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Spices

Flavor, Aroma, Cooking Use & Health Facts.

Start in the kitchen: what each spice tastes and smells like, how it is used in cooking and how much is normal in food. Then see what research says about health, and where concentrated supplements are different from the spice on your shelf.

Spices library

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Start with taste and smell, the way you would in the kitchen. Pick a flavor to see the spices that have it.

Filter by your health goals (after the kitchen facts) Tap one or more health icons. The list below shows only what matches.

Explore all 80 spices

Ginger

Warming and pungent roots and seeds

Zingiber officinale

Rhizome

Hot / pungentWarm / woodySweet

Aroma: Fresh, citrusy and spicy when raw; warmer and sweeter when dried.

In the kitchen: curries, baking, tea and drinks, soups and stews, vegetables

Ginger is hot, sweet-spicy and fresh-smelling and used in curries, baking and drinks; research on nausea is promising in pregnancy but mixed elsewhere, and supplements have blood-thinner cautions.

  • Nausea in pregnancy
  • Motion-sickness nausea
  • Nausea after surgery
  • Menstrual cramps

More about Ginger

Galangal

Warming and pungent roots and seeds

Alpinia galanga

Rhizome

Hot / pungentCitrusy

Aroma: Pungent and piney, with notes of citrus and black pepper.

In the kitchen: curries, soups and stews

Galangal is piney, peppery and citrusy and used fresh in Thai soups and curry pastes; human research is thin and limited to small trials of extracts.

  • Mental alertness and attention
  • Sexual function in men taking SSRI antidepressants
  • Sperm movement (combination product)
  • Knee osteoarthritis pain (with ginger)

More about Galangal

Turmeric

Warming and pungent roots and seeds

Curcuma longa

Rhizome

EarthyWarm / woodyBitter

Aroma: Earthy and a little like mustard, with a peppery warmth.

In the kitchen: curries, rice and grains, soups and stews, tea and drinks, vegetables

Turmeric is earthy, warm and slightly bitter and gives curries their yellow color; research on health uses is early, and concentrated curcumin products have been linked to liver injury.

  • Knee osteoarthritis pain and stiffness
  • Fatty liver disease measures
  • Mouth sores from cancer treatment
  • Mild digestion problems (traditional use)

More about Turmeric

Grains of paradise

Warming and pungent roots and seeds

Aframomum melegueta, Amomum melegueta (older name used in US regulations)

Seed

Hot / pungentCitrusyWarm / woody

Aroma: Peppery and warm, with a hint of citrus and cardamom.

In the kitchen: soups and stews, grilling and rubs, vegetables, tea and drinks, curries

Grains of paradise taste peppery with citrus and a touch of cardamom and are used in stews, rubs and drinks; trials of extracts are small and mostly company-linked, and we found no food-amount studies.

  • Belly fat and energy use
  • Anxiety, mood and sleep ratings
  • Blood glucose in rats

More about Grains of paradise

Mustard seed

Warming and pungent roots and seeds

Brassica nigra, Brassica juncea, Sinapis alba

Seed

Hot / pungentEarthy

Aroma: Almost none whole; a sharp, nose-tingling pungency once crushed and wetted.

In the kitchen: curries, pickling, grilling and rubs

Mustard seed is mild whole and sharply hot once crushed with liquid, used in curries, pickles and condiments; it is a strong allergen, and human research on health uses is very small.

  • Early cell-damage markers and cholesterol
  • Blood pressure, blood fats and blood sugar (glucosinolate foods)
  • Gum health (white mustard toothpaste)
  • Antimicrobial and anti-inflammatory activity in the lab

More about Mustard seed

Horseradish and wasabi

Warming and pungent roots and seeds

Armoracia rusticana, Eutrema japonicum

RootRhizome

Hot / pungentSour / tangyEarthy

Aroma: Almost no smell until cut, then a sharp, sinus-clearing sting.

In the kitchen: rice and grains, soups and stews, tea and drinks

Horseradish and wasabi are sharp, nose-clearing roots eaten fresh or as a paste; the heat fades fast, and the health research is thin, with one small memory trial on a wasabi extract.

  • Memory in healthy older adults (wasabi extract)
  • Acute bronchitis (nasturtium-horseradish combination)
  • Recurrent cystitis (nasturtium-horseradish combination)
  • Blood vessel lining function

More about Horseradish and wasabi

Black pepper

Hot peppers and peppercorns

Piper nigrum

Berry / fruit

Hot / pungentWarm / woodyCitrusy

Aroma: Sharp, woody and a little citrusy, with floral notes.

In the kitchen: grilling and rubs, soups and stews, vegetables

Black pepper is hot, warm and citrusy and goes in almost any savory dish; pepper on food is not a concern in the sources we read, but isolated piperine in supplements can change how medicines are absorbed.

  • Raises blood levels of curcumin
  • Cholesterol with curcumin (curcumin plus piperine)
  • Blood sugar, inflammation, nerves and cancer cells (lab work)
  • Colds, digestion, weight and pain

More about Black pepper

White pepper

Hot peppers and peppercorns

Piper nigrum

Berry / fruit

Hot / pungentEarthy

Aroma: Earthy and a little musty, with less of the citrus and pine of black pepper.

In the kitchen: soups and stews, vegetables, rice and grains, grilling and rubs

White pepper is hot, earthy and a little musty, used where black specks would show; no good human trials exist for food amounts, and isolated piperine supplements can change how medicines work.

  • Medicine absorption (isolated piperine)
  • Health uses of pepper in general
  • Traditional uses

More about White pepper

Pink peppercorn

Hot peppers and peppercorns

Schinus terebinthifolia (also spelled terebinthifolius), Schinus molle

Berry / fruit

SweetWarm / woody

Aroma: Slightly resinous, somewhere between black pepper and juniper, with no real heat.

In the kitchen: desserts, tea and drinks, pickling

Pink peppercorn is mild, nearly sweet and resinous and used in sauces, desserts and drinks; it comes from the cashew family, so people with cashew or pistachio allergy should check first, and no human trials of its health effects were found.

  • Blood sugar enzymes (lab and animal work)
  • Antioxidant activity of leaf extracts (lab only)
  • Antimicrobial and antiparasite activity of oils and extracts (lab only)
  • Any health use in people

More about Pink peppercorn

Long pepper

Hot peppers and peppercorns

Piper longum

Berry / fruit

Hot / pungentSweetWarm / woody

Aroma: Peppery and a little sweet, with hints of clove, nutmeg and pine, and a musky note when heated.

In the kitchen: curries, pickling, soups and stews

Long pepper is a peppery, slightly sweet spice used in pickles, lentil dishes and stews; its piperine can change how some medicines act, and there are no human trials of the spice itself.

  • Trikatu mix lowering a painkiller in animals
  • Liver-cell injury markers in a cell study
  • Traditional use in the Ayurvedic mix trikatu
  • Antimicrobial, antioxidant, anti-inflammatory and other lab activities

More about Long pepper

Sichuan (Szechuan) pepper

Hot peppers and peppercorns

Zanthoxylum bungeanum, Zanthoxylum simulans

Berry / fruit

CitrusyFloralHot / pungentWarm / woody

Aroma: Bright and floral, with citrus peel and a hint of pine.

In the kitchen: grilling and rubs, curries, soups and stews, vegetables

Sichuan pepper is citrusy and floral with a tingling, numbing feel and is used in Chinese cooking; human research on health is almost absent, and a few people are allergic.

  • Numbing and local pain relief (lab findings)
  • Cancer-related cell effects (lab and animal)
  • Anti-inflammatory, blood sugar and blood fat activity (genus review)
  • Any health use of the spice in food

More about Sichuan (Szechuan) pepper

Cayenne and chili pepper

Hot peppers and peppercorns

Capsicum annuum, Capsicum frutescens

Berry / fruit

Hot / pungentEarthyCitrusy

Aroma: Sharp and peppery, with a mild fruity or earthy note that changes by variety.

In the kitchen: curries, soups and stews, grilling and rubs, vegetables

Cayenne and chili pepper are hot and used in sauces, stews and curries; big studies of people who eat spicy food are observational, and chili can burn the gut, skin and eyes.

  • Pain relief on the skin (muscle pain)
  • Chronic nerve pain (high-strength skin patch)
  • Chronic nerve pain (low-strength cream)
  • Death from any cause and heart disease (food)

More about Cayenne and chili pepper

Cinnamon

Sweet and aromatic

Cinnamomum verum, Cinnamomum aromaticum (also called Cinnamomum cassia)

Bark

SweetWarm / woodyHot / pungent

Aroma: Warm, sweet and woody, with a gentle spicy bite.

In the kitchen: baking, desserts, curries, tea and drinks, rice and grains

Cinnamon is sweet, warm and woody and used in baking, curries and drinks; blood sugar research is mixed, and cassia cinnamon has a coumarin limit.

  • Blood sugar markers in type 2 diabetes
  • Blood fats (cholesterol, triglycerides)
  • Weight loss
  • Hay fever (Ceylon extract nasal spray)

More about Cinnamon

Cloves

Sweet and aromatic

Syzygium aromaticum, Eugenia caryophyllata (older name)

Flower bud

Warm / woodyHot / pungentEarthy

Aroma: Warm, strong and spicy-sweet, with a medicinal edge.

In the kitchen: baking, curries, rice and grains, tea and drinks, pickling

Cloves are warm, pungent and a little sweet and are used whole in rice, braises and drinks and ground in baking; research is mostly on clove oil, and the oil can poison young children.

  • Toothache and dental pain
  • Surface numbing before a needle in the mouth
  • Dry socket after tooth removal
  • Effects in cells and animals (infection, inflammation, cancer, others)

More about Cloves

Nutmeg

Sweet and aromatic

Myristica fragrans

Seed

Warm / woodySweetEarthy

Aroma: Warm, sweet and woody, with a pungent edge.

In the kitchen: baking, desserts, soups and stews, tea and drinks, vegetables

Nutmeg is warm, slightly sweet and used in baking, sauces and drinks; large amounts can poison people, and no trial supports a health benefit when eaten.

  • Painful diabetic nerve symptoms (skin product)
  • Antioxidant, antidiabetic and anticancer effects in cells and animals
  • Digestive use in traditional medicine

More about Nutmeg

Mace

Sweet and aromatic

Myristica fragrans

Aril (seed covering)

Warm / woodySweetHot / pungent

Aroma: Warm, sweet and lightly peppery, like nutmeg but sharper and more delicate.

In the kitchen: baking, desserts, curries, soups and stews

Mace is warm, sweet and a little peppery, used in baking, curries and pâtés; a pinch in food is normal, but large amounts of mace or nutmeg can poison.

  • Accepted as a seasoning
  • Painful diabetic nerve symptoms (skin product)
  • Digestive and other traditional uses

More about Mace

Allspice

Sweet and aromatic

Pimenta dioica

Berry / fruit

Warm / woodySweetHot / pungent

Aroma: Warm and sweet, a bit like clove, cinnamon and nutmeg together.

In the kitchen: baking, desserts, soups and stews, grilling and rubs, pickling

Allspice is warm and sweet, like cinnamon, clove and nutmeg in one berry, and is used in jerk, pickling and baking; human research on health is lacking, and the main caution is bleeding with large medicinal amounts.

  • Blood pressure (animal findings)
  • Antioxidant activity
  • Cell studies on cancer cell lines
  • Estrogen-like activity in cells

More about Allspice

Vanilla

Sweet and aromatic

Vanilla planifolia, Vanilla tahitensis

Pod / fruit

SweetFloralWarm / woody

Aroma: Sweet, creamy and warm, with floral, rum-like and slightly woody notes.

In the kitchen: baking, desserts, tea and drinks

Vanilla is sweet, creamy and floral and is used in baking, desserts and drinks; research on health benefits is thin and mostly from labs, and some cheap "vanilla" has been found to contain coumarin.

  • Health benefit from vanilla in food or extract
  • Antioxidant and pro-oxidant effects of vanillin
  • Nerve-cell protection in lab studies
  • Cancer-related effects of vanillin in lab studies

More about Vanilla

Star anise

Sweet and aromatic

Illicium verum

Berry / fruit

Licorice / aniseSweetWarm / woody

Aroma: Strong licorice scent, warm and a little sweet, like anise with a touch of clove.

In the kitchen: soups and stews, curries, baking, tea and drinks

Star anise tastes of licorice, warm and slightly sweet, and flavors soups, braises and baking; it must never be given to babies as tea, and one toxic look-alike has contaminated supplies.

  • Gum inflammation and mouth bacteria (mouthwash)
  • Source of shikimic acid for an antiviral flu medicine
  • Infant colic (traditional tea use)
  • Antimicrobial, antioxidant, pain-relief and sedative effects

More about Star anise

Cumin

Earthy and savory

Cuminum cyminum

Seed

EarthyWarm / woody

Aroma: Warm, earthy and slightly musky, and stronger after toasting.

In the kitchen: curries, soups and stews, pickling

Cumin is earthy and warm and a base of curries, chili and stews; trials of cumin supplements on blood sugar are mixed, and some people are allergic to it.

  • Fasting blood sugar markers
  • Blood cholesterol
  • Triglycerides and waist size
  • Traditional use for milk supply

More about Cumin

Fenugreek

Earthy and savory

Trigonella foenum-graecum

SeedLeaf

BitterEarthySweetWarm / woody

Aroma: Warm and sweet like maple syrup or caramel, with a curry-like note when strong.

In the kitchen: curries, pickling, vegetables, soups and stews, rice and grains

Fenugreek seed tastes bitter, earthy and a little like maple syrup and is used in curries, pickles and spice blends; it is not safe in pregnancy above food amounts, and blood sugar research is limited.

  • Blood sugar in type 2 diabetes and prediabetes
  • Cholesterol and blood fats
  • Breast milk supply
  • Menstrual cramps

More about Fenugreek

Asafoetida (hing)

Earthy and savory

Ferula assa-foetida, Ferula foetida

Resin

EarthyBitterHot / pungent

Aroma: Harsh and sulfurous in the jar, like onion and garlic; it turns mellow once cooked in hot oil.

In the kitchen: curries, soups and stews, rice and grains, pickling, vegetables

Asafoetida (hing) smells strong and sulfurous in the jar but cooks into a mellow onion-and-garlic flavor; it is unsafe for infants and discouraged in pregnancy, and human evidence for health uses is thin.

  • Irritable bowel symptoms
  • Irritable colon (1979 trial)
  • Gas, colic, blood pressure and other traditional uses

More about Asafoetida (hing)

Annatto (achiote)

Earthy and savory

Bixa orellana

Seed

EarthySweet

Aroma: Faint and earthy, with a light peppery note.

In the kitchen: grilling and rubs, soups and stews

Annatto is mild, earthy and a little peppery and is used mostly to turn food orange-red; allergy to it is rare but documented, and there is no good evidence of a health benefit from eating it.

  • Safety of annatto food color (daily limits set)
  • Blood fats and heart-risk markers
  • Feeling full after meals
  • Antioxidant and other effects of bixin

More about Annatto (achiote)

Curry leaf

Earthy and savory

Murraya koenigii, Bergera koenigii (current name in some sources)

Leaf

CitrusyEarthyBitter

Aroma: Bright and citrusy with a savory, slightly sulfury note when fried in oil.

In the kitchen: curries, soups and stews, rice and grains, vegetables

Curry leaf is citrusy, slightly bitter and savory and is fried in oil at the start of South Indian dishes; human research on blood sugar is one small 1990 study, and the rest is lab and animal work.

  • Blood sugar in type 2 diabetes
  • Blood sugar and blood fats in animals
  • Antioxidant and anti-inflammatory activity in the lab
  • Traditional use in Ayurvedic and Siddha medicine

More about Curry leaf

Bay leaf

Earthy and savory

Laurus nobilis

Leaf

EarthyFloral

Aroma: Herbal and slightly floral, a little like oregano and thyme.

In the kitchen: soups and stews, curries, rice and grains, desserts, tea and drinks

Bay leaf is herbal and slightly floral and simmered whole in soups, stews and curries, then removed; one small trial of capsules and one liver case report exist, so supplement use is unproven.

  • Blood sugar in type 2 diabetes
  • Blood fats (cholesterol and triglycerides)
  • Laboratory activity against cancer cells

More about Bay leaf

Black seed (nigella)

Earthy and savory

Nigella sativa

Seed

BitterEarthyHot / pungent

Aroma: Faintly herbal when raw; nutty, peppery and a little like onion and oregano once heated.

In the kitchen: baking, curries, pickling, vegetables, soups and stews

Black seed (nigella, kalonji) is peppery, bitter and a little onion-like, sprinkled on breads and tempered in oil for curries and pickles; blood pressure and blood sugar trials used supplements, and it may affect some medicines.

  • Blood pressure (small average fall)
  • Blood sugar (adults with metabolic disease)
  • Body weight and heart risk markers
  • Asthma, arthritis, digestion and fatty liver

More about Black seed (nigella)

Coriander seed

Seed spices

Coriandrum sativum

Seed

CitrusyWarm / woodyEarthy

Aroma: Warm and lemony, with a hint of orange peel.

In the kitchen: curries, pickling, grilling and rubs, soups and stews, baking

Coriander seed tastes warm and lemony and is used in curries, pickles and spice blends; one small diabetes trial is the main human evidence, and allergy is the main caution.

  • Blood sugar markers in type 2 diabetes
  • Cholesterol and triglycerides in type 2 diabetes
  • Migraine (syrup added to usual medicine)
  • Dyspepsia symptoms (two-herb capsule)

More about Coriander seed

Caraway

Seed spices

Carum carvi

Seed

Warm / woodyLicorice / aniseSweet

Aroma: Warm, sharp and slightly sweet, a bit like anise.

In the kitchen: baking, soups and stews, vegetables, tea and drinks

Caraway is warm, gently sweet and a little like anise, and is used in rye bread, sauerkraut and stews; a peppermint-and-caraway oil capsule helped indigestion in trials, and people allergic to birch, mugwort or celery may react to it.

  • Indigestion symptoms (with peppermint oil)
  • Bloating and gas (traditional use)
  • Breast milk supply
  • Infant colic (mother takes caraway)

More about Caraway

Anise (aniseed)

Seed spices

Pimpinella anisum

Seed

Licorice / aniseSweetWarm / woody

Aroma: Sweet and strongly licorice-like, a little like fennel.

In the kitchen: baking, desserts, tea and drinks, soups and stews

Anise (aniseed) is sweet with a clear licorice taste and is used in baking, sweets and drinks; research on digestion and IBS comes from small trials of anise oil, and it is not star anise.

  • Mild indigestion, bloating and gas (traditional tea use)
  • Irritable bowel syndrome symptoms (anise oil capsules)
  • Functional dyspepsia
  • Depression symptoms in people with IBS (anise oil)

More about Anise (aniseed)

Fennel seed

Seed spices

Foeniculum vulgare

Seed

Licorice / aniseSweetWarm / woody

Aroma: Sweet and fresh, like anise or licorice but milder.

In the kitchen: curries, baking, tea and drinks

Fennel seed is sweet and anise-like and used in sausages, breads, curries and spice blends; infant colic trials look promising but limited, and EU regulators set estragole limits for children and pregnancy.

  • Infant colic
  • Mild gas and bloating in adults
  • Period pain
  • Cough with a cold

More about Fennel seed

Celery seed

Seed spices

Apium graveolens

Seed

EarthyBitter

Aroma: Strong, green and celery-like, with a slightly citrusy edge.

In the kitchen: pickling, vegetables, soups and stews, grilling and rubs, tea and drinks

Celery seed is earthy and slightly bitter and used in pickles, slaws and celery salt; small trials suggest blood pressure effects from supplements, and celery allergy can be severe.

  • Blood pressure
  • Triglycerides and fasting glucose
  • Metabolic syndrome markers
  • Uric acid and gout (animals)

More about Celery seed

Dill seed

Seed spices

Anethum graveolens

Seed

EarthyWarm / woodyCitrusy

Aroma: Fresh, a little citrusy and like caraway, stronger than the leafy herb.

In the kitchen: pickling, baking, soups and stews, vegetables

Dill seed tastes like a stronger, warmer cousin of caraway and is used in pickles and breads; small supplement trials on cholesterol are mixed, and food amounts have not been tested.

  • LDL cholesterol
  • Insulin and insulin resistance
  • Period pain
  • Length of labor

More about Dill seed

Trachyspermum ammi, Carum copticum (older name)

Seed

BitterHot / pungentEarthy

Aroma: Strongly thyme-like, with an oregano and anise edge.

In the kitchen: baking, curries, tea and drinks

Ajwain (carom seed) is sharp, bitter and thyme-like and is fried in oil for breads and tarka; research is limited, and its oil is strong and not for swallowing.

  • Burning foot pain (nerve pain), skin cream
  • Nerve symptoms after chemotherapy
  • Pain before dental injections in children
  • Germ-fighting and antioxidant activity in the lab

More about Ajwain (carom seed)

Saffron

Floral, citrus and tangy

Crocus sativus

Flower stigma

FloralSweetBitter

Aroma: Hay-like and honeyed, floral, with a faint medicinal edge.

In the kitchen: rice and grains, soups and stews, desserts, tea and drinks, baking

Saffron is floral, honey-like and slightly bitter and gives rice and stews a golden color; trials of supplements suggest lower self-rated low mood, but cooking amounts are not studied and fakes are common.

  • Self-rated depression and anxiety scores
  • Compared with SSRI antidepressants
  • Blood sugar, blood pressure and cholesterol markers
  • Labor and pregnancy outcomes

More about Saffron

Cardamom

Floral, citrus and tangy

Elettaria cardamomum

SeedPod / fruit

SweetFloralWarm / woody

Aroma: Sweet, resinous and perfumed, with a cool eucalyptus note.

In the kitchen: baking, desserts, tea and drinks, rice and grains, curries

Cardamom is sweet, floral and a little cooling and used in chai, baking and rice; trials of supplements show small changes in blood fats, and people with gallstones should keep to food amounts.

  • Blood fats (triglycerides and cholesterol)
  • Inflammation markers
  • Blood pressure
  • Nausea after surgery (oil on ice cubes)

More about Cardamom

Sumac

Floral, citrus and tangy

Rhus coriaria

Berry / fruit

Sour / tangyCitrusyEarthy

Aroma: Mild and fruity, with a slight earthiness.

In the kitchen: grilling and rubs, vegetables, rice and grains, tea and drinks

Sumac is a tart, lemony red spice sprinkled on salads, dips and grilled meat; trials on blood sugar are mixed, and people with a cashew allergy should check first.

  • Blood sugar markers
  • Diastolic blood pressure
  • Blood fats (cholesterol, triglycerides)
  • Inflammation markers

More about Sumac

Tamarind

Floral, citrus and tangy

Tamarindus indica

Fruit pulp

Sour / tangySweet

Aroma: Fruity and tangy, like sour dried fruit.

In the kitchen: curries, soups and stews, tea and drinks, pickling, rice and grains

Tamarind is sweet and sour and is used in curries, chutneys, soups and drinks; the one trial we read found no effect on weight or blood sugar, and one small study found it raised aspirin absorption.

  • Weight, blood fats, blood sugar and blood pressure
  • Blood sugar in diabetes
  • Traditional laxative use
  • Other folk uses (fever, sore throat, dysentery, parasites)

More about Tamarind

Juniper berry

Floral, citrus and tangy

Juniperus communis

Berry / fruit

EarthyCitrusyWarm / woody

Aroma: Fresh and resinous like pine needles, with a lift of citrus.

In the kitchen: soups and stews, grilling and rubs, pickling, tea and drinks

Juniper berry tastes piney and resinous with a citrus note and is used with game, pork and cabbage; the EU accepts it only for traditional use, and it is not advised in pregnancy or severe kidney disease.

  • Functional dyspepsia (upper-stomach discomfort)
  • Period pain (primary dysmenorrhea)
  • Traditional use to flush the urinary tract
  • Traditional use for indigestion and gas

More about Juniper berry

Paprika

Paprika, chili and smoky

Capsicum annuum

Berry / fruit

SweetHot / pungent

Aroma: Mild and sweet, a little like dried red pepper; smoked types smell of wood smoke.

In the kitchen: soups and stews, grilling and rubs, rice and grains, vegetables

Paprika is a mild, sweet, red spice from dried peppers that colors and gently flavors stews, rice and rubs; research on it is thin, and some imported powders have had contamination problems.

  • Source of red carotenoid pigments (capsanthin)
  • Exercise efficiency and thinking tests (pigment extract)
  • Heart and vessel disease in spicy-food eaters
  • Colour additive intake and diabetes risk (association)

More about Paprika

Smoked paprika (pimentón)

Paprika, chili and smoky

Capsicum annuum

Berry / fruit

SmokySweetWarm / woody

Aroma: Wood smoke over mild, sweet dried red pepper.

