Relationship Graph Explorer

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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Allicin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Allicin

Helicobacter pylori (H. pylori) is classified as class I car 1 Atherosclerosis 1

📋 Sample Trials

NCT04545879

Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique

Completed

📊 Sample Meta-Analyses

CRD42019118199

Allicin for helicobacter pylori eradication: a meta-analysis of randomized controlled trials

Helicobacter pylori (H. pylori) is classified as class I carcinogens by the worl

📚 Sample References

PMID 32808945

Allicin inhibits osteoblast apoptosis and steroid-induced necrosis of femoral head progression by activating the PI3K/AKT pathway

Food Funct · 2020

PMID 33203103

Effects of Allicin on Pathophysiological Mechanisms during the Progression of Nephropathy Associated to Diabetes

Antioxidants (Basel) · 2020

PMID 34777295

The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells

Front Microbiol · 2021

⚗️ All Ingredient data fields for Allicin

⚗️ Identity

Name

Allicin

Aliases / Synonyms

539-86-6; Diallyl thiosulfinate; S-allyl prop-2-ene-1-sulfinothioate; Diallyldisulfid-S-oxid; Thio-2-propene-1-sulfinic acid S-allyl ester; Allylthiosulphinic acid allyl ester; 2-Propene-1-sulfinothioic acid, S-2-propenyl ester; DADSO; S-Allyl acrylo-1-sulphinothioate

🧪 Chemistry

Molecular Weight

162.2790

LogP

1.7553

Drug-likeness

0.452

Oral Bioavailability

78.4130

H-Bond Acceptors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C=CCSS(=O)CC=C

Isomeric SMILES

C=CCSS(=O)CC=C

InChIKey

JDLKFOPOAOFWQN-UHFFFAOYSA-N

InChI

InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2

🔗 External References

HERB DB

HBIN015200 ↗

PubChem CID

65036 ↗

CAS Number

539-86-6 ↗

NPASS

NPC2088

HIT

C0872

SymMap

280

TCMID

920; 34844

TCMSP

MOL008354

TCM-ID

7011

🔍 Raw view — every non-empty column on this row (34 fields)

name

Allicin

common names

herb ingredient id

HBIN015200

canonical smiles

C=CCSS(=O)CC=C

isomeric smiles

C=CCSS(=O)CC=C

inchi

InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2

inchikey

JDLKFOPOAOFWQN-UHFFFAOYSA-N

mol wt

162.2790

num h acceptors

num h donors

mol logp

1.7553

num rotatable bonds

drug likeness

0.452

ob score

78.4130

cas id

539-86-6

symmap mol id

280

tcmid ingredient id

920; 34844

tcmsp ingredient id

MOL008354

tcm id ingredient id

7011

pubchem cid

65036

npass id

NPC2088

hit id

C0872

🏥 Linked Health Topics

1 · diseases via target pathways

Atherosclerosis

syndrome

📋 Clinical Trials

1 · subject of clinical study

NCT04545879 Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascula

→ Atherosclerosis

📊 Meta-Analyses

1 · systematic review

CRD42019118199 Allicin for helicobacter pylori eradication: a meta-analysis of randomized contr

→ Helicobacter pylori (H. pylori) is classified as c

📚 PubMed References

7 · cited research

PMID 32808945 Allicin inhibits osteoblast apoptosis and steroid-induced necrosis of femoral he

Food Funct

PMID 33203103 Effects of Allicin on Pathophysiological Mechanisms during the Progression of Ne

Antioxidants (Basel)

PMID 34777295 The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells

Front Microbiol

PMID 35046802 Protective Effects of Allicin on Acute Myocardial Infarction in Rats via Hydroge

Front Pharmacol

PMID 35784719 Allicin Facilitates Airway Surface Liquid Hydration by Activation of CFTR

Front Pharmacol

PMID 36355777 Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via distu

Br J Pharmacol

PMID 36430776 Allicin and Capsaicin Ameliorated Hypercholesterolemia by Upregulating LDLR and

Int J Mol Sci

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables