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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Apocynin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Apocynin

Bronchial Asthma 1

📋 Sample Trials

NCT00992667

Inhaled Apocynin Decreases Reactive Oxygen Species Concentrations in Exhaled Breath Condensate in Mild Asthmatics

Completed · Phase 1

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

PMID 32251677

Apocynin prevents GM-CSF-induced-ERK1/2 activation and -neutrophil survival independently of its inhibitory effect on the phagocyte NADPH oxidase NOX2

Biochem Pharmacol · 2020

PMID 33668280

Effects of Apocynin on Heart Muscle Oxidative Stress of Rats with Experimental Diabetes: Implications for Mitochondria

Antioxidants (Basel) · 2021

PMID 33817783

Apocynin prevents cigarette smoking-induced loss of skeletal muscle mass and function in mice by preserving proteostatic signalling

Br J Pharmacol · 2021

⚗️ All Ingredient data fields for Apocynin

⚗️ Identity

Name

Apocynin

Aliases / Synonyms

Acetovanillone; 498-02-2; 4'-Hydroxy-3'-methoxyacetophenone; 1-(4-Hydroxy-3-methoxyphenyl)ethanone; Acetoguaiacone; Apocynine; Acetoguaiacon; 4-Acetyl-2-methoxyphenol; Acetovanilone

🧪 Chemistry

Molecular Weight

166.1760

LogP

1.6034

Drug-likeness

0.679

Oral Bioavailability

31.7120

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC(=O)C1=CC(=C(C=C1)O)OC

Isomeric SMILES

CC(=O)C1=CC(=C(C=C1)O)OC

InChIKey

DFYRUELUNQRZTB-UHFFFAOYSA-N

InChI

InChI=1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3

🔗 External References

HERB DB

PubChem CID

CAS Number

DrugBank

NPASS

NPC32163

HIT

C0916

TCMID

30622; 117

TCMSP

MOL002786

TCM-ID

10084; 7227

🔍 Raw view — every non-empty column on this row (34 fields)

name

Apocynin

common names

Acetovanillone; 498-02-2; 4'-Hydroxy-3'-methoxyacetophenone; 1-(4-Hydroxy-3-methoxyphenyl)ethanone; Acetoguaiacone; Apocynine; Acetoguaiacon; 4-Acetyl-2-methoxyphenol; Acetovanilone

herb ingredient id

HBIN016505

canonical smiles

CC(=O)C1=CC(=C(C=C1)O)OC

isomeric smiles

CC(=O)C1=CC(=C(C=C1)O)OC

inchi

InChI=1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3

inchikey

DFYRUELUNQRZTB-UHFFFAOYSA-N

mol wt

166.1760

num h acceptors

num h donors

mol logp

1.6034

num rotatable bonds

drug likeness

0.679

ob score

31.7120

cas id

498-02-2

tcmid ingredient id

30622; 117

tcmsp ingredient id

MOL002786

tcm id ingredient id

10084; 7227

pubchem cid

2214

drugbank id

DB12618

npass id

NPC32163

hit id

C0916

📋 Clinical Trials

1 · subject of clinical study

NCT00992667 Inhaled Apocynin Decreases Reactive Oxygen Species Concentrations in Exhaled Bre

→ Bronchial Asthma

📚 PubMed References

4 · cited research

PMID 32251677 Apocynin prevents GM-CSF-induced-ERK1/2 activation and -neutrophil survival inde

Biochem Pharmacol

PMID 33668280 Effects of Apocynin on Heart Muscle Oxidative Stress of Rats with Experimental D

Antioxidants (Basel)

PMID 33817783 Apocynin prevents cigarette smoking-induced loss of skeletal muscle mass and fun

Br J Pharmacol

PMID 34450167 Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated

Life Sci

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables