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Nutmeg: Flavor, Cooking Use and Health Facts

Nutmeg is warm, slightly sweet and used in baking, sauces and drinks; large amounts can poison people, and no trial supports a health benefit when eaten.

Content last updated . This page has not been medically reviewed.

Close-up of nutmeg: flavor, cooking use and health facts

In the kitchen at a glance

Flavor:Warm / woodySweetEarthy

Aroma: Warm, sweet and woody, with a pungent edge.

Used in: baking, desserts, soups and stews, tea and drinks, vegetables

Usual amount in food: About 1/4 teaspoon (0.5 g) is a common grated pinch; USDA lists 2.2 g per teaspoon of ground nutmeg, and we found no official recipe amount.

What it is

Nutmeg is the seed of the tree Myristica fragrans. Mace, a second spice, is the red, lacy covering around the same seed. [1] The tree is native to the Banda Islands of Indonesia, and is also grown in Grenada, Malaysia and southern India. [1] A dried nutmeg is about 5 to 10 g. [1]

Flavor and aroma

Nutmeg smells pungent and tastes warm and slightly sweet. [1] Mace is more delicate than nutmeg and gives light dishes a bright orange color. [1] The scent comes from the seed's oil, which holds many compounds, including myristicin, safrole and pinene. [1] The same oil compounds are the ones linked to poisoning when too much is eaten. [5]

How it is used in cooking

Whole nutmegs are grated fresh with a small grater. Ground nutmeg is sold in jars. [1] The sources we read do not give rules for when to add it, so we give none.
  • Baking and sweets: puddings, cakes, pumpkin pie and eggnog. [1]
  • Vegetables and potatoes: potato and spinach dishes, and Dutch dishes of Brussels sprouts, cauliflower and green beans. [1]
  • Meat and filling: sausages, meatloaf, haggis and tortellini filling. [1]
  • Soups and stews: Indonesian soups such as soto and bakso, and the stew semur. [1]
  • India: sweet and savory dishes, and a small amount in garam masala. [1]
  • Drinks: mulled wine and cider, and Caribbean rum punches. [1]

We did not find a source we trust for substitutes or substitution ratios, so we do not give them.

Normal food amounts

MeasureGramsSource
1 teaspoon, ground nutmeg2.2 gUSDA [10]
1 tablespoon, ground nutmeg7.0 gUSDA [10]
1 teaspoon, ground mace1.7 gUSDA [10]
Typical recipe amountNot foundWe opened no source that states one

What one teaspoon (2.2 g) of ground nutmeg provides, calculated from USDA values per 100 g:

NutrientOne teaspoon
Energyabout 12 kcal
Fatabout 0.8 g
Fiberabout 0.5 g
Calciumabout 4 mg
Magnesiumabout 4 mg
Manganeseabout 0.06 mg

The USDA SR Legacy data are from 2018, and real products vary. [10] We did not compare these numbers with official daily values, so we do not call nutmeg a "good source" of anything. A pinch is mostly flavor.

Buying, storing and preparing

  • Forms: whole nutmeg (the seed), ground nutmeg, mace blades and ground mace. The essential oil is used in some foods and in cough syrups and toothpaste. [1]
  • Whole or ground: whole nutmeg can be grated as needed. [1]
  • Storing and shelf life: the sources we read give no shelf life or storage advice. Keeping spices cool, dry and sealed is common sense, not a sourced rule.
  • Quality and adulteration: the sources we read do not describe any quality problem for nutmeg.
  • Keep it away from children: children made up a large share of accidental exposures in a US poison-center series. [2]

Health: what research says

Eating nutmeg in cooking is very different from swallowing it by the spoonful or taking it as a remedy.

Food amounts vs supplements

In normal cookingIn supplements and extracts
Typical amountAbout 2.2 g per teaspoon (USDA); no recipe amount found [10]No official amount found
What studies mostly usedAlmost none; research is mostly poison reports and animal workLab and animal studies; one human trial of a skin product [7][9]
What we can say about benefitCulinary amounts produce no noticeable effects, per one reference [1]No human trial we read shows a benefit when taken by mouth [9]
Main safety limitVery large amounts can cause delirium, fast heartbeat and sleepiness [4][6]Poisoning reports; liver and kidney changes in rats at very high amounts [8]

What the evidence shows

UseWhat the sources foundStrength of evidenceForm and population
Painful diabetic nerve symptomsIn a 74-person trial, a skin product with nutmeg and mace oils did not add benefit over the comparison product after 4 weeks. [7]No good evidence of benefitSkin product; adults with diabetes in Trinidad [7]
Blood sugar, inflammation, cancer, memoryA 2025 review describes antioxidant, antidiabetic and anticancer effects in cells and animals. It says more clinical research is needed. [9]Lab or animal onlyExtracts and isolated compounds [9]
Digestive upset or diarrhea (traditional)Not supported by any trial we read.Insufficient evidenceTraditional use only
Poisoning from large amountsPoison-center series and case reports describe harm; most are mild, a few are severe. [2][3][4][5][6]Documented harmTeens, adults and young children
Long-term high intakeRats given nutmeg powder for 90 days at very high amounts had liver and spleen changes, and kidney damage at the higher amount. [8]Lab or animal onlyRats; not cooking amounts [8]

For more on the poison reports and remedy use, see the full herb guide: Nutmeg.

Official statements

  • Poison centers (US and Switzerland): published case series describe harm from large amounts and mostly mild courses. [2][3][4]
  • FDA, EFSA, EMA, WHO and NCCIH: we did not open a statement from any of these for nutmeg, so we cite none.

Related pages

SpiceMyristica fragrans

Health connections for Nutmeg

What research links to this spice, and how strong the evidence is. Most studies use concentrated extracts or doses far above what you eat; each card says which.

Painful diabetic nerve symptoms (skin product)

Preliminary or mixed

In a 74-person randomized trial, a skin product with nutmeg and mace oils did not improve pain beyond the comparison product after 4 weeks.

Supplements: No added benefit in this trial; topical only, not a food or supplement finding.

Antioxidant, antidiabetic and anticancer effects in cells and animals

Lab or animal research only

A 2025 review describes these effects in lab and animal work and says more clinical research is needed.

Supplements: Lab and animal only; no human supplement benefit shown.

Digestive use in traditional medicine

Not enough evidence

Traditional use for digestion is not backed by any trial we read.

Supplements: No evidence for food or supplements.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Body systems (5)
  • Nervous SystemDocumented risk

    Large amounts have caused delirium, agitation and drowsiness in poison-center and case reports.

  • Hepatic / Liver SystemDocumented risk

    Liver changes were seen in rats at very high amounts; not shown in people.

  • Kidney & UrinaryDocumented risk

    Kidney damage in rats at the higher very high amount; not shown in people.

  • Liver & DetoxDocumented risk

    Liver changes in rats at very high amounts; not shown in people.

  • Urinary SystemDocumented risk

    Kidney damage in rats at the higher very high amount; not shown in people.

Body parts (4)
  • BrainDocumented risk

    Large amounts can cause delirium and an altered level of consciousness.

  • Nervous SystemDocumented risk

    Large amounts have caused agitation, drowsiness and seizures in reports.

  • KidneysDocumented risk

    Kidney damage in rats at the higher very high amount.

  • LiverDocumented risk

    Liver changes in rats at very high amounts.

Conditions & symptoms (3)
  • DeliriumDocumented risk

    A case report describes severe agitated delirium after excessive nutmeg ingestion.

  • Poisoning SyndromeDocumented risk

    Poison-center series describe intentional and accidental poisonings with large amounts.

  • Diabetic Peripheral NeuropathyPreliminary or mixed

    A trial of a skin product with nutmeg and mace oils showed no added benefit over the comparison product.

Documented risks and interactions (5)
  • Poisoning from large amounts. Poison-center series and case reports describe fast heartbeat, wide pupils, drowsiness, confusion and sometimes severe agitation after swallowing large amounts of nutmeg or mace.
  • Accidental exposure in children. In Illinois, more than half of accidental exposures were in children under 13; a six-year-old who ate six pieces of mace needed hospital care.
  • Possible link to mood medicines. A case report notes myristicin moderately inhibits monoamine oxidase; a man on fluoxetine and quetiapine had a mild course after a very large ingestion.
  • Liver and kidney changes at very high amounts (rats). Rats given nutmeg powder for 90 days at very high amounts had liver and spleen changes, and kidney damage at the higher amount.
  • Pregnancy caution for large amounts. One general reference calls flavoring amounts safe and advises avoiding large amounts in pregnancy.

Explore all 80 spices

Frequently asked questions

Is nutmeg sweet?

It tastes warm and slightly sweet, with a pungent smell. [1] Mace is more delicate. [1]

How much is normal?

USDA lists 2.2 g per teaspoon of ground nutmeg. [10] We found no official recipe amount. A pinch in a dish is normal; large amounts have caused poisoning. [4]

Is it safe in pregnancy?

One reference calls flavoring amounts safe and advises avoiding large amounts. [1] Ask your midwife or doctor.

Can I take it with medicines?

The sources we read do not give a clear answer. Myristicin may affect an enzyme that some mood medicines also act on. [5] Ask a pharmacist.

What happens if someone eats too much?

Reports describe fast heartbeat, wide pupils, sleepiness, confusion and sometimes severe agitation. [4][6] Call your poison center, or emergency services if the person is hard to wake.

Does nutmeg have health benefits?

Lab studies are interesting, but we found no human trial showing a benefit when it is eaten. [9] A trial of a skin product for diabetic nerve symptoms showed no added benefit. [7]

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety note at a glance
A pinch in food is fine, but a spoonful or more swallowed at once has caused real poisonings, especially in children and teenagers. If someone has swallowed a large amount, call your poison center (US: 1-800-222-1222). [2][3][4]
Safety in more detail
  • Medicines: a man on fluoxetine and quetiapine who swallowed 75 g of nutmeg had a mild course. [4] A case report notes that myristicin moderately inhibits monoamine oxidase, an enzyme that some mood medicines also act on. [5] The sources we read do not show whether this matters at cooking amounts. Ask a pharmacist.
  • Pregnancy: one general reference calls flavoring amounts safe and advises avoiding large amounts. [1] We did not find a stronger source.
  • Breastfeeding: the sources we read do not describe breastfeeding.
  • Children: in Illinois, more than half of accidental exposures were in children under 13, and a six-year-old who ate six pieces of mace became very drowsy and needed hospital care. [2][5]
  • Allergy: the sources we read do not describe nutmeg allergy.
  • Liver and kidney: only rat findings at very high amounts were found. [8] A review notes liver and kidney effects at high doses. [9]
  • Surgery: the sources we read do not describe a surgery warning.
  • Quality and contamination: the sources we read do not describe any.
  • Amounts that cause trouble: the sources we read give no single safe or toxic amount. The Swiss case involved 75 g, far beyond a recipe. [4] Most poison-center cases were mild: none of 17 Texas calls led to more than moderate effects. [3] Severe cases exist, including a young adult with severe agitation who needed a breathing tube. [6] Swiss calls rose in 2020 and 2021, linked by the authors to a social media "nutmeg challenge". [4]
References
  1. Wikipedia — Nutmeg. https://en.wikipedia.org/wiki/Nutmeg (accessed 2026-10-24)
  2. Nutmeg poisonings: a retrospective review of 10 years experience from the Illinois Poison Center, 2001-2011. J Med Toxicol 2014; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/24452991/ (accessed 2026-10-24)
  3. Nutmeg intoxication in Texas, 1998-2004. Hum Exp Toxicol 2005; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/16323572/ (accessed 2026-10-24)
  4. Intoxication with nutmeg: a case presentation and analysis of Swiss poisons information center enquiries 2014-2023. Toxicol Rep 2026; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/42205531/ (accessed 2026-10-24)
  5. Mace poisoning: accidental toxic ingestion in a child leading to a reversible coma. Cureus 2024; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/39850188/ (accessed 2026-10-24)
  6. Nutmeg intoxication: a case report. Cureus 2023; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/37915877/ (accessed 2026-10-24)
  7. Nutmeg extracts for painful diabetic neuropathy: a randomized, double-blind, controlled study. J Altern Complement Med 2013; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/23098698/ (accessed 2026-10-24)
  8. Safety of nutmeg powder by oral exposure: toxicity prediction and in vivo evaluation. Food Chem Toxicol 2025; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/40024564/ (accessed 2026-10-24)
  9. Nutmeg beyond spice: a review on its therapeutic potential, safety and industrial promise. 2025; abstract read via Europe PMC. https://pubmed.ncbi.nlm.nih.gov/41104350/ (accessed 2026-10-24)
  10. USDA FoodData Central, SR Legacy (April 2018) — Spices, nutmeg, ground (fdcid 171326) and Spices, mace, ground (fdcid 170927), per-100 g values and household portions from the site's USDA data file.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.