In the kitchen: soups and stews, rice and grains, grilling and rubs

Smoked paprika (pimentón) tastes of wood smoke with mild pepper sweetness and is used in stews, rice and rubs; smoking leaves PAH residues that vary a lot, and research on health benefits is very thin.

  • Small share of total PAH intake in Spain
  • Cholesterol and antioxidant markers (rats)

More about Smoked paprika (pimentón)

Garam masala

Spice blends

Blend of spices; no single species (typically includes Elettaria cardamomum, Cuminum cyminum, Coriandrum sativum, Cinnamomum spp., Syzygium aromaticum, Piper nigrum, Myristica fragrans)

Warm / woodySweetEarthyHot / pungent

Aroma: Warm and sweet, with floral cardamom, earthy cumin and a gentle peppery bite.

In the kitchen: curries, soups and stews, grilling and rubs, vegetables, rice and grains

Garam masala is a warm, sweet and earthy Indian spice blend added late to curries and stews; it is rarely studied as a blend, and its health points come from the spices in it.

  • Health effects of the blend as a whole

More about Garam masala

Curry powder

Spice blends

Spice blend (no single species)

Warm / woodyEarthyHot / pungent

Aroma: Warm, earthy and savory, with a little heat.

In the kitchen: curries, soups and stews, rice and grains, vegetables

Curry powder is a warm, earthy, golden blend for curries and stews; blends are rarely studied as a whole, so check the label for salt and allergens such as mustard, celery or sesame.

  • Health effects of curry powder as a blend

More about Curry powder

Za'atar

Spice blends

Origanum syriacum (wild za'atar herb), Thymus spp., Rhus coriaria, Sesamum indicum

EarthySour / tangyCitrusy

Aroma: Herby and earthy like thyme and oregano, with a toasted, nutty note from sesame and a lemony hint.

In the kitchen: baking, grilling and rubs, vegetables, rice and grains

Za'atar is a tangy, herby, nutty Middle Eastern blend of thyme or oregano, sumac, sesame and salt; it is rarely studied as a blend, and sesame is a major allergen.

  • Thyme medicines for chesty cough (traditional use)
  • Antioxidant and antimicrobial activity of Origanum syriacum

More about Za'atar

Chinese five-spice

Spice blends

Illicium verum, Syzygium aromaticum, Cinnamomum cassia, Zanthoxylum spp., Foeniculum vulgare

Warm / woodyLicorice / aniseSweet

Aroma: Sweet and warm, with a strong anise-licorice note and a little clove.

In the kitchen: grilling and rubs, soups and stews

Chinese five-spice is a sweet, warm, anise-scented blend used on duck, pork and in braises; it is rarely studied as a blend, and its cassia and star anise parts carry specific cautions.

  • Antioxidant capacity in a laboratory measure
  • Traditional use for indigestion and as an antiseptic

More about Chinese five-spice

Ras el hanout

Spice blends

Blend of many spices; no single species

Warm / woodySweetEarthyFloral

Aroma: Intensely fragrant, warm and complex, with sweet spice and a hint of flowers.

In the kitchen: soups and stews, grilling and rubs, rice and grains, desserts

Ras el hanout is a warm, sweet and earthy North African blend of a dozen or more spices for stews, rubs and couscous; it is rarely studied as a blend, and labels are worth reading for allergens.

  • Health effects of the blend as a whole

More about Ras el hanout

Herbes de Provence

Spice blends

Blend of Thymus vulgaris, Satureja species, Salvia rosmarinus, Origanum vulgare and O. majorana; sometimes Lavandula angustifolia

EarthyWarm / woodyFloral

Aroma: Piney and herbal, with warm, resinous notes and sometimes a soft floral hint from lavender.

In the kitchen: grilling and rubs, vegetables, soups and stews

Herbes de Provence is an earthy, piney dried-herb blend for grilled meat, fish and vegetable stews; it is rarely studied as a blend, and the herbs in it carry mint-family allergy and medicine cautions at supplement level.

  • Thyme for chesty coughs with colds (traditional use)

More about Herbes de Provence

Baharat

Spice blends

Blend of spices; no single species (often Piper nigrum, Cinnamomum spp., Syzygium aromaticum, Pimenta dioica, Cuminum cyminum, Coriandrum sativum)

Warm / woodySweetHot / pungent

Aroma: Warm and sweet like cinnamon and cloves, with a peppery edge.

In the kitchen: grilling and rubs, soups and stews, vegetables

Baharat is a warm, sweet and peppery Middle Eastern spice blend for meat, soups and vegetables; it is rarely studied as a blend, so health facts come from its single spices.

  • Blend not studied for health effects

More about Baharat

Berbere

Spice blends

Spice blend (no single species), Capsicum spp. (chili base), Trigonella foenum-graecum (fenugreek), Aframomum corrorima (korarima)

Hot / pungentWarm / woodyEarthy

Aroma: Fiery and warm, with sweet spice and a hint of maple from fenugreek.

In the kitchen: soups and stews, grilling and rubs, vegetables

Berbere is a hot, warm and earthy Ethiopian and Eritrean chili blend used in stews and rubs; it has not been studied as a blend, and its fenugreek brings a legume-allergy and pregnancy caution.

  • Chili intake and health outcomes (main ingredient)
  • Fenugreek and blood sugar (component evidence)

More about Berbere

Dukkah

Spice blends

Blend of nuts, seeds and spices; no single species

EarthyWarm / woodyCitrusy

Aroma: Toasty and nutty, with earthy cumin and a light citrus note from coriander.

In the kitchen: vegetables, grilling and rubs, soups and stews

Dukkah is a crunchy, nutty, toasty Egyptian blend of nuts, sesame, cumin and coriander for dipping with bread and oil; it is rarely studied as a blend, and nuts and sesame make it an allergy food.

  • Nuts and blood fats (whole nuts, not the blend)
  • Health effects of dukkah as a whole

More about Dukkah

Chili powder

Spice blends

Spice blend (no single species); chile is Capsicum spp.

EarthyWarm / woodyHot / pungent

Aroma: Earthy and savory, with a garlic note and a little warmth from the chile.

In the kitchen: soups and stews, grilling and rubs, curries

Chili powder is an earthy, savory, mildly hot blend for chili, tacos and rubs; the blend itself is not studied for health, but check the label for salt and allergens, and note that some ground chili has tested high in lead.

  • Health effects of chili powder as a blend

More about Chili powder

Pumpkin pie spice

Spice blends

Blend: Cinnamomum spp., Zingiber officinale, Myristica fragrans, Syzygium aromaticum, Pimenta dioica

Warm / woodySweet

Aroma: Warm and sweet, led by cinnamon, with sharp clove and a soft nutty note from nutmeg.

In the kitchen: baking, desserts, tea and drinks

Pumpkin pie spice is a warm, sweet blend of cinnamon, ginger, nutmeg and cloves used in pies, baking and coffee drinks; it is not studied as a blend, and its cautions come from cassia coumarin, large amounts of nutmeg and lead in some ground spices.

  • Health effects of the blend as a whole

More about Pumpkin pie spice

Spice blend (no single species)

Hot / pungentEarthyWarm / woody

Aroma: Savory and peppery, with garlic, paprika and a little heat.

In the kitchen: grilling and rubs, soups and stews, rice and grains, vegetables

Cajun and Creole seasoning is a salty, peppery, garlicky blend with cayenne heat for meat, seafood and rice; the blend itself is not studied for health, and salt content varies widely by brand.

  • Health effects of Cajun seasoning as a blend

More about Cajun and Creole seasoning

Spice blend (no single species)

Hot / pungentWarm / woodySweet

Aroma: Warm and spicy like allspice and thyme, with a fruity chili edge.

In the kitchen: grilling and rubs, vegetables

Jamaican jerk seasoning is hot, warm and sweet, built on allspice and scotch bonnet chili for grilled meat; the blend itself is not studied for health, so check the label for salt and allergens and handle the chilies with care.

  • Health effects of jerk seasoning as a blend

More about Jamaican jerk seasoning

Panch phoron

Spice blends

Blend of five seeds, no single species (Trigonella foenum-graecum, Cuminum cyminum, Nigella sativa, Brassica nigra, Foeniculum vulgare)

EarthyBitterLicorice / anise

Aroma: A mixed seed smell that turns toasty and fragrant when the seeds sizzle in oil.

In the kitchen: curries, pickling, vegetables, soups and stews

Panch phoron is a Bengali blend of five whole seeds, fried in hot oil at the start of a dish; it is not studied as a blend, so health facts come from its seeds, and mustard and fenugreek can cause allergy.

  • Fenugreek and blood sugar
  • Blend not studied for health effects

More about Panch phoron

Chaat masala

Spice blends

Blend: Mangifera indica (amchoor), Cuminum cyminum, Coriandrum sativum, Piper nigrum, Zingiber officinale, Ferula assa-foetida, plus salt

Sour / tangyEarthyHot / pungent

Aroma: Sharp and savory, with a sulfur note from black salt and a fruity tang from dried mango.

In the kitchen: vegetables, tea and drinks, rice and grains

Chaat masala is a tangy, salty, savory blend sprinkled on street snacks, fruit and yogurt; it is rarely studied as a blend, and its main limits are the salt it contains and the allergens on the label.

  • Traditional use of black salt for digestion

More about Chaat masala

Shichimi togarashi

Spice blends

Blend of spices; no single species (typically Capsicum annuum, Zanthoxylum piperitum, Sesamum indicum, Zingiber officinale)

Hot / pungentCitrusyEarthy

Aroma: Chili heat with a bright orange-peel note and a toasted, nutty background.

In the kitchen: soups and stews, rice and grains, grilling and rubs, vegetables

Shichimi togarashi is a Japanese chili blend that is hot, citrusy and nutty, sprinkled on noodles and rice at the table; it has not been studied as a blend, and it can contain sesame and poppy seed.

  • Spicy food and chili, general health
  • Blend not studied for health effects

More about Shichimi togarashi

Amchur (dried green mango powder)

Floral, citrus and tangy

Mangifera indica

Berry / fruit

Sour / tangyCitrusySweet

Aroma: Fruity and a little honey-like, with a sharp tang.

In the kitchen: curries, vegetables, soups and stews, grilling and rubs, pickling

Amchur is a tart, fruity powder from dried green mango used to sour curries and vegetables; there are no human trials on it, and mango allergy or sulfite sensitivity are the main cautions.

  • Blood sugar and blood fats (mango in other forms)
  • Early insulin resistance and liver fat (mice)
  • Any health use of amchur in food amounts

More about Amchur (dried green mango powder)

Kokum

Floral, citrus and tangy

Garcinia indica

Berry / fruit

Sour / tangySweet

Aroma: Mainly sour and tangy; we found no source that describes its smell.

In the kitchen: curries, soups and stews, tea and drinks, rice and grains

Kokum is a very sour dried fruit rind used in place of tamarind in Indian curries and drinks; nearly all health research is in labs and animals, and its cousin Garcinia cambogia supplements have liver-injury reports.

  • Chronic gastritis symptoms
  • Weight and fat metabolism
  • Antioxidant and anti-inflammatory activity
  • Heart protection

More about Kokum

Mahlab (mahleb)

Sweet and aromatic

Prunus mahaleb, Cerasus mahaleb (synonym)

Seed

SweetBitterFloral

Aroma: Almond and cherry, a little like marzipan.

In the kitchen: baking, desserts

Mahlab is a cherry-stone spice that tastes of bitter almond and cherry and is used in sweet breads and pastries; it contains coumarin, and no study of it as a food or supplement was found.

  • No human trial found
  • Antioxidant and anti-inflammatory effects (reported, untested)
  • Other uses in people (pregnancy, medicines, allergy)

More about Mahlab (mahleb)

Grains of Selim

Warming and pungent roots and seeds

Xylopia aethiopica

Berry / fruit

Hot / pungentWarm / woodyBitter

Aroma: Resinous and woody, often compared to cubeb pepper mixed with nutmeg, with a smoky note when dried over fire.

In the kitchen: soups and stews, grilling and rubs, tea and drinks, rice and grains

Grains of Selim are peppery, resinous and a little bitter and used in West African soups, sauces and coffee; we found no human studies, and rat studies hint at lower platelet counts with long, high use.

  • Pain and inflammation in animals
  • Anxiety-like behavior in mice
  • Cancer cell growth in the lab

More about Grains of Selim

Ancho chile

Paprika, chili and smoky

Capsicum annuum (dried poblano)

Berry / fruit

SweetEarthyWarm / woody

Aroma: Dried-fruit, raisin-like and a little tobacco-like when fresh; it fades as the pod ages.

In the kitchen: soups and stews, grilling and rubs

Ancho chile is mild, fruity and earthy and the base of many Mexican sauces; research on chili is mixed, and the evidence mostly covers hotter chilies and extracts.

  • Muscle pain (skin plaster or gel)
  • Heart and all-cause death in people who eat spicy food
  • Overall health effects of spicy food
  • Digestive symptoms

More about Ancho chile

Chipotle (smoked jalapeno)

Paprika, chili and smoky

Capsicum annuum

Berry / fruit

SmokyEarthyHot / pungent

Aroma: Smoky and woody, with an earthy depth behind the heat.

In the kitchen: grilling and rubs, soups and stews, vegetables, rice and grains

Chipotle is smoky, earthy and medium-hot and used in salsas, marinades and stews; research on chili food is mostly observational, and the heat can irritate the gut and skin.

  • Death from any cause and heart disease (spicy food)
  • Nerve pain (high-strength skin patch)
  • Stomach symptoms (dyspepsia, reflux, IBS)
  • Digestive-tract cancer risk (chili food, case-control)

More about Chipotle (smoked jalapeno)

Aleppo pepper

Paprika, chili and smoky

Capsicum annuum

Berry / fruit

Hot / pungentSweetEarthy

Aroma: Fruity and raisin-like, with a faint cumin note.

In the kitchen: vegetables, soups and stews, grilling and rubs

Aleppo pepper is mildly hot, fruity and slightly salty and used as a flake in Turkish and Middle Eastern cooking; studies of chili eaters are observational, and chili can burn the gut, skin and eyes.

  • Death from any cause and heart disease (food)
  • Digestive-tract cancer risk (food, case-control)
  • Stomach symptoms (dyspepsia, reflux, IBS)
  • Weight, appetite and blood pressure

More about Aleppo pepper

Kashmiri chili

Paprika, chili and smoky

Capsicum annuum

Berry / fruit

SweetHot / pungentSmoky

Aroma: Fruity and a little smoky, like a mild dried red pepper.

In the kitchen: curries, grilling and rubs, pickling

Kashmiri chili is a mild, fruity, deep-red chili used mostly for colour in Indian curries and tandoori dishes; research on chili in general is mixed, and cheap red powders are sometimes dyed.

  • Heart-related and all-cause death in spicy-food eaters
  • Nerve pain from the skin (prescription 8% capsaicin patch)
  • Overall health outcomes of spicy food
  • Blood sugar, appetite and blood pressure (capsaicin)

More about Kashmiri chili

Cubeb pepper

Hot peppers and peppercorns

Piper cubeba

Berry / fruit

Hot / pungentWarm / woodyBitter

Aroma: Dry, woody and warm, with a camphor-like, peppery edge.

In the kitchen: curries, soups and stews, baking, tea and drinks

Cubeb pepper is pungent, warm and a little bitter and used in North African and Indonesian cooking; almost nothing is known about its health effects in people, and lab work hints at drug interactions.

  • Anti-inflammatory and antioxidant effects (cells and animals)
  • Blood sugar-related enzyme blocking (lab only)
  • Antibacterial and antifungal activity (lab only)
  • Kidney disease: one case report

More about Cubeb pepper

Makrut (kaffir) lime leaf

Floral, citrus and tangy

Citrus hystrix

Leaf

CitrusyFloralSweet

Aroma: Bright, floral and lemony, like perfumed lime.

In the kitchen: curries, soups and stews

Makrut (kaffir) lime leaf is floral, lemony and fragrant and flavors Thai and Southeast Asian curries and soups; human health research on the leaf is missing, and the fruit's juice and peel can cause skin reactions in sunlight.

  • Blood sugar (lab and rat studies)
  • Blood pressure (lab and rat studies)
  • Cholesterol and weight
  • Germ-fighting in the lab

More about Makrut (kaffir) lime leaf

Cinnamomum tamala

Leaf

Warm / woodySweetHot / pungent

Aroma: Mild cinnamon-like and clove-like, warm, with a faint peppery note.

In the kitchen: curries, rice and grains, soups and stews

Indian bay leaf (tej patta) tastes like mild cinnamon with a clove-like edge and is used in North Indian and Mughal-style cooking; we found no human trials, so health claims rest on lab and animal work.

  • Blood sugar (animal studies only)
  • Diarrhoea (rat study)
  • Germ-killing action in the lab
  • Antioxidant activity in lab tests

More about Indian bay leaf (tej patta)

Black cardamom

Warming and pungent roots and seeds

Amomum subulatum

Pod / fruitSeed

SmokyEarthyWarm / woody

Aroma: Smoky and resinous, with a cool camphor note.

In the kitchen: curries, rice and grains, soups and stews

Black cardamom is smoky, camphor-like and earthy and used in rice, curries and stews; research on it is almost all lab or animal work, with no human trials found.

  • Stomach lining protection (rats)
  • Blood fats (animals)
  • Antioxidant, anti-inflammatory and germ-fighting effects (lab)
  • Traditional digestive use

More about Black cardamom

Poppy seed

Seed spices

Papaver somniferum

Seed

EarthyBitterSweet

Aroma: Mild, earthy and musty when whole; ground seeds smell smoky and sweet.

In the kitchen: baking, desserts, curries, rice and grains

Poppy seed is nutty, earthy and slightly bitter and used in baking, fillings and curries; the seeds can carry traces of opium alkaloids, which matters for drug tests, poppy seed tea and young children.

  • Effect of heat on alkaloids
  • Minerals and fiber in the seed

More about Poppy seed

Sesame seed

Seed spices

Sesamum indicum

Seed

EarthySweetWarm / woody

Aroma: Mild and nutty when raw; toasting brings out a deeper, roasted smell.

In the kitchen: baking, desserts, rice and grains, vegetables

Sesame seed is nutty and rich, especially when toasted, and used in breads, sweets, tahini and stir-fries; it is a major allergen, and the small blood pressure and cholesterol trials are weak.

  • Blood pressure (small trials of sesame products)
  • Blood sugar markers (HbA1c)
  • Cholesterol and triglycerides
  • Inflammation markers (CRP, IL-6)

More about Sesame seed

Dried black lime (loomi)

Floral, citrus and tangy

Citrus aurantiifolia

Berry / fruit

Sour / tangyEarthySmokyCitrusy

Aroma: Sharp lime scent with a dark, smoky, slightly fermented edge.

In the kitchen: soups and stews, rice and grains, tea and drinks

Dried black lime (loomi) is sour, earthy and smoky and used to sour stews, soups and rice; research is lab-only, and lime juice has a lab link to medicine-processing enzymes.

  • Antioxidant activity in the lab
  • Starch-digesting enzyme blocked in the lab
  • Traditional tea for upset stomach, nausea, diarrhea

More about Dried black lime (loomi)

Trigonella foenum-graecum

Leaf

BitterEarthySweet

Aroma: Strong and pungent in the jar, with a nutty, maple-like sweetness that softens in the pot.

In the kitchen: curries, soups and stews, baking, vegetables

Dried fenugreek leaf (kasuri methi) tastes earthy, nutty and slightly bitter and finishes curries and breads; the research is mostly on the seed, and larger medicinal amounts are not advised in pregnancy.

  • Blood sugar in type 2 diabetes and prediabetes
  • Cholesterol and blood fats
  • Breast milk supply
  • Menstrual cramps

More about Dried fenugreek leaf (kasuri methi)

Garlic powder

Earthy and savory

Allium sativum

Bulb

EarthyHot / pungent

Aroma: Savory and sulfury, like cooked garlic but flatter and drier.

In the kitchen: grilling and rubs, soups and stews, vegetables, rice and grains

Garlic powder is savory, pungent and mellow and used in rubs, sauces and spice blends; research on cholesterol and blood pressure is for supplements, not for a pinch in food, and supplements may raise bleeding risk.

  • Small effect on total and LDL cholesterol
  • Small effect on blood pressure
  • Small effect on blood sugar
  • Colds and immune function

More about Garlic powder

Onion powder

Earthy and savory

Allium cepa

Bulb

EarthyHot / pungent

Aroma: Savory and sulfury, like cooked onion but drier and more concentrated.

In the kitchen: grilling and rubs, soups and stews, vegetables, rice and grains

Onion powder is savory and sharp and used in rubs, soups and sauces; no study tested the powder itself, and onion can upset some people with IBS.

  • Blood pressure (quercetin supplements)
  • Body weight and waist size
  • Blood sugar and blood fats
  • Cancer risk

More about Onion powder

Carthamus tinctorius

Flower

Earthy

Aroma: Very little; the petals have almost no smell of their own.

In the kitchen: rice and grains, soups and stews, tea and drinks

Safflower petals ("false saffron") give food a golden color but almost no saffron flavor; human research on the flower is thin, and bleeding, pregnancy and daisy-family allergy are the cautions.

  • Heart and circulation (Chinese products)
  • Platelet and clotting effects in the laboratory
  • Cancer, liver and brain protection
  • Reproductive safety of a food-grade extract

More about Safflower ("false saffron")

Dried citrus peel

Floral, citrus and tangy

Citrus sinensis, Citrus × aurantium, Citrus reticulata, Citrus limon

Berry / fruit

CitrusyBitterSweet

Aroma: Fresh and zesty like orange oil, turning deeper and richer in aged peel.

In the kitchen: baking, desserts, tea and drinks, soups and stews

Dried citrus peel is bright, aromatic and a little bitter and is used in baking, drinks, stews and teas; the peel itself is little studied, and Seville orange peel can affect some medicines like grapefruit does.

  • Blood fats and blood pressure (hesperidin)
  • Gut and metabolic health (orange peel ingredients)
  • Indigestion (chenpi formulas)

More about Dried citrus peel

Tonka bean

Sweet and aromatic

Dipteryx odorata

Seed

SweetWarm / woodyFloral

Aroma: Sweet and hay-like, with notes of vanilla, almond, cherry and a little clove.

In the kitchen: desserts, baking, tea and drinks

Tonka bean is sweet, warm and vanilla-like and is grated into desserts; no health benefit has been shown, and in the US it is not allowed in food because of its coumarin.

  • Health benefits of tonka bean

More about Tonka bean

Mastic (mastiha)

Floral, citrus and tangy

Pistacia lentiscus

Resin

EarthyBitter

Aroma: Fresh and resinous, like pine, with a woody, slightly musky and vanilla-like depth.

In the kitchen: desserts, baking, tea and drinks

Mastic is a pine-like, slightly sweet resin used in Greek and Middle Eastern sweets, breads and drinks; small trials on indigestion are promising but limited, and it is not advised in pregnancy.

  • Indigestion without a known cause
  • H. pylori infection
  • Total cholesterol and fasting glucose markers
  • Traditional use for mild indigestion and minor skin problems

More about Mastic (mastiha)

Sassafras albidum

Leaf

EarthyWarm / woody

Aroma: Earthy and herbal, with a faint spicy note.

In the kitchen: soups and stews

Filé powder is earthy and slightly herbal and is stirred into gumbo at the end to thicken it; sassafras root and oil carry a safrole warning, and the one lab test we found found little or none in the leaves.

  • Safrole level in filé leaf powder
  • Lab blocking of liver enzymes by safrole
  • Pregnancy and breastfeeding
  • Any health benefit of filé

More about Filé powder (ground sassafras leaf)

Lovage seed

Seed spices

Levisticum officinale

Seed

EarthyLicorice / aniseWarm / woody

Aroma: Celery-like and herbal, with a faint anise note.

In the kitchen: pickling, soups and stews, vegetables

Lovage seed tastes like celery and parsley with a hint of anise and is used like fennel seed in pickles and breads; almost no research exists on the seed, and the root has sun-sensitivity and kidney cautions.

  • Urinary flushing (traditional, root)
  • Inflammation markers in cells
  • Memory in rats
  • Metabolic syndrome enzymes (test tube)

More about Lovage seed

A link between a spice and a topic means the body needs the spice for that job, or that low intake is linked to it. It does not mean extra supplements help if your intake is already adequate. See each page’s evidence label.

Browse by spice flavor family

Sweet and aromatic

Cinnamon, cloves, nutmeg, vanilla and relatives: the warm, sweet smells of baking, mulled drinks and festive dishes.

Warming and pungent roots and seeds

Ginger, turmeric, galangal and mustard: underground stems and seeds with a warm bite.

Hot peppers and peppercorns

Chili and the peppercorns, from gentle pink pepper to fiery cayenne and tingling Sichuan pepper.

Seed spices

Coriander, fennel, caraway, dill and kin: small seeds with fresh, anise-like or citrusy aromas.

Paprika, chili and smoky

Paprika, smoked paprika, ancho, chipotle, Aleppo and Kashmiri chili: sweet, mild or smoky red peppers that color and flavor food.

Spice blends

Garam masala, curry powder, za’atar, five-spice and more: mixes of several spices. Contents vary by maker, so health findings for one spice do not carry over to a blend.

Related minerals, nutrients and supplements

Spices work alongside other nutrients. Here is what our sources link to them.

  • Beta-carotene

    Vitamin A: The body can convert beta-carotene to vitamin A.

  • Vitamin E

    Vitamin A: Vitamin E and beta-carotene were tested together in the Finnish smoker trial.

  • Calcium

    Vitamin D: Vitamin D increases calcium absorption; both matter for bones, and treatment of rickets and osteomalacia includes both.

  • Phosphorus

    Vitamin D: NHS says vitamin D helps regulate calcium and phosphate.

  • Vitamin K

    Vitamin E: MedlinePlus says vitamin E helps the body use vitamin K; both affect blood clotting, which matters for people on blood thinners.

  • Selenium

    Vitamin E: Vitamin E and selenium were tested together and apart in the SELECT prostate cancer trial.

  • Vitamin C

    Vitamin E: Vitamin C and vitamin E were pooled with other antioxidants in the Cochrane mortality review.

  • Vitamin D

    Vitamin K: Vitamin D with K2 products exist; the site page does not claim an added benefit.

  • Folate

    Vitamin B1 (thiamin): The NHS page covers B vitamins together; MedlinePlus says doctors may recommend other vitamins alongside thiamin for beriberi.

  • Other B vitamins

    Vitamin B2: MedlinePlus says riboflavin works with the other B vitamins.

  • Tryptophan

    Vitamin B3 (niacin): Pellagra comes from too little niacin or tryptophan in the diet, so both matter for avoiding deficiency.

  • Biotin

    Vitamin B5: MedlinePlus covers pantothenic acid and biotin together; both are needed for growth and metabolism and for making fatty acids.

HerbsOmega fatty acidsAntioxidantsSupplement formulasCompare supplementsNatural Remedy Safety

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Explore Spices

Understanding Spices(6)What spices are, how to read flavor and aroma, how to buy and store them, how blends work, and how food amounts differ from supplements.
Sweet & Aromatic Spices(9)Cinnamon, cloves, nutmeg, mace, allspice, vanilla, star anise, mahlab and tonka bean: warm, sweet-smelling spices for baking, desserts and mulled drinks.
Warming & Pungent Spices(8)Ginger, turmeric, galangal, grains of paradise, grains of Selim, black cardamom, mustard and horseradish: roots, pods and seeds with a warm bite.
Hot Peppers & Peppercorns(7)Black, white, pink, long, cubeb and Sichuan pepper, plus cayenne and chili: from gentle to fiery.
Earthy & Savory Spices(13)Cumin, fenugreek, asafoetida, annatto, curry leaf, bay leaf, black seed, garlic and onion powder and more: deep notes for curries, stews and beans.
Seed Spices(10)Coriander, caraway, anise, fennel, celery, dill, ajwain, poppy, sesame and lovage seed: small seeds with fresh, anise-like, nutty or citrusy aromas.
Floral, Citrus & Tangy Spices(11)Saffron, cardamom, sumac, tamarind, juniper, amchur, kokum, citrus peel, lime leaf and mastic: perfumed, lemony or sour accents.
Paprika, Chili & Smoky Spices(6)Sweet, hot and smoked paprika, ancho, chipotle, Aleppo and Kashmiri chili: red peppers that color and flavor food.
Spice Blends(16)Garam masala, curry powder, za'atar, five-spice, ras el hanout and other blends: what is usually in them, how they are used, and what a blend means for health.

Search spices: popular spices, A to Z, search with filters, more ways

Health benefits of spices

Spices have been used for health in many cultures for centuries. A traditional use tells you what people have done, not that it works. Here every spice is listed under the goals, body systems and actions its guide connects it to, and each link carries the strength of the evidence behind it.

Strongest

6 spices

Clinical trials support a benefit

Promising

47 spices

Early or mixed human evidence

Early science

16 spices

Lab or animal research only

Unknown

11 spices

Too little evidence to say

Each spice is counted once, at the strongest level its guide documents for any use. A strong label for one use says nothing about its other uses or its safety. "Traditional use" alone is not one of these labels: where a guide only reports history, the link is rated "Too little evidence to say". Read the guide on traditional use and research evidence.

Spices by wellness goal

Each card shows how many spices are linked to a goal and how strong the evidence is. Green means clinical trials support a benefit; grey means too little evidence. These are links the guides document, not recommendations. For the wider picture, see the Wellness Goals section.

Blood sugar, metabolism and weight

16spices

15 promising1 early science

Best-studied

See all 16 spices by strength of evidence

Early or mixed human evidence (15)

Lab or animal research only (1)

Goal pages: Blood Sugar Balance · Metabolic Health · Weight Management

Joints and mobility

1spices

1 promising

Best-studied

See all 1 spices by strength of evidence

Early or mixed human evidence (1)

Goal pages: Joint Support

Spices by body system, body part and action

The same links, organized the way anatomy and physiology textbooks do. "Action" describes what a spice is said to do (for example calming or digestive support); it names the claim, not the proof.

Body systems · 15 groups
Digestive System · 14 spices

Clinical trials support a benefit (1)

Early or mixed human evidence (12)

Lab or animal research only (1)

Blood Sugar Support · 12 spices

Early or mixed human evidence (11)

Lab or animal research only (1)

Heart & Circulation · 10 spices

Early or mixed human evidence (10)

Metabolism & Weight · 5 spices

Early or mixed human evidence (5)

Pain & Inflammation · 5 spices

Clinical trials support a benefit (3)

Early or mixed human evidence (2)

Cardiovascular System · 4 spices

Early or mixed human evidence (4)

Gut Health · 3 spices

Early or mixed human evidence (3)

Nervous System · 2 spices

Early or mixed human evidence (2)

Bones, Joints & Muscles · 1 spices

Early or mixed human evidence (1)

Musculoskeletal System · 1 spices

Early or mixed human evidence (1)

Brain & Focus · 1 spices

Early or mixed human evidence (1)

Reproductive Health · 1 spices

Early or mixed human evidence (1)

Stress & Mood · 1 spices

Early or mixed human evidence (1)

Kidney & Urinary · 1 spices

Early or mixed human evidence (1)

Urinary System · 1 spices

Early or mixed human evidence (1)

Body parts · 10 groups
Stomach · 6 spices

Clinical trials support a benefit (1)

Early or mixed human evidence (5)

Gut · 5 spices

Early or mixed human evidence (5)

Skin · 3 spices

Early or mixed human evidence (3)

Nervous System · 2 spices

Early or mixed human evidence (2)

Pancreas · 2 spices

Early or mixed human evidence (2)

Blood Vessels · 2 spices

Early or mixed human evidence (2)

Joints · 1 spices

Early or mixed human evidence (1)

Brain · 1 spices

Early or mixed human evidence (1)

Heart · 1 spices

Early or mixed human evidence (1)

Muscles · 1 spices

Clinical trials support a benefit (1)

Functional actions · 10 groups
Antioxidant · 15 spices

Lab or animal research only (15)

Digestive Support · 13 spices

Clinical trials support a benefit (1)

Early or mixed human evidence (11)

Lab or animal research only (1)

Blood Sugar Regulation · 10 spices

Early or mixed human evidence (8)

Lab or animal research only (2)

Anti-Inflammatory · 9 spices

Early or mixed human evidence (2)

Lab or animal research only (7)

Pain Relief · 6 spices

Clinical trials support a benefit (3)

Early or mixed human evidence (3)

Metabolic Optimization · 3 spices

Early or mixed human evidence (3)

Neuroprotective · 2 spices

Lab or animal research only (2)

Cardiovascular Support · 2 spices

Early or mixed human evidence (2)

Joint Support · 1 spices

Early or mixed human evidence (1)

Mood Support · 1 spices

Early or mixed human evidence (1)

Compare related spices

Side-by-side guides for spices that people confuse or choose between. They explain differences; they do not rank the spices.

What research shows, by health concern

Each guide below looks at one concern, from sleep to skin, and separates spices that were tested in people from spices that are only traditional or lab-tested.

Herbs by wellness goal: the full guide

Traditional uses of spices

People have used spices for health for many centuries. A traditional use tells you what people have done, not that it works. For what research found, see the Health Benefits and Scientific Evidence tabs.

Traditional spice medicine

Ayurveda, Traditional Chinese Medicine and other traditions each use natural remedies in their own systems. The spices below are the ones whose guide mentions the tradition in its own text. That a tradition uses a spice is history, not clinical evidence. Each guide says separately what trials found.

Ayurveda · 3 spices mention it
Unani and Siddha · 1 spices mention it
Europea spiceal tradition · 9 spices mention it
Latin American and Caribbean · 3 spices mention it

Read more: Therapies & Traditions.

Safety and side effects of spices

Spices are active substances. Some interact with prescription medicines, some are unsafe in pregnancy or with certain conditions, and some have been linked to serious harm. This tab brings together what the individual spice guides document, plus the general rules. Medicine interactions have their own tab.

If someone may have been poisoned or is seriously unwell

  • Collapse, seizure, trouble breathing, swelling of the face or throat, chest pain or a fast irregular heartbeat: call your local emergency number now (911 in the United States and Canada, 999 in the UK, 112 in the European Union).
  • Swallowed too much of a spice, or a child or pet got into a product, and the person seems well: in the United States call Poison Help, 1-800-222-1222 (free, 24 hours). Elsewhere, call your national poison centre or local emergency number.
  • Yellow skin or eyes, dark urine, severe belly pain, or a new rash after starting a spice: stop it and contact a clinician the same day.

Have the product bottle with you when you call. Poisoning: What to Do First · Poison Help by Country · Emergency Quick Reference: Whom to Call (911, 988, Poison Help)

Safety first with spices

  • A spice in normal cooking amounts is a food. Concentrated spice extracts and capsules are a different thing and can interact with medicines, for example blood thinners.
  • Some spices need extra care in pregnancy, with allergies (mustard, celery, sesame-family seeds) or with certain medicines. Each spice page lists what its sources say.
  • Tell your pharmacist or clinician about spice supplements, especially before surgery.
Read spice safety

General spice safety principles

  1. "Natural" does not mean safe. Natural products can contain strong substances; some are harmful. Natural Does Not Mean Safe
  2. Tell your pharmacist and clinician about every spice product you use, and ask before combining one with prescription or over-the-counter medicines.
  3. Be extra careful with narrow-margin medicines such as warfarin, antidepressants, immunosuppressants, diabetes and blood pressure medicines.
  4. Tell the surgical team about every spice before an operation. Many teams ask people to stop spice products ahead of surgery; ask yours how long.
  5. Pregnancy, breastfeeding, children and older adults are groups where good safety data are often missing, so official sources usually advise asking first.
  6. Start one product at a time, at the label amount, so a reaction can be traced. Stop and get advice if you feel unwell.
  7. Products vary. Contamination, substitution and mislabelling are documented problems; third-party testing can reduce but not remove the risk.
  8. Report a bad reaction to your national system (in the US, FDA MedWatch). Side Effects, Allergic Reactions & Reporting

Safety guides by topic

Natural Remedy Safety: the full department  · 

Documented risks and interactions, by concern

Each line comes from a spice's own guide, where it is backed by cited sources: 321 documented risks across 80 of the 80 spices. A spice missing from a list is not proven safe: it may simply not have been studied. Open the spice's guide for the full wording and sources.

Pregnancy and breastfeeding · 36 spices
Children and teenagers · 16 spices
Liver · 15 spices
SpiceWhat its guide documents
Bay leafLiver injury with daily tea (documented risk). A 2026 case report describes probable liver injury after regular bay leaf tea in one woman, who improved after stopping.
Black seed (nigella)Medicine interactions (liver enzymes, warfarin). MSK says it inhibits CYP2D6 and CYP3A4 and may raise levels of drugs cleared by them; thymoquinone weakened warfarin's action in …
Black seed (nigella)Liver and kidney effects at high doses (rats). High doses damaged rat liver and kidneys; MSK says human data are lacking.
CarawayLiver and bile-duct disease caution. The EU committee does not recommend caraway medicines in liver disease, cholangitis, gallstones or other bile-duct disorders.
CinnamonCoumarin in cassia and the liver. Cassia contains coumarin, linked to liver effects in some sensitive people. BfR sets a tolerable intake of 0.1 mg per kg of body …
Dried fenugreek leaf (kasuri methi)Liver toxicity reports. LactMed says liver toxicity has been reported, alone and in spice blends containing fenugreek. The 2023 pooling of trials saw no…
FenugreekLiver toxicity reports. LactMed says liver toxicity has been reported, alone and in spice blends containing fenugreek. The 2023 pooling of trials saw no…
Filé powder (ground sassafras leaf)Safrole and liver cancer in animals. Safrole, found mostly in sassafras root bark and oil, caused liver cancer in lab animals; MSK lists it as reasonably anticipated …
GalangalLiver enzymes and organ weights in an animal study. One animal study of galangal extracts reported higher liver enzymes and organ weights; a 90-day rat study of a standardized extra…
Grains of paradiseLiver weight increase in rats. In a 28-day rat study of a strong extract, liver weight and alkaline phosphatase rose with dose; authors said liver toxicity shou…
KokumLiver effects need more study. A review says no research directly links kokum to acute liver injury, but its liver effects deserve more study because it contain…
Mahlab (mahleb)Coumarin content of the kernel (liver limit). Kernels measured about 0.87 mg coumarin per gram and pitted berries about 0.63 mg per gram in one Italian study; white seeds had …
NutmegLiver and kidney changes at very high amounts (rats). Rats given nutmeg powder for 90 days at very high amounts had liver and spleen changes, and kidney damage at the higher amount.
Ras el hanoutLiver effects of some component products. NCCIH links highly absorbable curcumin supplements to liver harm and says cassia coumarin has been linked to liver effects. These…
Tonka beanCoumarin and the liver. Coumarin harmed the liver of dogs and rats at high doses, and a small share of people taking it as a drug had liver enzyme rises …
TurmericLiver injury with turmeric and curcumin supplements. Liver damage has been reported, especially with highly absorbable curcumin products. A US network described ten cases (2004 to 20…
Kidneys · 5 spices
SpiceWhat its guide documents
Black seed (nigella)Liver and kidney effects at high doses (rats). High doses damaged rat liver and kidneys; MSK says human data are lacking.
Juniper berryNot recommended in severe kidney disease or when fluids are limited. The EU says it is not recommended in severe kidney disease, including kidney infections, or for people told to limit fluids.
Lovage seedKidney inflammation and fluid medicines (documented risk). Root preparations are not advised in acute kidney inflammation or heart- or kidney-related swelling, and a consumer reference say…
NutmegLiver and kidney changes at very high amounts (rats). Rats given nutmeg powder for 90 days at very high amounts had liver and spleen changes, and kidney damage at the higher amount.
TurmericKidney stones and oxalate. MSK advises people prone to kidney stones to check with a doctor before turmeric supplements; one case of oxalate nephropathy wit…
Blood pressure and heart · 3 spices
SpiceWhat its guide documents
Dried citrus peelBitter orange supplements and the heart. NCCIH says bitter orange is likely safe in food amounts, but serious heart events have been reported with supplements, mostly mul…
GingerStomach upset, heartburn, allergy. NCCIH lists belly discomfort, heartburn, diarrhea and mouth irritation; EMA lists ginger allergy and skin reactions. Large food a…
Grains of paradiseHeart and organ marker changes in rats. A 30-day rat study of an extract reported changes in heart and liver markers and a heart-rhythm effect.
Hormone-sensitive conditions · 1 spices
SpiceWhat its guide documents
SaffronPregnancy: uterine stimulation and miscarriage risk. A 2026 review linked higher doses or occupational exposure to uterine stimulation and increased miscarriage risk.
Allergy and skin reactions · 57 spices
Common side effects · 19 spices
Toxicity, poisoning and legal restrictions · 17 spices
Product quality, contamination and substitution · 29 spices
Limited safety data · 2 spices
Other spice-specific cautions · 61 spices
SpiceWhat its guide documents
Ajwain (carom seed)Possible effect on blood clotting (reported, not verified). Wikipedia says an anti-clotting action may matter for people taking anti-inflammatory pain medicines or antiplatelet drugs. We co…
Aleppo pepperBurning and skin or eye injury. Capsaicin causes the burning feel; it irritates skin and eyes and washing does not remove it well. Very hot peppers can cause sto…
AllspiceMay slow blood clotting. A reference monograph says allspice might slow clotting, and may add to bleeding risk with blood thinners, antiplatelet drugs and…
AllspiceEugenol intake figure. WHO/JECFA gives an acceptable daily intake of 0 to 2.5 mg per kg body weight for eugenol, the main compound in allspice oil. This…
Amchur (dried green mango powder)Sulfites in some dried mango products. Ireland's food safety body warned in 2022 about a dried mango batch with sulphites missing from the label, which may be unsafe fo…
Anise (aniseed)Anethole genetic safety signal. Non-clinical studies showed a weak mutagenic potential of anethole, per the EU monograph as summarized in our spice guide.
Annatto (achiote)Heavy-metal limits in annatto extract. US rules limit arsenic to 3 ppm and lead to 10 ppm in annatto extract.
BaharatSalmonella in imported spices. FDA import testing found Salmonella in about 6.6 percent of spice shipments over three years, according to a news report on the 2…
Bay leafWhole leaf swallowed (documented risk). Whole bay leaves stay stiff when cooked and may harm the digestive tract or cause choking if swallowed.
Bay leafLook-alike plants (documented risk). California bay contains umbellulone, which can cause methemoglobinemia; other plants called bay or laurel are not true bay.
BerbereSalt in blends. Some berbere recipes add salt, and USDA's chili powder entry lists about 77 mg sodium per teaspoon. Amounts depend on the maker.
Black cardamomName confusion between plants. Two plants are called black cardamom (Amomum subulatum and Lanxangia tsaoko), and the green kind is a third plant; labels and ref…
Black cardamomGallstones (cardamom in general). A consumer reference advises people with gallstones to keep to food amounts of cardamom because the seed can trigger gallstone co…
Black cardamomDoses and risks of concentrated forms not studied. A review says optimal doses, forms and possible health risks of cardamom compounds still need thorough investigation.
Cajun and Creole seasoningSodium from salted blends. Many Cajun and Creole blends contain salt. WHO advises adults to keep sodium under 2,000 mg (under 5 g salt) a day and to flavor …
Cajun and Creole seasoningSalmonella in dried spices. FDA found less Salmonella in retail spices than in imports for 9 of 11 spice types (dehydrated garlic and basil were exceptions) …
CardamomGallstone colic. A consumer reference advises people with gallstones to keep to food amounts, because the seed can trigger gallstone colic.
Cayenne and chili pepperBurning and skin or eye injury. Capsaicin burns eyes, broken skin and mucous membranes; skin products must not be used on broken skin, wounds, eczema, or near th…
Celery seedSeed oil irritation and sensitization (documented risk). An EFSA panel concluded celery seed oil should be treated as an irritant to skin and eyes and as a skin and respiratory sensitize…
Chaat masalaSodium from salt. Chaat masala contains salt, often black salt, so it adds sodium to food.
Chaat masalaGerms in imported spices. Salmonella was found in about 6.6% of imported spice shipments in 2007 to 2009; retail rates were lower.
Chili powderSodium in salted blends. USDA's chili powder entry has about 77 mg sodium per teaspoon and about 230 mg per tablespoon (about 10% of the 2,300 mg daily va…
Chili powderSynthetic dyes added to some chili products. Wikipedia reports that unscrupulous traders have added harmful synthetic dyes (such as Sudan dyes and Rhodamine B) to chili produ…
Chili powderSalmonella in dried spices. FDA found lower Salmonella prevalence in retail packaged spices than in imports for 9 of 11 spice types and says makers often tre…
Chinese five-spiceCoumarin from cassia cinnamon. Cassia cinnamon contains coumarin. BfR sets a tolerable intake of 0.1 mg per kg body weight per day, reached by about 2 g of aver…
Chipotle (smoked jalapeno)Burning and skin or eye irritation. MSK reports contact dermatitis in a woman after preparing a meal with red chilies, and eye or nose irritation as a patient-report…
CinnamonSkin irritation. Cinnamon oil or powder on the skin may cause irritation or contact dermatitis.
CinnamonSpecies mix-up on labels. Products often do not say which species or plant part was used, and some Ceylon is mixed with cassia.
ClovesClove cigarettes and lung injury. Clove cigarettes are tobacco products; their smoke was linked to severe lung injury in a few susceptible people.
Cubeb pepperCubebin may irritate mucous membranes. Wikipedia states that cubebin, a compound in the fruit, irritates mucous membranes.
Curry leafPesticide residues on fresh leaves. An Indian monitoring study found curry leaf among the commodities with the highest residues; chlorpyrifos, profenophos and ethion…
Curry powderSalmonella in dried spices. FDA found lower Salmonella prevalence in retail packaged spices than in imports for 9 of 11 spice types, and says makers often tr…
Dill seedSafe as a food (US FDA GRAS). LactMed reports dill is generally recognized as safe as a food by the US FDA and generally well tolerated; nursing mothers given …
Dried black lime (loomi)Grapefruit-type warning for citrus. FDA says grapefruit and some related citrus can change how certain medicines work; limes are not named.
Dried citrus peelMold and aflatoxin in stored peel. A review of chenpi says moisture and polysaccharides allow mold in storage and that Aspergillus can make aflatoxins.
Dried citrus peelSkin irritation from limonene. Limonene, the main compound in orange peel oil, can irritate skin.
Dried fenugreek leaf (kasuri methi)Maple-syrup body odor. LactMed says fenugreek can give urine, sweat, feces and possibly breast milk a maple-syrup smell, caused by sotolon.
DukkahSesame must be declared; recipes may have changed. Since January 1, 2023 sesame must be declared on packaged US foods, and FDA warns that some recipes now include small amounts of …
DukkahSalmonella in dried spices. FDA found Salmonella less often in retail dried spices than in imported shipments and linked this to treatment after import. No d…
Fennel seedDuration limit. EMA says adults should not take fennel tea for more than 2 weeks, and children aged 4 to 12 less than one week.
FenugreekMaple-syrup body odor. LactMed says fenugreek can give urine, sweat, feces and possibly breast milk a maple-syrup smell, caused by sotolon.
Filé powder (ground sassafras leaf)US food rule on added safrole and oil of sassafras. Food with added safrole or oil of sassafras is treated as adulterated, including sassafras tea.
Filé powder (ground sassafras leaf)Higher safrole in root bark tea and tinctures. Brewed root bark teas held 0.09 to 4.66 mg of safrole per cup in the 1997 FDA test; one oil reached 92.4%.
Garam masalaCassia coumarin limit. If the blend uses cassia, coumarin adds to the daily total; BfR sets 0.1 mg per kg body weight per day.
Garam masalaNutmeg in large amounts. Poison-centre cases of nutmeg ingestion were mostly deliberate or accidental large amounts, including young children.
Garlic powderSkin burns from raw garlic. Fresh raw garlic on the skin can cause severe irritation and chemical burns.
Garlic powderSalmonella in imported spices. FDA's 2013 draft found spice shipments had about twice the Salmonella contamination of other imported foods. It covers spices in …
GingerGallstones. Memorial Sloan Kettering advises people with gallstones to avoid supplements because ginger may increase bile flow.
Grains of SelimLow platelets in long rat study. In a 90-day rat study of the dried fruit, platelet counts fell at 75, 150 and 300 mg per kg a day.
Grains of SelimReproductive effects of xylopic acid in mice. A review says harmful effects of xylopic acid on the reproductive system of mice are well documented.
Herbes de ProvenceSalmonella and filth in imported spices. FDA's spice risk profile found Salmonella in imported spice shipments; a 2018 update found significantly lower rates in retail pa…
Horseradish and wasabiIrritation of nose, eyes and sinuses. The heat compound irritates the mucous membranes of the sinuses and eyes.
Horseradish and wasabiThyroid: iodine uptake and cruciferous thiocyanates. The review says thiocyanates from cruciferous vegetables can reduce iodine uptake; it gives no data specific to horseradish or wa…
Indian bay leaf (tej patta)Coumarin and other cinnamon-genus cautions (not measured for this leaf). A review says coumarin in some cinnamon species may harm the liver and lists possible drug interactions for cinnamon in general; …
Indian bay leaf (tej patta)Mix-ups with other bay leaves. Tej patta is often sold as plain bay leaf, so the plant bought may not be the one intended.
Jamaican jerk seasoningChili heat and skin or eye irritation. Capsaicin from hot chilies such as scotch bonnet irritates skin and eyes on contact; plain water is generally ineffective at remo…
Jamaican jerk seasoningSalt in dry jerk blends. One maker's dry blend lists 176 mg of sodium per teaspoon, and recipes often add salt or soy sauce. USDA SR Legacy has no jerk en…
Kashmiri chiliPossible link with gastrointestinal cancers. A 2022 pooling of 14 case-control studies linked high chili intake with higher risk of GI cancers (OR 1.64, 1.00 to 2.70), mainly…
KokumGarcinia cambogia product safety (related species). NCCIH says Garcinia cambogia products may be unsafe, with reports of liver damage, and may interact with drugs that affect the li…
Long pepperMonitoring with phenytoin. A 2025 review suggests monitoring when piperine is taken with the seizure medicine phenytoin, because blood levels may rise.
Long pepperReproductive and embryo effects of isolated piperine (animals). BfR reviewers noted that animal studies with high daily doses of isolated piperine showed disturbed sperm production and harm to …
MaceSafrole content of the oil. EFSA classes nutmeg oil as a category 1B carcinogen because of its safrole, which caused cancer in rodents.
Mahlab (mahleb)Cyanide-forming compounds in cherry-family seeds. One 2023 analysis found an amygdalin compound only in red and roasted red seeds; a spice reference says earlier literature did no…
Mastic (mastiha)Use under 18. The EU monograph does not recommend oral use under 18 (and skin use under 12) because of a lack of data.
Mastic (mastiha)Product authenticity. Mastic is one of the most expensive food items after saffron, so quality and labelling can matter; we could not verify adulterati…
Mustard seedSkin burns from mustard plasters. Case reports describe second-degree burns when mustard powder was applied to skin as a plaster; lesions appear within hours.
Mustard seedCross-reactivity with other Brassicaceae seeds. Health Canada says mustard proteins resemble those in other cabbage-family seeds; allergic people should avoid their seeds and sp…
Onion powderFructan content and IBS symptoms. A 2024 study found onion had the highest fructan of 40 foods (1.97 g per 100 g fresh weight); fructans ferment quickly and can wo…
Panch phoronSalmonella in imported spices. FDA import testing found Salmonella in about 6.6 percent of spice shipments, per a news report on the 2013 draft risk profile.
PaprikaPossible added dye or removed oleoresin (authenticity). A Slovenian study of 45 paprika samples saw signs consistent with possible added dye or removed oleoresin in some, and said this …
Pink peppercornRegulatory status in the US. Neither Schinus species has FDA generally-recognized-as-safe status according to Wikipedia; FDA banned imports of Brazilian peppe…
Poppy seedPoppy seed tea hazard. Home-brewed tea from online-bought seeds could yield potentially lethal amounts of morphine; seed levels ranged from under 1 to 2…
Poppy seedOpium alkaloid exposure from food. EFSA set an acute reference dose of 10 micrograms of morphine per kg of body weight in 2011 and said big eaters of seeds are like…
Pumpkin pie spiceCassia coumarin limit. If the blend uses cassia, coumarin adds to the daily total; BfR sets 0.1 mg per kg body weight per day and says about 2 g of aver…
Pumpkin pie spiceNutmeg in large amounts. Poison-centre cases of nutmeg were mostly accidental ingestion by young children or deliberate large amounts.
Ras el hanoutSalmonella in dried spices. FDA found Salmonella less often in retail spices than in imported shipments and linked this to treatment after import.
Ras el hanoutOld formulas with cantharides. Some older Moroccan formulas included cantharides, a notoriously dangerous beetle; the source says they are irrelevant to flavori…
SaffronMood changes and mania. Reported side effects included nervousness, irritability, hypomania and restlessness; people with psychiatric conditions are flag…
Sesame seedCross-reaction with peanut and tree nuts. Wikipedia says sesame cross-reacts with peanuts, hazelnuts and almonds, and that allergy is far more common in Middle Eastern cou…
Sesame seedRancidity of the oil-rich seed. The seeds are very oil-rich and can go rancid; an extension service advises airtight, cold or cool dark storage and checking by s…
Shichimi togarashiPoppy seed opium alkaloids. EFSA keeps a safe level of 10 micrograms per kg body weight for morphine and codeine combined and says large amounts of unprocess…
Shichimi togarashiSalmonella in imported spices. FDA import testing found Salmonella in about 6.6 percent of spice shipments in fiscal years 2007 to 2009, according to a news rep…
Smoked paprika (pimentón)Smoke leaves PAH residues in the powder. Drying peppers over wood smoke adds PAHs, including benzo[a]pyrene. Measured levels range from about 6 to 97 micrograms per kg in…
Smoked paprika (pimentón)Modelled PAH risk from smoked spices. A 2025 risk model found most commercial spice samples acceptable but said smoked paprika and black pepper need monitoring, and th…
Smoked paprika (pimentón)Mold and mycotoxins during drying and storage. In six La Vera dryers, mold was found but mycotoxins were not detected in the dried peppers. In the lab, damp storage let aflatox…
Smoked paprika (pimentón)Authenticity of Pimenton de la Vera. Lab methods exist to detect smoked paprika mixed with pepper varieties from outside the La Vera region.
Tonka beanUS ban on tonka bean in food. In the US, food containing added coumarin or tonka beans or extract is legally adulterated (21 CFR 189.130).
Tonka beanTolerable daily intake of coumarin. EFSA set 0.1 mg per kg body weight per day and BfR confirmed it in 2012; children reach it more easily than adults.
Tonka beanFake vanilla containing tonka bean. FDA warned that some cheap Mexican vanilla contained coumarin from tonka bean and advised buying only products labelled vanilla b…
VanillaFake vanilla containing coumarin. Some cheap Mexican 'vanilla' has been found to contain coumarin from tonka bean. Coumarin is related to warfarin, so the FDA warn…
VanillaAlcohol in vanilla extract. Pure vanilla extract in the US must contain at least 35% alcohol, which matters for people who avoid alcohol.
White pepperReproductive effects in animals (high-dose piperine). In animals, higher daily piperine doses than human interaction studies caused signs of disturbed sperm formation and maternal and…
Za'atarSalt (sodium) content. Za'atar contains salt, and the amount varies by mix. WHO says too much sodium mainly raises blood pressure.
Za'atarFillers such as wheat flour in commercial blends. Some commercial versions add wheat flour as a filler.
Za'atarSalmonella in spices. FDA found Salmonella less common in retail packaged spices than in imported shipments for 9 of 11 spice types studied. Sesame and…

Spice and medicine interactions

Some spices change how a medicine works, or add to its effect. This matters most for narrow-margin medicines such as blood thinners, antidepressants, immunosuppressants, and diabetes and blood pressure medicines. Always tell your pharmacist and clinician about every spice you take. Ask before starting, stopping or combining anything.

Interaction and surgery guides

 ·  Medication interactions in Natural Remedy Safety

Documented interactions, by concern

Each line comes from a spice's own guide and its cited sources. A spice missing from a list is not proven free of interactions: it may simply not have been studied. Open the spice's guide for the full wording.

Medicine interactions (prescription and over the counter) · 34 spices
SpiceWhat its guide documents
Aleppo pepperMedicine interactions (supplement level). MSK says capsaicin may change blood pressure medicines, may add to ACE-inhibitor cough, and should be avoided with cyclosporin af…
Ancho chilePossible medicine interactions (capsicum supplements). MSK lists possible interactions with cyclosporine, ACE inhibitors, antiplatelet drugs and some drugs handled by liver enzymes, mo…
BaharatBlack pepper (piperine) and medicines. Piperine can change how the body handles some medicines, with helpful or harmful effects depending on dose, schedule and duration.
BerbereChili irritation and medicine interactions. MSK lists sweating, eye, nose and stomach irritation as common effects, and says cayenne supplements may affect blood pressure me…
Black pepperMedicine interactions with isolated piperine. German risk assessors found that isolated piperine taken in one dose interacted with several medicines, in most cases raising dru…
Black seed (nigella)Medicine interactions (liver enzymes, warfarin). MSK says it inhibits CYP2D6 and CYP3A4 and may raise levels of drugs cleared by them; thymoquinone weakened warfarin's action in …
CardamomPossible medicine interactions (diabetes drugs). The umbrella review urges monitoring for low blood sugar when spice medicines are used with diabetes drugs, noting a lack of her…
Cayenne and chili pepperMedicine interactions (supplement level). MSK says capsaicin may affect blood pressure medicines, increase ACE-inhibitor cough, and should be avoided with cyclosporin; ani…
Chipotle (smoked jalapeno)Medicine interactions (supplement level). MSK says capsaicin may affect blood pressure medicines, raise ACE-inhibitor cough and should be avoided with cyclosporine; other …
CinnamonPossible medicine interactions. NCCIH says some components might, in theory, interact with an anticancer drug or with nicotine.
ClovesPossible bleeding effect with blood thinners. Clove oil reduced platelet clumping in laboratory tests; the EU assessor called a blood-thinner interaction theoretical for short…
Cubeb pepperPossible change in how medicines are processed (lab only). In test-tube assays, several compounds from cubeb blocked CYP3A4, a liver enzyme that processes many medicines, about as strongly…
Dried black lime (loomi)Lime juice and medicine-processing enzymes. Lime juice had more bergamottin than grapefruit juice and blocked CYP3A4 in the lab; in a crossover trial quarter-strength lime j…
Dried citrus peelMedicine interaction with Seville orange peel. A trial found Seville orange juice raised felodipine levels by 76% versus common orange juice; FDA says Seville oranges might act…
Dried fenugreek leaf (kasuri methi)Low blood sugar with diabetes medicines. Large doses may cause a harmful drop in blood sugar (NCCIH). EMA says blood glucose should be monitored closely in people with di…
Dried fenugreek leaf (kasuri methi)Warfarin and bleeding. LactMed says fenugreek can interact with warfarin to cause bleeding and advises caution with high amounts.
FenugreekLow blood sugar with diabetes medicines. Large doses may cause a harmful drop in blood sugar (NCCIH). EMA says blood glucose should be monitored closely in people with di…
FenugreekWarfarin and bleeding. LactMed says fenugreek can interact with warfarin to cause bleeding and advises caution with high amounts.
Garam masalaPiperine and medicines. Isolated piperine as a bolus raised levels of some drugs in studies; animal studies at higher doses showed reproductive effects.
GingerBleeding risk with blood thinners and NSAIDs. Memorial Sloan Kettering advises against ginger supplements with warfarin, other blood thinners, NSAIDs or bleeding disorders; di…
GingerOther medicine interactions. Memorial Sloan Kettering notes possible larger blood sugar drops with diabetes medicines, higher tacrolimus and lower cyclosporin…
Grains of SelimInteraction with antidepressants in mice. In mice, the extract and xylopic acid acted together with three antidepressants and lowered the blood level of imipramine.
Herbes de ProvenceThyme medicines in pregnancy and under 12. EMA says most thyme preparations should only be used by adults and adolescents over 12. Its summary page does not mention pregnan…
Kashmiri chiliMedicine interactions (capsaicin). MSK lists possible effects on blood pressure drugs, ACE inhibitor cough, theophylline absorption and cyclosporine levels; some cl…
Long pepperPossible change in how medicines are absorbed. Piperine, the pungent compound in long pepper and black pepper, blocks a medicine transporter and a liver enzyme in lab tests; re…
Long pepperProbable warfarin interaction (case report). A 2026 case report judged an interaction between warfarin and a toothache solution containing long pepper as probable, with unsta…
Lovage seedKidney inflammation and fluid medicines (documented risk). Root preparations are not advised in acute kidney inflammation or heart- or kidney-related swelling, and a consumer reference say…
MacePossible effect on mood medicines (monoamine oxidase). Myristicin moderately inhibits monoamine oxidase, an enzyme that some mood medicines also act on.
NutmegPossible link to mood medicines. A case report notes myristicin moderately inhibits monoamine oxidase; a man on fluoxetine and quetiapine had a mild course after …
Poppy seedOpiate urine drug test positives. In 12 volunteers, urine morphine reached 155 to 1,408 ng/mL after a poppy seed roll and 294 to 4,213 ng/mL after raw seeds. In a …
Safflower ("false saffron")Bleeding risk and blood-thinner medicines. A consumer drug reference lists blood thinners and antiplatelet drugs as medicines to discuss before using safflower flower; inte…
SaffronBleeding with blood thinners. One case report described acute bleeding in a man taking rivaroxaban with a saffron supplement.
Shichimi togarashiChili: irritation and medicine effects. Memorial Sloan Kettering lists stomach, eye and nose irritation for chili, case reports of rash in nursing infants and of anaphyl…
Star aniseAllergy: anaphylaxis after flu medicine in a sensitized patient. A case report links sensitization to star anise, with celery-carrot-mugwort-spice syndrome, to anaphylaxis after oseltamivir.
TamarindRaised aspirin absorption. In six healthy adults in 1991, 600 mg of aspirin taken with a water extract of tamarind was absorbed more than aspirin alone.
Tonka beanBlood thinners and coumarin in fake vanilla. FDA warned in 2008 that coumarin is related to warfarin and may raise bleeding risk; a 2022 review says coumarin itself has no an…
TurmericBleeding and medicine interactions. MSK says turmeric may raise bleeding risk with warfarin and other blood thinners (lab data and one case report), and may weaken a…
White pepperMedicine interactions with piperine. Piperine may raise blood levels of several drugs and so their effects; the effect can help or harm depending on dose and timing.
Bleeding, surgery and anesthesia · 11 spices
SpiceWhat its guide documents
AllspiceSurgery: bleeding concern. The same monograph advises stopping allspice at least 2 weeks before planned surgery.
ClovesPossible bleeding effect with blood thinners. Clove oil reduced platelet clumping in laboratory tests; the EU assessor called a blood-thinner interaction theoretical for short…
Dried fenugreek leaf (kasuri methi)Warfarin and bleeding. LactMed says fenugreek can interact with warfarin to cause bleeding and advises caution with high amounts.
FenugreekWarfarin and bleeding. LactMed says fenugreek can interact with warfarin to cause bleeding and advises caution with high amounts.
Garlic powderBleeding risk and surgery. Garlic supplements may increase the risk of bleeding, so tell your providers, especially before surgery or if you take anticoagul…
GingerBleeding risk with blood thinners and NSAIDs. Memorial Sloan Kettering advises against ginger supplements with warfarin, other blood thinners, NSAIDs or bleeding disorders; di…
GingerSurgery. Memorial Sloan Kettering advises stopping ginger supplements 2 weeks before surgery.
Herbes de ProvenceOregano tea and a blood-thinner test. A 2025 case report describes a 77-year-old woman on acenocoumarol whose clotting test (INR) rose to 6.42 after about a week of on…
Safflower ("false saffron")Bleeding risk and blood-thinner medicines. A consumer drug reference lists blood thinners and antiplatelet drugs as medicines to discuss before using safflower flower; inte…
SaffronBleeding with blood thinners. One case report described acute bleeding in a man taking rivaroxaban with a saffron supplement.
Tonka beanBlood thinners and coumarin in fake vanilla. FDA warned in 2008 that coumarin is related to warfarin and may raise bleeding risk; a 2022 review says coumarin itself has no an…
TurmericBleeding and medicine interactions. MSK says turmeric may raise bleeding risk with warfarin and other blood thinners (lab data and one case report), and may weaken a…
Blood sugar and diabetes medicines · 3 spices
SpiceWhat its guide documents
CardamomPossible medicine interactions (diabetes drugs). The umbrella review urges monitoring for low blood sugar when spice medicines are used with diabetes drugs, noting a lack of her…
Dried fenugreek leaf (kasuri methi)Low blood sugar with diabetes medicines. Large doses may cause a harmful drop in blood sugar (NCCIH). EMA says blood glucose should be monitored closely in people with di…
FenugreekLow blood sugar with diabetes medicines. Large doses may cause a harmful drop in blood sugar (NCCIH). EMA says blood glucose should be monitored closely in people with di…

