p></p> <p>If you experience any of the following symptoms, call your doctor immediately:
<ul>
<li>
vomiting</li>
<li>
increased or rapid heart rate</li>
<li>
irregular heartbeat</li>
<li>
seizures</li>
<li>
skin rash</li></ul>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at <a href='http://www.fda.gov/Safety/MedWatch'>http://www.fda.gov/Safety/MedWatch</a>] or by phone [1-800-332-1088].</p>
Precautions
Before taking theophylline, tell your doctor and pharmacist if you are allergic to theophylline or any other drugs. tell your doctor and pharmacist what prescription medications you are taking, especially allopurinol (Zyloprim), azithromycin (Zithromax), carbamazepine (Tegretol), cimetidine (Tagamet), ciprofloxacin (Cipro), clarithromycin (Biaxin), diuretics ('water pills'), erythromycin, lithium (Eskalith, Lithobid), oral contraceptives, phenytoin (Dilantin), prednisone (Deltasone), propranolol (Inderal), rifampin (Rifadin), tetracycline (Sumycin), and other medications for infections or heart disease. tell your doctor and pharmacist what nonprescription medications and vitamins you are taking, including ephedrine, epinephrine, phenylephrine, phenylpropanolamine, or pseudoephedrine. Many nonprescription products contain these drugs (e.g., diet pills and medications for colds and asthma), so check labels carefully. Do not take these medications without talking to your doctor; they can increase the side effects of theophylline. tell your doctor if you have or have ever had seizures, ulcers, heart disease, an overactive or underactive thyroid gland, high blood pressure, or liver disease or if you have a history of alcohol abuse. tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of theophylline.
Overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Educational reference only — talk to a pharmacist or prescriber about Theophylline.