Liver
Nutrients connected to Liver
A link means the body needs the nutrient for this, or that low intake is linked to it. It does not mean extra supplements help if your intake is already adequate; each link shows how strong the evidence is.
- Curcumin (turmeric supplements)Documented risk
Liver injury has been reported with turmeric or curcumin supplements, especially highly absorbable products; stopping the product is advised if symptoms appear. Early research on fatty liver measures is also mixed.
- Green tea extract and EGCGDocumented risk
EFSA found trials of 800 mg or more EGCG a day as a supplement raised liver enzyme markers; this describes trial results, not a recommended amount.
Phosphatidylcholine made from choline carries fat out of the liver; low choline led to liver fat and raised liver enzymes in studies.
- AshwagandhaDocumented risk
Case series document supplement-linked liver injury, usually cholestatic or mixed and often reversible after stopping.
- TurmericDocumented risk
Liver injury has been reported with turmeric products, especially those made to be absorbed better. A US case series described mostly liver-cell injury starting about 1 to 4 months after use began, with one death. Stop and see a provider for dark urine, yellow skin or eyes, nausea or fatigue.
- Aloe veraDocumented risk
NCCIH reports cases of acute hepatitis linked to oral aloe leaf extracts, and two published case reports describe it. Case reports show a possible link, not how common it is.
- Gotu kolaDocumented risk
Case reports link oral gotu kola to hepatitis and jaundice; how often is unknown.
- NoniDocumented risk
Liver injury has been reported after drinking noni juice or tea for several weeks; it is unclear whether noni was the cause.
- Black cohoshDocumented risk
Rare cases of liver damage have been reported; stop and seek care for dark urine, yellow skin or eyes, or severe upper stomach pain.
- ButterburDocumented risk
The raw plant contains pyrrolizidine alkaloids that can damage the liver, and rare liver injury has been reported even with products labeled PA-free.
- ComfreyDocumented risk
Comfrey taken by mouth is linked to liver injury through its pyrrolizidine alkaloids; this is a risk, not a benefit.
- Guduchi (giloy)Documented risk
LiverTox and a 43-patient Indian study describe clinically apparent liver injury after guduchi use, often within about 46 days. Some authors argue a look-alike species may be to blame.
- He shou wuDocumented risk
Reports and case series link this root to liver injury, so it is a liver risk rather than a liver aid.
- KavaDocumented risk
Kava products have been linked to rare but serious or fatal liver injury, including liver failure needing transplant. Memorial Sloan Kettering says the liver risk outweighs any benefits.
- WormwoodDocumented risk
The EU monograph lists liver disease and bile duct disease as reasons not to use wormwood, and a 2025 report describes toxic hepatitis after large amounts. This is a caution, not a benefit.
- BupleurumDocumented risk
The liver is the main organ affected in reported bupleurum toxicity; animal studies of protection do not show benefit in people.
- CorydalisDocumented risk
Liver injury has been reported in people using corydalis products, and animal studies describe liver damage at high amounts of raw extract. How often it happens is not known.
- Reishi (lingzhi)Documented risk
Liver injury has been reported with reishi, mostly with powders, including one fatal case. People with liver disease should ask a clinician before using it.
- Almond mushroom (Agaricus subrufescens)Documented risk
Case reports link Agaricus blazei extracts to severe liver injury in people with cancer, including two deaths. Frequency is unknown.
- ColtsfootDocumented risk
Coltsfoot can contain pyrrolizidine alkaloids, which damage the liver; the EU herbal committee describes blocked liver veins and cirrhosis from toxic PAs.
- PennyroyalDocumented risk
Swallowed pennyroyal oil or tea has caused severe liver injury, liver failure and death.
- RueDocumented risk
Swallowed rue has been linked to liver impairment and, in severe cases, multi-organ failure. A safety caution, not a benefit.
- TansyDocumented risk
Liver inflammation and damage are listed as possible poisoning effects.
- Garcinia cambogiaDocumented risk
NCCIH and a 2025 review describe liver injury reports with Garcinia products, including severe cases, a death and liver transplants. Most cases involved other products or medicines, so the true risk is uncertain.
- Sweet wormwood (Artemisia annua)Documented risk
Case reports and a regulator's alert link Artemisia annua tea and extract supplements to liver inflammation.
- Calamus (sweet flag)Documented risk
Asarone caused liver cancer in rodents (EMA); human liver data were not found in the sources read.
- Usnea (old man's beard lichen)Documented risk
Usnic acid supplements have been linked to acute hepatitis and liver failure, including transplants and a death. Serious safety problem.
- TurmericDocumented risk
Liver injury has been reported with turmeric and curcumin supplements, especially highly absorbable forms; this is a safety link, not a benefit.
- Bakuchi (babchi)Documented risk
Published case reports link bakuchi products to liver injury.
- Gardenia fruit (zhi zi)Documented risk
High doses of geniposide injured the liver in rats. No human trial or case report was found, and some animal studies report liver-protective effects, so the picture is mixed.
- Xanthium (cang er zi, cocklebur)Documented risk
Liver necrosis in poisoned cattle and liver injury in mice and in a human case.
- Horse mushroomDocumented risk
The deadly death cap, reported to be confused with horse mushroom, causes liver failure after a delay of many hours.
- Gravel root (Joe-Pye weed)Documented risk
A consumer drug reference warns that gravel root may contain liver-toxic pyrrolizidine alkaloids; close relatives do, but gravel root itself was not analysed in the sources read.
- Death capDocumented risk
Amatoxins destroy liver cells and cause acute liver failure.
- Destroying angelDocumented risk
Amatoxins in destroying angels damage liver cells; acute liver failure and transplant are reported.
- False MorelDocumented risk
Liver injury occurred in 53.7% of published ingestions and 16.9% of symptomatic Michigan cases.
- Funeral bellDocumented risk
Amatoxins from the funeral bell group destroy liver cells and can cause liver failure; this is a poisoning, not a benefit.
- Greater celandineDocumented risk
Case series describe liver-cell injury with jaundice, usually improving after the herb is stopped; the cause is not established.
- Chaparral (creosote bush)Documented risk
Chaparral products have been linked to serious liver injury, some needing a transplant.
- SassafrasDocumented risk
Safrole caused liver tumors in rats and mice, and the US National Toxicology Program lists it as reasonably anticipated to be a human carcinogen. This is a documented risk, not a benefit.
- Sophora flavescens (ku shen)Documented risk
Studied for hepatitis B and also linked to liver toxicity of matrine in animal and cell studies.
- BorageDocumented risk
Borage leaf and flower contain liver-toxic pyrrolizidine alkaloids; borage oil should be used only if certified free of them, and not by people with liver disease (Memorial Sloan Kettering, EU committee).
- Thunder god vineDocumented risk
Liver problems are listed by NCCIH; animal studies show liver injury from triptolide.
- Deadly parasolDocumented risk
Amatoxins destroy liver cells and can cause acute liver failure; explanted livers in the Iranian series showed massive necrosis.
- Cinnamon twig (gui zhi)Documented risk
Cassia cinnamon contains coumarin, and liver interactions have been reported; people with liver disease should be careful. Twig amounts were not found.
- Sheathed woodtuftDocumented risk
Caused by amatoxins in the funeral bell, a deadly look-alike reported to be confused with sheathed woodtuft; not by sheathed woodtuft itself.
- Clove OilDocumented risk
Swallowed clove oil caused severe liver failure in infants and toddlers in case reports; LiverTox says overdose can cause severe liver injury.
- Pennyroyal Oil (Dangers)Documented risk
Pulegone and its breakdown products affect the liver in poisoning cases.
- Comfrey and Coltsfoot TeasDocumented risk
Veno-occlusive liver disease after PA-containing teas, including a fatal adult case and a child who recovered.
- Kava, Kratom and Blue Lotus TeasDocumented risk
NCCIH links kava products, including water beverages, to rare serious or fatal liver injury; FDA lists liver toxicity among kratom warnings.
- Pennyroyal Tea (Dangers)Documented risk
Liver failure is the best-documented harm, including in infants.
- Wormwood Tea (Dangers)Documented risk
Toxic hepatitis with one death after liver transplant was reported.
- Fat Burners and Weight-Loss BlendsDocumented risk
Case reports and a US outbreak investigation link weight-loss supplements to liver injury; exact ingredients were often unclear.
- Vitamin ADocumented risk
The liver stores vitamin A, and very high levels are linked with an enlarged liver. Liver foods are very rich sources.
- Vitamin KEstablished role
The liver uses vitamin K to make clotting factors II, VII, IX and X.
- Vitamin B3 (niacin)Documented risk
Long-term high doses could lead to liver damage.
- IronDocumented risk
Too much iron in haemochromatosis builds up and can damage the liver.
- CopperDocumented risk
Long-term high doses of copper can damage the liver, and in Wilson disease copper builds up there.
- N-acetylcysteineClinically supported
Acetylcysteine is a hospital antidote for paracetamol overdose, given by clinicians. Supplements are not a substitute, and evidence for liver benefit in healthy people was not found.
- DandelionDocumented risk
The EU herbal committee lists liver disease as a reason not to use dandelion root with herb. Dandelion has not been shown to protect the liver.
- RosemaryDocumented risk
Liver disease needs medical supervision before using rosemary leaf by mouth, per the EU monograph.
- Artichoke leafDocumented risk
The EU monograph excludes people with liver disease from self-use. A small pilot trial in fatty liver reported better liver tests but is not confirmed.
- CinnamonDocumented risk
Coumarin in cassia cinnamon and the liver: caution with prolonged use and liver disease.
- Milk ThistlePreliminary or mixed
Milk thistle is traditionally used for the liver, but NIH says trial results in liver disease are conflicting or too limited for firm conclusions, and two NIH-funded trials (hepatitis C and fatty liver with inflammation) showed no benefit.
- Pelargonium (Umckaloabo)Documented risk
Liver problems have been reported, frequency not known; whether the plant caused them is disputed. Stop and see a doctor if liver warning signs appear.
- SkullcapDocumented risk
Linked to clinically apparent liver injury in several instances, usually alongside other botanicals.
- TribulusDocumented risk
Case reports of severe liver injury; individual cases only.
- RooibosDocumented risk
Case reports link rooibos to liver problems (raised enzymes, liver injury); rare, and usually improved after stopping.
- Horny goat weedDocumented risk
Two Epimedium-leaf products have been linked to liver injury in people.
- Baikal skullcapDocumented risk
Liver injury that settled after stopping and returned on restarting has been reported; about 1 in 1,000 treated people had confirmed injury in one hospital study.
- BonesetDocumented risk
All 49 boneset samples tested contained pyrrolizidine alkaloids, a compound family linked to liver disease; human liver injury from boneset itself was not found in the sources read.
- KratomDocumented risk
Case reports link kratom to liver injury, mostly cholestatic; 4 of 32 published cases needed a transplant.
- Honey mushroomDocumented risk
Same point: the deadly look-alike damages the liver; honey mushroom is not known to.
- Antrodia camphorataPreliminary or mixed
The most studied target; small trials with mixed results.
- Bayberry (wax myrtle)Documented risk
Consumer references list liver damage as a possible effect of swallowed bayberry. A safety caution, not a benefit.
- LungwortDocumented risk
Possible exposure to liver-toxic pyrrolizidine alkaloids; unquantified for lungwort products.
- Black pepperDocumented risk
Piperine affects liver enzymes that break down drugs; clinical importance must be assessed.
- CinnamonDocumented risk
Coumarin in cassia and the liver.
- Chitrak (Ceylon leadwort)Documented risk
Liver was a main target organ in rat studies and a review lists liver damage.
- ClovesDocumented risk
Clove oil caused liver damage in toddlers; this is about the oil, not the spice in cooking.
- Kutaja (kurchi)Documented risk
A three-month rat study of an extract found liver damage at doses far above the human dose; no human liver data was read.
- SpirulinaDocumented risk
Cyanotoxin contamination of supplements is a documented liver risk; liver injury from spirulina itself is described as very rare.
- BoldoDocumented risk
Case reports describe liver injury after boldo tea, and the EU contraindicates boldo in liver disease.
- EpazoteDocumented risk
TRAMIL contraindicates oral use in liver disease and lists liver damage among effects of the oil.
- Japanese knotweed (hu zhang)Documented risk
Emodin in the root could harm the liver at high doses and with long-term use, based on lab and animal work. Human safety data for the root were not found.
- Evodia (wu zhu yu)Documented risk
A 2025 review calls the fruit mildly toxic and says it has obvious toxic effects on the human liver; animal and cell studies show liver damage. Details of human cases were not read.
- Bitter leafDocumented risk
Fatal liver failure reported in a case after use to end a pregnancy. One case cannot prove cause.
- KhatDocumented risk
One Ethiopian hospital study found a dose-related link with chronic liver disease.
- WatercressDocumented risk
Wild watercress can carry liver-fluke larvae that settle in the liver and bile ducts (CDC).
- Sweet clover (melilot)Documented risk
Melilot contains coumarin, which is liver-toxic at high doses; human liver reports are mostly at higher daily amounts and some people seem more sensitive. People with liver disease should ask first.
- FumitoryDocumented risk
EMA advises against fumitory with liver disease, and one acute hepatitis case was reported with a fumitory-containing multi-herb product.
- Cassia seed (jue ming zi)Documented risk
Rat studies and a cited case analysis link cassia seed extracts and their anthraquinones to liver injury. Human risk from tea is unknown.
- Capillary wormwood (yin chen hao)Preliminary or mixed
Used in Chinese medicine for jaundice and liver complaints. Human trials are of the three-herb formula and small and short; single-herb evidence is lab and animal only. Case reports also link Yin Chen Hao to liver injury.
- WatercressDocumented risk
Wild watercress can carry liver fluke larvae; the parasite infects the liver and bile ducts.
- Taxillus (sang ji sheng)Documented risk
A 2022 review says the plant shows liver toxicity and may cause complications in people with liver disease; supporting data were not found in the part we read.
- Deadly ConocybeDocumented risk
Amatoxins, the toxins reported in this species, cause liver damage; no human case of this species was found, so the course is taken from amatoxin poisoning in general.
- Sweet woodruffDocumented risk
Large amounts of coumarin over a long period can affect the liver in sensitive people (AGES, BfR). Reversible after stopping in the case AGES describes.
- Autumn crocus (colchicum)Documented risk
Liver impairment is described after autumn crocus poisoning.
- Tonka beanDocumented risk
Coumarin liver effects in animals and in a small subgroup taking it as a drug; usually reversed after stopping.
- PeanutsDocumented risk
Aflatoxin exposure from contaminated peanuts is linked to liver cancer.
- Nut & Seed Butters (overview)Documented risk
Aflatoxin from moldy peanuts is a liver toxin and a liver cancer risk per WHO.
- Green TeaDocumented risk
Extract at 800 mg EGCG a day or more raised liver blood tests; the drink is judged generally safe, with rare reports.
- Rooibos TeaDocumented risk
Three liver case reports are described by MSK.
- Rosemary TeaDocumented risk
EU precaution for liver disease; no liver injury from the tea is reported in the sources we read.
- Skullcap TeaDocumented risk
Liver injury reports (LiverTox) and germander adulteration.
- Ashwagandha TeaDocumented risk
Liver injury reports with supplements.
- Turmeric TeaDocumented risk
Liver injury reports (DILIN, Italy) involve supplements.
- Cinnamon TeaDocumented risk
Coumarin hepatotoxicity in animals and sensitive people; LiverTox notes rare cinnamon reports.
- Chai (Spiced Tea Blend)Documented risk
NCCIH says prolonged use of cassia could be an issue for people with liver disease.
- Cassia OilDocumented risk
Coumarin in cassia cinnamon has been linked to liver problems in reports (NCCIH); the oil's coumarin content is not described in the sources read.
- Blue-Green Algae (AFA)Documented risk
Microcystins are liver toxins; MSK says contaminated products may cause liver damage.
- Children's MultivitaminsDocumented risk
Iron overdose can cause severe liver damage 2 to 5 days later.
- Joint Formulas (Glucosamine, Chondroitin, MSM, Turmeric)Documented risk
Turmeric supplement liver injury reports.
- Mushroom Blends and Mushroom CoffeeDocumented risk
Reishi powder with alcohol: acute hepatitis case report.
- Vitamin DEstablished role
The liver helps convert vitamin D to a usable form, so liver disease can affect vitamin D status.
- Vitamin B12Established role
The liver stores a few years' worth of B12.
- ChromiumDocumented risk
Isolated cases of liver impairment have been reported with chromium supplements.
- BCAAs (leucine, isoleucine, valine)Preliminary or mixed
Studied in cirrhosis with hepatic encephalopathy (low-certainty evidence, medical setting). Not advice for healthy people.
- CarnitineDeficiency link
In rare inherited carnitine disorders, findings include liver disease. These need medical care.
- CreatineEstablished role
The liver is one of the two organs that make creatine from arginine, glycine and methionine. Liver enzyme markers showed no clinically important change in the studies reviewed.
- Beta-alanineDocumented risk
Small average ALT rise in studies, within reference ranges; ask a clinician if you have liver disease.
- Coenzyme Q10Documented risk
Raised liver enzymes have been reported with CoQ10; people with liver conditions should ask a clinician first.
- FennelDocumented risk
The EU monograph notes estragole caused liver tumors in mice; human risk at normal tea use is not established, which is why intake limits are set.
- Saw palmettoDocumented risk
Single case reports describe severe liver damage in people taking saw palmetto. How often this happens is not known.
- SennaDocumented risk
Rare liver injury at high doses over long periods (as reported on the site page).
- ValerianDocumented risk
Rare liver injury has been reported, most often with other herbs.
- SchisandraPreliminary or mixed
The fruit is used traditionally for the liver; small human studies are limited. It also lowers ALT and AST on tests.
- Willow barkDocumented risk
Not for severe liver dysfunction; single fatal case report.
- Asian ginsengDocumented risk
Liver damage is an uncommon reported effect.
- HorsetailDocumented risk
Case reports of hepatitis after horsetail use exist; cause is uncertain.
- Witch hazelDocumented risk
Rare liver damage reported with long-term oral use of tannin-rich products.
- EucalyptusDocumented risk
Cineole may speed up liver enzymes that break down medicines, and the German Commission E (cited by the EMA) lists impaired liver function as a reason not to use the oil. No LiverTox entry was found.
- BhringrajLab or animal research only
Rat studies suggest extracts may lessen chemically caused liver damage. No human studies were reported in the review we read.
- ForsythiaLab or animal research only
Ripe-fruit extract eased bile-duct-blockage liver injury in rats; no human evidence.
- BuchuDocumented risk
High-dose buchu oil harmed rat livers (pulegone) and one liver-failure case followed a rooibos-buchu tea, but LiverTox reports no linked injury in people. Sources conflict.
- Graviola (soursop)Documented risk
Cancer Research UK says frequent use may damage the liver; a graviola acetogenin caused liver toxicity in a rodent model. No human cases found.
- BaelDocumented risk
Reviews report liver protection in animals only. Separately, a 2013 multi-ingredient supplement outbreak caused liver injury; the ingredient was not named.
- KutkiPreliminary or mixed
One small 1996 trial in acute viral hepatitis reported benefit; other human studies are small, mostly open-label formula studies. Most evidence is from animals, so it is not an established liver treatment.
- Fadogia agrestisLab or animal research only
A rat study reported enzyme changes and cell-membrane stress in liver tissue; no human data were found.
- Houttuynia (yu xing cao)Lab or animal research only
Liver changes at high extract amounts in rats.
- Pioppino (black poplar mushroom)Documented risk
Same mouse finding: lectin AAL was toxic to the liver in a raw extract. Human relevance not shown.
- Paddy straw mushroomLab or animal research only
Liver-protection findings come from mice and cells only.
- Grains of paradiseDocumented risk
A 28-day rat study of a strong extract raised liver weight; authors said liver toxicity should be considered. Human significance unknown.
- NutmegDocumented risk
Liver changes in rats at very high amounts.
- Angelica pubescens (du huo)Documented risk
Reversible liver changes in rats and dogs and liver damage with isolated xanthotoxin in animals; no human data in the reviews read.
- Bay leafDocumented risk
A 2026 case report links months of regular bay leaf tea to probable herb-induced liver injury in one woman, who improved after stopping. One case does not show cause for everyone.
- King tuber mushroomLab or animal research only
Rat studies of chemically induced liver damage.
- CarawayDocumented risk
The EU committee does not recommend caraway medicines in liver disease, cholangitis, gallstones or other bile-duct disorders.
- Apricot kernel (bitter)Documented risk
NCI lists liver damage among the effects of laetrile, which releases cyanide.
- Thuja (northern white cedar)Documented risk
One case report linked thuja plus black cohosh to probable liver injury; the evidence is weak and the herb responsible is unclear.
- Lion's tail (wild dagga)Documented risk
Rat studies of water extracts reported changes in liver-related blood tests; no human data.
- Papaya leafDocumented risk
Animal studies showed raised liver enzymes with repeated dosing and two unpublished human reports described raised transaminases; caution in liver impairment.
- Mistletoe (European)Documented risk
One review found high doses of injected extract damaged the liver in some cases, reversibly.
- Ras el hanoutDocumented risk
Liver effects are described for highly absorbable curcumin supplements and for cassia coumarin, not for the blend itself.
- KokumDocumented risk
No research directly links kokum to acute liver injury, but it contains HCA and garcinia supplements have liver reports, so liver effects need study.
- Mahlab (mahleb)Documented risk
Coumarin in the kernel is the compound behind the liver limit; applies to large daily intakes, not a pinch in baking.
- Saptaparna (devil's tree)Lab or animal research only
In rats given a bark extract for 28 days, liver cells showed damage and liver enzymes rose. Human liver data were not found.
- Amanita smithiana and Amanita proximaDocumented risk
Mild, short-lived liver enzyme rises are reported; the related syndrome is called mild hepatitis.
- Sweet CornDocumented risk
Aflatoxin from moldy or contaminated corn can harm the liver and raise liver cancer risk with regular intake (FDA).
- Pueraria mirifica (kwao krua)Documented risk
Mild fat change in rat liver cells at high amounts; short-lived liver lab changes in a few women in small studies.
- Filé powder (ground sassafras leaf)Documented risk
Safrole from sassafras root and oil caused liver cancer in lab animals; the concern is not shown for filé eaten as food, and one 1997 FDA test found safrole below detection in most leaf samples.
- Lotus SeedsDocumented risk
Aflatoxin contamination in lotus seeds; aflatoxins damage the liver in large doses and raise liver cancer risk with regular intake.
- AcornsDocumented risk
A 2026 study says raw acorn tannins may cause liver toxicity; the animal source describes liver injury at higher doses. No human cases were read.
- Cinnamon Oil (Leaf and Bark)Documented risk
NCCIH says coumarin in cassia cinnamon has been reported to affect the liver; stated for cassia products, not the oil.
- Camphor Oil (Dangers)Documented risk
Camphor is listed among liver-toxic terpenes in a review.
- MatchaDocumented risk
Extract at 800 mg EGCG a day or more raised liver tests; matcha was not tested.
- Spearmint TeaLab or animal research only
Rats given spearmint tea for 30 days had raised liver enzymes and liver tissue damage. Animal only.
- Lemongrass TeaDocumented risk
LactMed: rare liver toxicity reports.
- Ginseng TeaDocumented risk
Liver damage reports (NIH); cohort signal for ginseng tea in liver disease.
- Valerian TeaDocumented risk
Rare liver injury reports (NIH, LiverTox).
- Fennel TeaDocumented risk
Estragole in fennel caused liver tumors in mice; the EU asks for exposure to be kept as low as practically achievable. No liver harm in people from fennel tea was shown in the sources we read.
- Milk Thistle TeaPreliminary or mixed
Traditional use for the liver; extract trials gave mixed results, a meta-analysis found changes in liver enzymes without clinical relevance. Not shown for the tea.
- Senna Tea (Laxative Teas)Documented risk
One case report of liver failure after very heavy, long use of senna fruit tea. A single case; rare.
- SenchaDocumented risk
Liver injury is uncommon and linked mainly to green tea extracts; EFSA noted rare reactions to infusions.
- GyokuroDocumented risk
Liver injury is uncommon and linked mainly to green tea extracts; EFSA noted rare reactions to infusions.
- Moroccan Mint TeaDocumented risk
Liver injury from green tea is uncommon and mainly linked to extracts; EFSA noted rare cases after infusions. Spearmint tea raised liver enzymes in rats.
- Kombucha (Fermented Tea)Documented risk
Case reports describe liver injury after kombucha. They cannot show cause or frequency.
- Cumin, Coriander and Fennel (CCF) TeaDocumented risk
Estragole in fennel caused liver tumors in mice and the EU asks that exposure be kept low. No human harm from fennel tea was shown in the sources read.
- CoffeePreliminary or mixed
Observational studies link coffee with lower liver cancer risk.
- Korean Red GinsengDocumented risk
NCCIH lists liver damage as an uncommon report.
- Creatine in Food (Meat and Fish)Established role
The liver is one of the two organs that make creatine from arginine, glycine and methionine.
- B-Complex FormulasDocumented risk
The NHS says long-term high doses of nicotinic acid may damage the liver; MedlinePlus lists liver damage with high niacin intake.
- Whey Protein PowderDocumented risk
A systematic review names the liver among organs affected by chronic, heavy, unsupervised use; people with liver disease should ask a clinician first.
- Sleep Blends (Melatonin, Magnesium, L-Theanine, Herbs)Documented risk
Rare liver injury has been reported with valerian and kava.
- Greens PowdersDocumented risk
Liver injury is uncommon but reported with green tea extracts, mainly in tablet or capsule form; relevant only if a powder lists them.
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