Scientific evidence and research on spices

For most spices, good human evidence is limited. Every outcome in our spice guides is rated for how strong the evidence is, and the rating is shown next to it. Across the 80 guides, 74 spices have no outcome rated "clinical trials support a benefit".

What the evidence ratings add up to

  • 6Clinical trials support a benefitTrials in people support a defined effect, usually a narrow one.
  • 124Early or mixed human evidenceSmall, short or disagreeing studies. Positive and negative findings both count here.
  • 83Lab or animal research onlySeen in cells or animals. This does not show a benefit in people.
  • 95Too little evidence to sayPopular claims for which we found no usable human trials.
  • 321Documented risksSafety findings, shown in the Safety tab.

How to read spice research

  • Lab, animal and human studies answer different questions. A chemical that kills cells in a dish, or helps mice, may do nothing in people.
  • A mechanism is not proof of benefit. Knowing which compounds a spice contains, or which pathway they touch, explains how an effect might happen, not that it does.
  • A study that mentions a spice does not show the spice works. Many records only name the spice, test it in animals, or find no effect.
  • Product and form matter. A result for one extract, dose or tea does not carry over to another product.
  • Look at size, length and who paid. Small, short or industry-funded trials are more likely to overstate effects; a single trial is rarely enough.

Outcomes with the strongest human evidence (6)

These are the outcomes our guides rate "clinical trials support a benefit", each with the sources the guide cites. Even here, the effect is usually for one preparation, one group of people and one outcome.

SpiceOutcomeWhat the guide saysSources
Ancho chileMuscle pain (skin plaster or gel)The EU spice monograph accepts capsicum plasters and gels for relief of muscle pain such as low back pain. EMA/HMPC: EU herbal monograph on Capsicum annuum var. minimum / small-fruited C. frutescens, fructus (2015)
Annatto (achiote)Safety of annatto food color (daily limits set)EFSA set daily intake limits for the annatto pigments bixin and norbixin and found no genotoxicity concern for annatto E. EFSA: Exposure assessment of annatto colouring principles bixin and norbixin (E 160b) (2017)EFSA: Safety of annatto E and exposure to bixin and norbixin (E 160b) (2019)
CarawayIndigestion symptoms (with peppermint oil)A 2023 Cochrane review said fixed peppermint-plus-caraway oil capsules probably give a large improvement in overall indigestion symptoms at four weeks, with little or no difference in side effects. Cochrane Database of Systematic Reviews (Europe PMC abstract): Non-Chinese herbal medicines for functional dyspepsia (2023)Evidence-Based Complementary and Alternative Medicine (Europe PMC abstract): Peppermint Oil and Caraway Oil for Functional Dyspepsia: systematic review and meta-analysis (2019)
Cayenne and chili pepperPain relief on the skin (muscle pain)The EU regulator accepts defined capsaicin plasters and creams as well-established use for relief of muscle pain such as low back pain. EMA/HMPC (EU): Herbal monograph on Capsicum annuum var. minimum and small-fruited C. frutescens, fructus (2015)
GingerMotion-sickness nauseaEMA accepts powdered ginger for preventing motion-sickness nausea in adults; NCCIH says most studies have not shown benefit. European Medicines Agency: Zingiberis rhizoma - herbal medicinal product (2026)NCCIH (NIH): Ginger: Usefulness and Safety (2025)
Kashmiri chiliNerve pain from the skin (prescription 8% capsaicin patch)Cochrane found about 10% more people improved with the 8% patch than with a low-dose control in postherpetic neuralgia, with evidence of moderate to very low quality. Cochrane (via Europe PMC): Topical capsaicin (high concentration) for chronic neuropathic pain in adults (2017)

Evidence by spice and outcome

How many outcomes each guide rates in each evidence group. Open a guide for the individual outcomes, what was found (including negative results) and the sources.

Show the evidence table for all 80 spices
SpiceTrials supportEarly / mixedLab / animalNot enoughRisks
Ajwain (carom seed)03113
Aleppo pepper03015
Allspice00415
Amchur (dried green mango powder)01114
Ancho chile14004
Anise (aniseed)03024
Annatto (achiote)12103
Asafoetida (hing)02013
Baharat00014
Bay leaf02103
Berbere02005
Black cardamom00324
Black pepper02114
Black seed (nigella)03234
Cajun and Creole seasoning00014
Caraway10133
Cardamom04124
Cayenne and chili pepper14124
Celery seed03203
Chaat masala00014
Chili powder00016
Chinese five-spice00114
Chipotle (smoked jalapeno)04114
Cinnamon03027
Cloves02215
Coriander seed03124
Cubeb pepper00332
Cumin03014
Curry leaf01212
Curry powder00013
Dill seed03023
Dried black lime (loomi)00212
Dried citrus peel01115
Dried fenugreek leaf (kasuri methi)04017
Dukkah01013
Fennel seed02025
Fenugreek04017
Filé powder (ground sassafras leaf)00133
Galangal04412
Garam masala00015
Garlic powder03026
Ginger14016
Grains of paradise02104
Grains of Selim00303
Herbes de Provence00014
Horseradish and wasabi03115
Indian bay leaf (tej patta)00403
Jamaican jerk seasoning00014
Juniper berry02125
Kashmiri chili13014
Kokum01302
Long pepper00414
Lovage seed01304
Mace01114
Mahlab (mahleb)00122
Makrut (kaffir) lime leaf00312
Mastic (mastiha)03014
Mustard seed02123
Nutmeg01115
Onion powder02023
Panch phoron01014
Paprika02214
Pink peppercorn00314
Poppy seed01015
Pumpkin pie spice00014
Ras el hanout00015
Safflower ("false saffron")00314
Saffron03015
Sesame seed04014
Shichimi togarashi01015
Sichuan (Szechuan) pepper00313
Smoked paprika (pimentón)01105
Star anise01124
Sumac03132
Tamarind01033
Tonka bean00015
Turmeric04016
Vanilla00313
White pepper01113
Za'atar00116

Where the evidence comes from

The guides cite 430 distinct sources. These are the ones cited most often, and the main places to check any spice claim yourself.

Limits of the research and gaps

  • Many spice trials are small, short, and test a specific extract that is not what most people buy.
  • Natural products vary with source, growing or mining conditions and processing, so two products with the same name can differ in what they contain.
  • Safety is studied less than benefit: long-term use, children, pregnancy and combinations with medicines are often unstudied.
  • Positive trials are published more often than negative ones, and many reviews pool trials of very different quality.

Spice forms, preparations and quality

The same material can be sold as a powder, capsule, liquid or concentrated extract, and these are not interchangeable. A study of one preparation does not tell you what another does. This tab shows which forms each guide describes, and how to judge product quality.

Parts used

Different parts can contain different compounds, so the part named on the label matters.

Teas, tinctures, capsules, powders and topical products

For each kind of preparation, the spices whose guides describe it. The guides say which form was actually studied. Detailed preparation instructions are in Herbal Teas & Extracts, so they are not repeated here.

Teas, infusions and decoctions · 24 guides describe it

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Tinctures and liquid extracts · 6 guides describe it

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Capsules and tablets · 31 guides describe it

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Powders and ground spice · 68 guides describe it

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Standardized and concentrated extracts · 49 guides describe it

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Creams, oils, salves and other topical forms · 47 guides describe it

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Whole, fresh or dried spice · 75 guides describe it

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Whole spice, standardized extract, and what the numbers mean

A whole spice (fresh, dried or powdered) contains everything in the raw material, in amounts that vary. A standardized extract is made to contain a stated amount of one or more marker compounds, which makes batches more consistent but is not the same as the whole spice.

An extraction ratio such as 4:1 says how much raw material was used per unit of extract. It does not by itself say how much active compound a capsule holds or whether the product works. A marker compound is something measured for quality control; it is not always the compound that causes any effect.

Amounts and duration. We do not give universal dose recommendations. Where a source reports the amount and length of use tested for a named preparation, the spice's guide gives it in that context; an amount studied in one product does not carry over to another, or to food-level use.

Absorption. Some active constituents are poorly absorbed, which is why concentrated or specially formulated products exist (curcumin is the best-known case). Better absorption can also raise the risk of side effects.

Comparison guides

Identification, labels and product quality

A good label names the species by its scientific name, says which part is used, and states the amount and form. Third-party testing can check identity, strength and contamination, but a seal is not a guarantee of safety or benefit.

Forms & preparations: the full guide  ·  Herbal Teas & Extracts

Complete See every spice by flavor

Content last updated . The tabs from Health Benefits onward are compiled automatically from the evidence ratings and sources in each spice's guide (last data update November 14, 2026). This section has not been medically reviewed.

Education, not medical advice. This section is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe.