AlternativeMed
natural remedies · Ingredient

1,8 cineole

Formula: C10H18O · MW: 154.253 · Drug-likeness: 0.521

⚗️ Identity
Name
1,8 cineole
Aliases / Synonyms
Eucalyptol; cineole; 1,8-Cineole; 470-82-6; 1,8-Cineol; Cajeputol; 1,8-Epoxy-p-menthane; Eucalyptole; Eucapur; Zineol
🧪 Chemistry
Molecular Weight
154.2530
LogP
2.7441
Drug-likeness
0.521
H-Bond Acceptors
1
🔗 External References
PubChem CID
CAS Number
DrugBank
InChIKey
WEEGYLXZBRQIMU-UHFFFAOYSA-N
1
Clinical Trials
1
Meta-Analyses
5
PubMed References
Top Conditions Studied with 1,8 cineole
📋 Sample Trials
NCT05002192
A Retrospective, Real-world Study of ELP Used in the Expectorant Treatment of Community-acquired Pneumonia
Unknown · Community-acquired Pneumonia
📊 Sample Meta-Analyses
CRD42022294114
The Protective Effect of 1, 8-cineole (Eucalyptol) on Respiratory System:A Systematic Review and Meta-Analysis from animal studies
📚 Sample References
PMID 31883118
Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis
Br J Pharmacol · 2019
PMID 28240768
Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti-inflammatory effects of eucalyptol
Br J Pharmacol · 2017
PMID 31926243
1,8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs
Life Sci · 2020
PMID 34685597
1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis
Cells · 2021
PMID 35964659
Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization
Eur J Pharmacol · 2022