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A clear glass cup of pale yellow-green green tea beside a small pile of dried green tea leaves
Green tea: the brewed drink and the dried leaf.

Herbal Teas & Extracts · Tea

Green Tea

Camellia sinensis · also called Green tea, tea (unfermented tea leaf). Not the same as green tea extract capsules.

Green tea is a drink made from the leaves of the tea plant, steamed or pan fried and dried but not fermented. People drink it for heart health, weight, focus and general wellbeing. Research shows small or uncertain effects at best, and most trials mix the drink with extracts. The drink has no safety concerns reported for adults apart from its caffeine, but concentrated extract capsules have been linked to rare serious liver injury.

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About Green Tea

Green tea is the drink from unfermented tea leaves. Research gives small or uncertain results for heart risk factors, almost nothing for weight or cancer, and no effect on blood sugar in trials. NCCIH reports no safety concerns for the drink in adults beyond caffeine. Concentrated extract capsules are a separate product: they have been linked to rare serious liver injury and should not be judged by tea results.

What it is

Green tea comes from the leaves of Camellia sinensis, a plant of the tea family (Theaceae) that GBIF accepts as a species. Green, black and oolong teas all come from this same plant and differ in how the leaves are processed. For green tea the leaves are steamed or pan fried and dried but not fermented.

The drink contains caffeine, L-theanine and catechins, mainly EGCG. Matcha is the whole leaf ground to powder, and extract capsules are concentrated catechins; each is a different product.

31 25 28 29 30

Tea, matcha or extract?

A cup of green tea is a weak water extract of the leaf. A capsule or tablet packs catechins into a concentrated pill. The liver warnings and many trial results belong to the concentrated form. A systematic review of 159 human studies found liver events came from concentrated, catechin-rich preparations taken in large single doses, and not from brewed tea or extracts used in drinks or food. Do not carry results from one form to the other.

8 4 25

What the research shows

Cochrane found small falls in cholesterol and blood pressure from a few green tea trials, but the results were not stable and no trial reported heart attacks or strokes. A later review of 14 shorter tea trials found no effect on lipids or blood pressure. Outside Japan green tea gave almost no weight loss.

Cochrane found inconsistent, low-certainty results for cancer. In eight Japanese cohorts, heavy drinkers had lower death rates, which shows a link and not a cause. For thinking, one review of mixed studies suggests a role for caffeine and L-theanine together. Trials of green tea supplements in type 2 diabetes found no effect on blood sugar.

6 10 12 5 1 14 3 18 22

Fluoride and brewing

Tea plants take up fluoride from the soil, and longer brewing releases more. A review of 88 studies found average fluoride was lower in green tea than in black or brick tea. Fluoride matters most for young children and very heavy tea drinkers. One lab study of Turkish green tea found 3 minutes in 85 C water gave the most EGCG with the best taste, but that is one tea and not a rule. No measured lead, cadmium or pesticide figures for green tea were found in the sources read.

11 19 20

Regulators and status

The EMA has an EU herbal monograph and assessment report for green tea leaf; only the web page was read. EFSA judged traditional infusions generally safe at European intakes. NCCIH notes that the FDA approved a green tea extract ointment as a prescription drug for genital warts, which is a topical medicine and not a drink or supplement.

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At a glance

Traditional uses history, not proof

  • Tea was first grown in China thousands of years ago, and NCCIH says it has been used for health purposes for about 3,000 years.
  • Today green tea and its extracts are promoted as supplements for weight loss, lower cholesterol and prevention of chronic disease (NCCIH).
  • The European Medicines Agency has an EU herbal monograph for green tea leaf (therapeutic area listed as fatigue and weakness).

Studied for research

  • Cholesterol, low
  • Blood pressure, low
  • Body weight, low
  • Heart disease and death rates in drinkers (an association), low
  • Attention, memory and mood, low
  • Cancer risk, insufficient
  • Dementia risk, very low
  • Blood sugar in type 2 diabetes, no effect found (against)

Main compounds

  • Catechins, mainly EGCG
  • Caffeine
  • L-theanine
  • Tannins and other polyphenols

Common forms

  • Brewed tea from loose leaf or tea bags
  • Matcha (whole leaf powder, separate page)
  • Bottled and iced green tea
  • Concentrated extract capsules and tablets (a different product with a liver warning)

Research links: NCCIH: Green Tea · EFSA opinion on green tea catechins (abstract) · Cochrane: green tea and heart disease prevention (abstract) · Cochrane: green tea and cancer prevention (abstract) · LiverTox: Green Tea (summary) · FDA: How much caffeine is too much · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Camellia sinensis
Naming authority
(L.) Kuntze
Synonyms
Camellia bohea (L.) Sweet; Camellia chinensis (Sims) Kuntze; Camellia cantonensis Lour.
Common names
Green tea (English); Tea (English)
Family or group
Theaceae (the tea family)
Classification
Plantae > Ericales > Theaceae > Camellia > Camellia sinensis
Native range
Not checked in the sources read (NCCIH says tea was first cultivated in China thousands of years ago).
Habitat
Not checked.
What it looks like
Stems: Stems are present in some tea products (LactMed).; Leaves: The leaf is the part used; steamed, pan fried and dried but not fermented for green tea (NCCIH).; Flowers: Not checked.; Fruit: Not checked.
Cultivation
Not checked.
Harvest and processing
Green tea leaves are steamed, pan fried and dried but not fermented. Black tea is fermented and oolong partly fermented (NCCIH).
Look-alikes and adulterants
Name: Green tea extract and other tea types; Note: Matcha, black tea and oolong come from the same plant but are different products; extract capsules are concentrated and behave differently from brewed tea.
Sustainability and conservation
Not checked.

Photographs

A clear glass cup of pale yellow-green green tea beside a small pile of dried green tea leaves
Green tea: the brewed drink and the dried leaf.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
China, early useNCCIH says tea was first cultivated in China thousands of years ago and that tea was used for health purposes for about 3,000 years.s-nccih-green-tea
European herbal medicineEMA has an EU herbal monograph and assessment report for green tea leaf (Camelliae sinensis non fermentatum folium) with therapeutic area "Fatigue and weakness". The wording of the monograph was not read.s-ema-hmpc-green-tea
TodayNCCIH says green tea and extracts are promoted as supplements for weight loss, lower cholesterol and prevention of chronic disease, and that the FDA approved a topical green tea extract ointment for genital warts.s-nccih-green-tea

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
Epigallocatechin gallate (EGCG)
PubChem 65064
catechin (polyphenol)Leaf
The main catechin in green tea (EFSA). One lab study measured it in a Turkish green tea brew; the amount depends on brewing.
Liver effects at high supplement doses; other actions not established in the sources read. 28 4 20Human data
Caffeine
PubChem 2519
purine alkaloidLeaf
37 mg per 12 fl oz drink (FDA).
Stimulant; see Safety tab. 29 24Human data
L-theanine
PubChem 439378
amino acidLeaf
Not given in the sources read.
Reviewers link benefits for attention to caffeine and L-theanine together. 30 14 15Human data
Tannins and other polyphenolspolyphenolsLeaf and stem
Not given.
Tea polyphenols lower iron absorption (radio-iron study, black and herb teas). 15 9Human data

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
Energy use (hypothesis)n/aThe Cochrane weight review states that catechins and caffeine are believed to increase energy metabolism; it found almost no weight change outside Japan. 12Hypothesis by reviewers
Liver injury from concentrated EGCGUGT1A4 and COMT variants (secondary trial analysis); an immune-related gene variant (NCCIH)Toxicology review: liver is the target organ in lab studies, tied to large single doses and fasting and to EGCG content. In a secondary trial analysis, women with the UGT1A4 A/C variant had larger ALT rises on high-dose extract. 8 2 25Lab and human
Caffeine plus L-theanine on attentionn/aCognitive benefits were seen with caffeine and L-theanine together and less with either alone. 14Human review
Iron absorptionn/aTea polyphenols reduce absorption of non-haem iron in a dose-related way (radio-iron study of black and herb teas). 9Human data

Absorption, metabolism and elimination

Absorption
Not covered in the sources read.
Distribution
Not covered.
Metabolism
A secondary trial analysis links the enzymes COMT and UGT1A4 with liver enzyme changes on high-dose extract.
Elimination
Not covered.
Bioavailability
Not covered.

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Isolated compounds versus whole extracts

Brewed tea, powdered whole leaf (matcha), liquid extracts and concentrated EGCG capsules are different products. EFSA estimates that supplements can deliver far more EGCG than infusions do; liver warnings come from the concentrated form. Hu and colleagues found liver events from concentrated preparations in large single doses, not from brewed tea. Trial results for extract cannot be applied to the drink, or the other way round.

Nutritional composition

Green tea is not a source of essential nutrients in the sources read. It contains caffeine, L-theanine, catechins and tannins.

8benefits and uses looked at
31studies and sources checked
Low certaintybest evidence rating found
6lab markers tracked in trials

5 low certainty1 very low certainty1 not enough evidence1 evidence against

What was looked at

The 8 benefits and uses checked for Green Tea, each with how strong the evidence is. Tap one to open it.

Lab markers tracked in the studies

LDL cholesterolSystolic blood pressureBody weightDeath from any causeHbA1cAttention and memory tests

What is Green Tea good for?

The uses people ask about and how strong the human evidence is for each. Most trials mix the drink with extracts, so none of these results is a clean answer about a cup of tea.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Cholesterol

Low certainty

Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain.

4 studiesMixed: drinks and extracts. Not a drink-only result.

Studies, doses and limits

What the trials found

A 2011 meta-analysis of 14 trials (1,136 people) of green tea drinks or extracts found a small fall in total and LDL cholesterol and no change in HDL. A Cochrane review of 7 green tea trials found larger falls that were not stable when checked. A 2020 review of 14 shorter trials of green or black tea (4 to 24 weeks) found no significant effect. NCCIH says most trials tested extract supplements, not the drink.

Results

Total cholesterol -7.20 mg/dL (95% CI -8.19 to -6.21) and LDL -2.19 mg/dL (-3.16 to -1.21) in the 2011 pooled trials; Cochrane green tea: total -0.62 mmol/L and LDL -0.64 mmol/L, not stable to sensitivity analysis; 2020 review: no significant change.

Effect sizes as reported

Small average falls; reviewers disagree on whether they are real in short trials.

Why this rating

Pooled drinks and extracts, small trials, results not stable, a later review found no effect.

Form and dose studied

Mixed: drinks and extracts. Not a drink-only result.

Who was studied

Healthy adults and adults at higher risk, mostly short trials.

Limits

Product types differ; most trials are short; no heart attack or stroke outcomes.

Why researchers looked

High LDL cholesterol is a risk factor for heart disease, and green tea catechins are often said to help.

Traditional use

Not described in the sources read.

Proposed mechanism Not established

No mechanism was established in the sources read.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

22 6 10 25

Blood pressure

Low certainty

Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect.

3 studiesGreen tea supplementation; the 2025 abstract does not separate drink …

Studies, doses and limits

What the trials found

A 2025 meta-analysis of 36 trials of green tea supplementation found average falls of about 1 mmHg in both systolic and diastolic pressure with very high differences between trials. The Cochrane review found larger falls (about 3 mmHg) from a small number of green tea trials that were not stable. A 2020 review of 14 trials of green or black tea (4 to 24 weeks) found no significant effect.

Results

Systolic -1.08 mmHg (95% CI -1.98 to -0.18), diastolic -1.09 mmHg (-1.67 to -0.50) in 36 trials; Cochrane green tea systolic -3.18 mmHg, diastolic -3.42 mmHg, unstable; 2020 review: no significant effect.

Effect sizes as reported

About 1 to 3 mmHg at most.

Why this rating

Very large differences between trials (I2 74 to 85 percent), unstable Cochrane result, one review with no effect.

Form and dose studied

Green tea supplementation; the 2025 abstract does not separate drink from extract.

Who was studied

Adults, with stronger effects in people who started with raised blood pressure.

Limits

Heterogeneity; mixed forms; small average change that may not matter to health.

Why researchers looked

High blood pressure is a leading risk factor for heart disease and stroke.

Traditional use

Not described in the sources read.

Proposed mechanism Not established

No mechanism was established in the sources read.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab. The authors call green tea a complementary approach, not a treatment for high blood pressure.

18 6 10

Body weight

Low certainty

A Cochrane review found almost no weight loss from green tea outside Japan. The Japanese trials were too different to combine and ranged from little change to a few kilograms.

2 studiesGreen tea preparations, drinks and extracts.

Studies, doses and limits

What the trials found

The review included trials of at least 12 weeks in overweight or obese adults: six outside Japan (532 people) and eight in Japan (1,030 people).

Results

Outside Japan: weight -0.04 kg (95% CI -0.5 to 0.4), BMI -0.2 kg/m2, waist -0.2 cm; none significant. Japanese trials ranged from -0.2 to -3.5 kg and could not be pooled.

Effect sizes as reported

No meaningful change outside Japan.

Why this rating

Short trials of 12 to 13 weeks, many preparation types, results differ by region.

Form and dose studied

Green tea preparations, drinks and extracts.

Who was studied

Overweight and obese adults.

Limits

Not a drink-only result; short.

Why researchers looked

Green tea contains catechins and caffeine, which reviewers say are believed to raise energy use.

Traditional use

NCCIH says green tea and extracts are promoted for weight loss.

Proposed mechanism Hypothesis

The Cochrane reviewers state a belief that catechins and caffeine may raise energy metabolism; they say the efficacy remains unclear.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

12 25

Cancer risk

Not enough evidence

A large Cochrane review found inconsistent, low-certainty results. It does not show that green tea prevents cancer.

2 studiesExtract in trials; drinking in observational studies.

Studies, doses and limits

What the trials found

The review used 142 studies: 11 trials of green tea extract (1,795 people) and 131 observational studies (over 1,100,000 people).

Results

Extract trials: prostate cancer RR 0.50 (95% CI 0.18 to 1.36), gynaecological RR 1.50 (0.41 to 5.48), skin RR 1.00 (0.06 to 15.92). Observational highest versus lowest intake: cancer incidence RR 0.83 (0.65 to 1.07); cancer death RR 0.99 (0.91 to 1.07). Results conflicted between study designs for some cancers.

Effect sizes as reported

Intervals include no effect.

Why this rating

Low-certainty and inconsistent results; mostly observational; Asian populations.

Form and dose studied

Extract in trials; drinking in observational studies.

Who was studied

Adults, mostly in Asia.

Limits

Cannot show cause; trials used extract.

Why researchers looked

Lab studies have suggested catechins may slow cancer cell growth; population studies have asked whether tea drinkers get less cancer.

Traditional use

Not described in the sources read.

Proposed mechanism Lab only

Cochrane notes that laboratory studies have suggested catechins may inhibit cancer cell growth. This is lab work and not shown in people.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

5 25

Heart disease and death rates in drinkers

Low certainty

In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it.

2 studiesGreen tea as a drink.

Studies, doses and limits

What the trials found

A pooled analysis of eight Japanese cohorts followed 313,381 people for a mean 17.3 years.

Results

Five or more cups a day versus less than one: all-cause death HR 0.90 (0.87 to 0.94) in men and 0.82 (0.74 to 0.90) in women; heart disease HR 0.82 and 0.75; stroke-type HR 0.76 and 0.78. In women only, total cancer death HR 0.89 (0.83 to 0.96) at 1 to 2 cups.

Effect sizes as reported

Roughly 10 to 18 percent lower all-cause death among the heaviest drinkers.

Why this rating

Observational; healthier lifestyle among drinkers cannot be ruled out; Japanese data.

Form and dose studied

Green tea as a drink.

Who was studied

Japanese adults.

Limits

Self-reported intake; cannot show cause; may not apply outside Japan.

Why researchers looked

Green tea is part of daily life in Japan, so large cohorts can compare heavy and light drinkers.

Traditional use

NCCIH notes that lower heart disease risk has been linked to green tea in Asian but not Western groups.

Proposed mechanism Not established

Not established. Observational data cannot identify a mechanism.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

1 25

Attention, memory and mood

Low certainty

A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together.

1 studiesGreen tea, green tea extract, L-theanine and EGCG.

Studies, doses and limits

What the trials found

Mancini 2017 reviewed 21 studies (4 randomised trials, 12 crossover studies, 4 cross-sectional studies, 1 cohort) on green tea, green tea extract, L-theanine and EGCG.

Results

The reviewers report evidence of less anxiety, better memory and attention and brain-scan changes with working memory. The abstract gives no numbers.

Effect sizes as reported

Not given in the abstract.

Why this rating

Mixed products (drink, extract, isolated L-theanine), many short or single-dose studies, no numbers in abstract.

Form and dose studied

Green tea, green tea extract, L-theanine and EGCG.

Who was studied

Mostly healthy adults.

Limits

Not a drink-only result; PubMed only; reviewers own quality scores.

Why researchers looked

Green tea contains caffeine and L-theanine, and people drink it for alertness with calm.

Traditional use

Not described in the sources read.

Proposed mechanism Human study observation

The reviewers say the effect cannot be put down to one ingredient: benefits for cognition appeared with caffeine and L-theanine together and were smaller with either alone.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

14

Dementia and memory loss risk

Very low certainty

Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason.

1 studiesGreen tea as a drink.

Studies, doses and limits

What the trials found

A 2019 systematic review found 3 cohort and 5 cross-sectional studies.

Results

One cohort and three cross-sectional studies supported a benefit, one cohort and one cross-sectional study partly supported it, and one of each found no link.

Effect sizes as reported

Not given in the abstract.

Why this rating

Eight observational studies, mixed results, cannot show cause.

Form and dose studied

Green tea as a drink.

Who was studied

Mostly Asian adults.

Limits

Observational; small number of studies.

Why researchers looked

Population studies in Asia asked whether regular green tea drinkers keep their memory longer.

Traditional use

Not described in the sources read.

Proposed mechanism Not established

Not established.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab.

13

Blood sugar in type 2 diabetes

Evidence against

A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes.

1 studiesGreen tea supplementation; type not stated in the abstract.

Studies, doses and limits

What the trials found

A 2021 meta-analysis pooled 14 randomised trials in people with type 2 diabetes.

Results

No significant effect on fasting glucose, fasting insulin, HbA1c or insulin resistance (HOMA-IR).

Effect sizes as reported

No significant effect.

Why this rating

One meta-analysis of 14 trials found no effect; the abstract does not give the product type; small trials, so no effect is not proof of none.

Form and dose studied

Green tea supplementation; type not stated in the abstract.

Who was studied

Adults with type 2 diabetes.

Limits

Small trials; form unclear.

Why researchers looked

Catechins have been proposed to affect blood sugar and insulin.

Traditional use

Not described in the sources read.

Proposed mechanism Not established

Not established in the source read.

A proposed mechanism does not show that the effect happens in people.

Brewed green tea has no safety concerns reported in adults (NCCIH) but contains caffeine. Concentrated extract capsules are a different product with rare serious liver injury reports. See the Safety tab. People taking diabetes medicines should speak to their prescriber before using any supplement.

3

Connections to the rest of health

How Green Tea connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

A. Wellness goals

Connected toKind of connectionEvidence statusContextStudies
Cholesterol Balance Low certainty Cholesterol: Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain. 22 6 10 25
Heart Health Low certainty Cholesterol: Pooled trials of green tea drinks and extracts show a small average fall in total and LDL cholesterol. Two reviews disagree, and most of the trial data comes from extract or mixed products, so the result for a cup of tea is uncertain. Blood pressure: Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect. 22 6 10 25 18
Blood Pressure Support Low certainty Blood pressure: Reviews find a very small average fall in blood pressure, with big differences between studies. One review of short trials found no effect. 18 6 10
Weight Management Low certainty Body weight: A Cochrane review found almost no weight loss from green tea outside Japan. The Japanese trials were too different to combine and ranged from little change to a few kilograms. 12 25
Preventive Wellness Not enough evidence Cancer risk: A large Cochrane review found inconsistent, low-certainty results. It does not show that green tea prevents cancer. 5 25
Heart Health Biological association Low certainty Heart disease and death rates in drinkers: In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it. 1 25
Longevity Biological association Low certainty Heart disease and death rates in drinkers: In Japan, people who drank five or more cups a day had somewhat lower death rates than people who drank less than one. This is an association and does not show tea caused it. 1 25
Mental Clarity Low certainty Attention, memory and mood: A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. 14
Better Focus Low certainty Attention, memory and mood: A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. 14
Memory Support Low certainty Attention, memory and mood: A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. 14
Brain Health Low certainty Attention, memory and mood: A systematic review found signs of better attention and memory and less anxiety, mostly in small or short studies. The effect seems to come from caffeine and L-theanine together. 14
Brain Health Biological association Very low certainty Dementia and memory loss risk: Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason. 13
Healthy Aging Biological association Very low certainty Dementia and memory loss risk: Observational studies lean towards lower risk in green tea drinkers, but they are few and mixed, and cannot show that tea is the reason. 13
Blood Sugar Balance Evidence against Blood sugar in type 2 diabetes: A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes. 3
Metabolic Health Evidence against Blood sugar in type 2 diabetes: A meta-analysis of 14 trials found no significant effect of green tea supplements on blood sugar measures in people with type 2 diabetes. 3

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Cardiovascular System Biological association Low certainty Studied for: Cholesterol Studied for: Blood pressure 22 6 10 25 18 1
Metabolism Weight Biological association Low certainty Studied for: Body weight Studied for: Blood sugar in type 2 diabetes 12 25 3
Cellular Biological association Not enough evidence Studied for: Cancer risk 5 25
Brain Focus Biological association Low certainty Studied for: Attention, memory and mood Studied for: Dementia and memory loss risk 14 13

C. Body parts and organs

Connected toKind of connectionEvidence statusContextStudies
Liver Adverse effect or risk Low certainty Rare liver injury, mostly with extract; case reports and trials of high-dose EGCG.
Preparation or compound: Concentrated green tea extract; rarely tea
16 4 17

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
Pregnancy Contraindication Low certainty Counts toward the caffeine limit.
Preparation or compound: Green tea (caffeine)
26 25
Iron-deficiency anemia Adverse effect or risk Very low certainty Tea can lower iron absorption; one case report.
Preparation or compound: Green tea drink
9 7

I. Biomarkers

Connected toKind of connectionEvidence statusContextStudies
LDL cholesterol Biological association Low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 22 10 6
Systolic blood pressure Biological association Low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 18 10 6
Body weight Biological association Low certainty Measured in trials: unchanged. A lab change is not the same as a health benefit. 12
Death from any cause Biological association Low certainty Measured in trials: lowered. A lab change is not the same as a health benefit. 1
HbA1c Biological association Evidence against Measured in trials: unchanged. A lab change is not the same as a health benefit. 3
Attention and memory tests Biological association Low certainty Measured in trials: raised. A lab change is not the same as a health benefit. 14

J. Genes, receptors and enzymes

Connected toKind of connectionEvidence statusContextStudies
UGT1A4 Preliminary mechanism Human Genotype linked with liver enzyme rises on high-dose extract in one secondary analysis. 2
COMT Preliminary mechanism Human Genotype examined with liver enzyme changes on high-dose extract. 2

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
Caffeine Adverse effect or risk Moderate certainty Counts toward daily caffeine; see FDA and NHS figures.
Preparation or compound: Green tea
24 26
Epigallocatechin gallate (EGCG) Biological association Human Liver effects at high supplement doses; other actions not established in the sources read.
Preparation or compound: Leaf
28 4 20
Caffeine Biological association Human Stimulant; see Safety tab.
Preparation or compound: Leaf
29 24
L-theanine Biological association Human Reviewers link benefits for attention to caffeine and L-theanine together.
Preparation or compound: Leaf
30 14 15
Tannins and other polyphenols Biological association Human Tea polyphenols lower iron absorption (radio-iron study, black and herb teas).
Preparation or compound: Leaf and stem
15 9

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).

Evidence at a glance: what changed in 4 lab markers

Tap a number to show only those markers. Counts are markers, not people.

The evidence

The research centre for Green Tea. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We searched PubMed and read the abstracts of about 22 sources, read the NCCIH, FDA, NHS and EMA pages and the IARC press release, checked the plant name in GBIF and three compounds in PubChem, and looked for LiverTox and LactMed (summary records read; the full LiverTox page was not opened). Only abstracts were read for papers. Certainty ratings are the compiler's own reading. No funding statement was read for most papers, so industry links are not ruled out. No study is cited that we could not verify.

Study library: every study we checked 31
StudyDesignPeopleProduct, dose, lengthResult
Abe 2019
Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan
European Journal of Epidemiology · PMID 31392470 · DOI
Pooled cohort
313381
313,381 Japanese adults in eight cohorts; 52,943 deaths over a mean 17.3 years
Green tea drinking (self-reported)
leaf (drink) Five or more cups a day versus less than one Mean follow-up 17.3 years · vs Drinking less than 1 cup a day
Five or more cups a day versus less than one: all-cause death HR 0.90 (95% CI 0.87 to 0.94) in men and 0.82 (0.74 to 0.90) in women; heart disease HR 0.82 (0.75 to 0.90) men, 0.75 (0.68 to 0.84) women; stroke-type (cerebrovascular) HR 0.76 (0.68 to 0.85) men, 0.78 (0.68 to 0.89) women. In women, total cancer death HR 0.89 (0.83 to 0.96) at 1 to 2 cups and 0.91 (0.85 to 0.98) at 3 to 4 cups.
Lower death rates among heavy green tea drinkers (an association) (All-cause HR 0.90 (0.87, 0.94) men; 0.82 (0.74, 0.90) women)
Methods, limits and funding

Outcomes: Deaths from all causes, heart disease, stroke, cancer, respiratory disease

Limitations: Observational: tea drinkers may differ in diet, exercise and health; Japanese data may not apply elsewhere

Funding and conflicts: Not stated in the abstract

Read: abstract

Acosta 2023
Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5-Diphospho-glucuronosyltransferase 1A4 Genotypes
Journal of Dietary Supplements · PMID 36178169 · DOI
Controlled trial
1075
Postmenopausal women in the Minnesota Green Tea Trial (400 in the extract group), mean age 59.8 years
High-dose green tea extract capsules (843 mg/day EGCG) versus placebo capsules
extract 843 mg/day EGCG 12 months · vs Placebo capsules
This is a secondary analysis. In the extract group, women with the UGT1A4 (rs6755571) A/C variant had larger rises in ALT (about +78% and +82% at months 6 and 9) than women with C/C (about +28% and +30%). The authors suggest this variant may be a risk factor for meaningful liver enzyme rises with 6 to 9 months of high-dose extract.
Genes may affect who gets liver enzyme rises on high-dose extract (ALT change differences p<0.001 and p=0.004 (months 6 and 9))
Methods, limits and funding

Outcomes: Liver enzymes by gene variant

Limitations: Secondary analysis; mostly white women; extract only; not about tea

Funding and conflicts: Not stated in the abstract

Read: abstract

Asbaghi 2021
Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
Diabetes & Metabolic Syndrome · PMID 33285391 · DOI
Meta-analysis
14 randomised trials in people with type 2 diabetes Green tea supplementary intake
Differed Differed · vs Control
Supplementary green tea had no significant effect on fasting glucose, fasting insulin, HbA1c or HOMA-IR.
No significant effect found
Methods, limits and funding

Outcomes: Fasting glucose, fasting insulin, HbA1c, HOMA-IR

Limitations: Small trials; the abstract does not say whether the trials used drink or extract; no effect found is not proof of no effect

Funding and conflicts: Not stated in the abstract

Read: abstract

EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) 2018
Scientific opinion on the safety of green tea catechins
EFSA Journal · PMID 32625874 · DOI
Regulatory opinion
Review of published studies, authority reports and submitted data Green tea infusions, reconstituted drinks and food supplements containing catechins
leaf (drink) and extract Mean EGCG intake from infusions in the EU 90 to 300 mg/day (up to 866 mg/day for high-level drinkers); supplements 5 to 1,000 mg/day
Catechins from traditionally prepared green tea infusions, and reconstituted drinks of the same composition, are in general considered safe at the intakes reported in EU countries. Rare cases of liver injury have been reported after infusions, most probably an idiosyncratic (individual) reaction. Clinical trials show that EGCG at or above 800 mg a day taken as a food supplement raised liver enzymes (serum transaminases) compared with control.
Drink generally safe at usual intakes; high-dose supplements raise liver enzymes
Methods, limits and funding

Outcomes: Liver safety of catechins (EGCG)

Limitations: Abstract only was read; the full opinion could not be opened

Funding and conflicts: Regulator opinion

Read: abstract

Filippini 2020
Green tea (Camellia sinensis) for the prevention of cancer
Cochrane Database of Systematic Reviews · PMID 32118296 · DOI
Systematic review
142 studies: 11 randomised trials (1795 people, green tea extract versus placebo) and 131 observational studies (over 1,100,000 people) Green tea extract in trials; drinking green tea in observational studies
leaf (drink) and extract Differed Differed · vs Placebo (trials); lowest intake (cohorts)
Trials of extract (low-certainty): prostate cancer RR 0.50 (95% CI 0.18 to 1.36), gynaecological cancer RR 1.50 (0.41 to 5.48), non-melanoma skin cancer RR 1.00 (0.06 to 15.92). Observational, highest versus lowest intake: overall cancer incidence RR 0.83 (0.65 to 1.07, three studies); cancer death RR 0.99 (0.91 to 1.07, eight studies); both low-certainty. Results conflicted by study design for oesophageal, prostate and urinary cancers and leukaemia. The authors call the evidence limited and inconsistent. Extract side effects included stomach and gut problems, raised liver enzymes and, more rarely, insomnia, raised blood pressure and skin reactions.
No clear effect on cancer risk; inconsistent (Prostate RR 0.50 (0.18, 1.36); cancer incidence RR 0.83 (0.65, 1.07); cancer mortality RR 0.99 (0.91, 1.07))
Methods, limits and funding

Outcomes: Cancer incidence and death, adverse effects, quality of life

Limitations: Most studies in Asian populations who drink a lot of green tea; observational studies cannot prove cause; trials used extract

Funding and conflicts: Non-US government support listed in PubMed record

Read: abstract

Hartley 2013
Green and black tea for the primary prevention of cardiovascular disease
Cochrane Database of Systematic Reviews · PMID 23780706 · DOI
Systematic review
821
11 randomised trials of at least 3 months in healthy adults or adults at high risk of heart disease; 7 trials tested green tea, 4 black tea
Green tea, black tea or tea extracts (doses and forms differed between trials)
leaf (drink) and extracts Differed between trials At least 3 months · vs No intervention, placebo or minimal intervention
No trial reported heart or blood vessel events. Green tea: total cholesterol -0.62 mmol/L (95% CI -0.77 to -0.46), LDL cholesterol -0.64 mmol/L (-0.77 to -0.52), systolic blood pressure -3.18 mmHg (-5.25 to -1.11), diastolic -3.42 (-4.54 to -2.30). The authors say only a small number of studies contributed and the green tea results were not stable to sensitivity analysis. Adverse events in five trials were judged unlikely to be due to the tea.
Small lowering of cholesterol and blood pressure, unstable (TC MD -0.62 (-0.77, -0.46); LDL MD -0.64 (-0.77, -0.52); SBP MD -3.18 (-5.25, -1.11))
Methods, limits and funding

Outcomes: Heart disease events, blood pressure, cholesterol

Limitations: Few trials per analysis, risk of bias, forms and doses mixed (drink and extract); no long-term follow-up

Funding and conflicts: Non-US government support listed in PubMed record; no industry funding stated in the abstract

Read: abstract

He 2024
Severe iron-deficiency anemia after short-term moderate consumption of green tea in woman: A rare case report
Heliyon · PMID 39263133 · DOI
Case report
1
One woman who drank moderate amounts of green tea for about three months
Green tea drink
leaf (drink) Moderate (amount not given in the abstract) About 3 months
Haemoglobin fell by 6.9 g/dl with severe iron-deficiency anemia. After she changed her tea habits there was no recurrence. The authors say clinicians should know even moderate tea intake can cause severe anemia in people who are especially vulnerable to its effect on iron absorption.
One reported case of severe anemia
Methods, limits and funding

Outcomes: Haemoglobin

Limitations: Single case; other causes of iron loss are not described in the abstract

Funding and conflicts: Not stated

Read: abstract

Hu 2018
The safety of green tea and green tea extract consumption in adults - Results of a systematic review
Regulatory Toxicology and Pharmacology · PMID 29580974 · DOI
Systematic review
Toxicology studies and adverse-event data from 159 human intervention studies Brewed green tea, green tea in drinks or food, and concentrated catechin-rich preparations
leaf (drink) and extract
Liver was the target organ. Liver adverse events in humans came from a limited range of concentrated, catechin-rich preparations taken as large single doses, and not from brewed tea or extracts used in drinks or food. The authors derived a safe intake level for adults for solid single-dose preparations and a separate, higher observed safe level for beverage forms (the numbers are in the paper).
Liver effects tied to concentrated bolus-dose preparations, not brewed tea
Methods, limits and funding

Outcomes: Liver adverse events

Limitations: Abstract only was read; the abstract does not state who funded the review

Funding and conflicts: Funding and conflict-of-interest statement not read

Read: abstract

Hurrell 1999
Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages
British Journal of Nutrition · PMID 10999016
Controlled trial
Adult volunteers given a bread meal with radio-labelled iron Black tea, herb teas (chamomile, vervain, lime flower, pennyroyal, peppermint), coffee and cocoa
leaf (drink) Test beverages with different polyphenol amounts Single meals · vs Water control meal
All the beverages reduced iron absorption in a way that depended on their polyphenol content. Black tea cut absorption by 79 to 94 percent, peppermint tea 84, pennyroyal 73, cocoa 71, vervain 59, lime flower 52 and camomile 47 percent. Milk made little difference. Green tea was NOT tested.
Large drop in iron absorption from a meal
Methods, limits and funding

Outcomes: Iron absorption from the meal

Limitations: Green tea not tested; single meals in adults; applying this to green tea is an inference

Funding and conflicts: Non-US government support listed in PubMed record

Read: abstract

Igho-Osagie 2020
Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Journal of Nutrition · PMID 33188386 · DOI
Meta-analysis
798
14 randomised trials in healthy adults and at-risk adults (obesity, prediabetes, borderline high cholesterol, metabolic syndrome)
Green tea or black tea
leaf (drink) Differed 4 to 24 weeks (mean 7.4) · vs Placebo or control
No significant effect of tea on systolic or diastolic blood pressure, total, LDL or HDL cholesterol or triglycerides. Strength of evidence was low to moderate because the studies were small and underpowered.
No significant effect in short trials (No significant effects (intervals not given in the abstract))
Methods, limits and funding

Outcomes: Blood pressure, total, LDL and HDL cholesterol, triglycerides

Limitations: Small trials, short duration, green and black tea pooled; absence of effect is not proof of no effect

Funding and conflicts: Non-US government support listed in PubMed record

Read: abstract

Jayasingha 2025
Fluoride in tea: accumulation, dietary exposure, and future strategies for risk mitigation in food safety; a scoping review
Critical Reviews in Food Science and Nutrition · PMID 40504749 · DOI
Scoping review
lab/food analysis
88 studies worldwide on fluoride in tea Tea (all types)
leaf (drink)
Tea plants take up fluoride from soil. Longer brewing released more fluoride. Average levels by type were brick tea 4.78 mg/L, black tea 2.73, green tea 1.37, white tea 0.49 and herbal tea 0.17. The review says black tea poses risks for children and for adults in high-intake regions; excessive intake may cause tooth and bone fluorosis and kidney disease.
Green tea has less fluoride than black or brick tea but more than white or herbal tea
Methods, limits and funding

Outcomes: Fluoride in brewed tea

Limitations: Scoping review; averages mix many countries; local water also adds fluoride

Funding and conflicts: Not stated

Read: abstract

Jurgens 2012
Green tea for weight loss and weight maintenance in overweight or obese adults
Cochrane Database of Systematic Reviews · PMID 23235664 · DOI
Systematic review
Randomised trials of at least 12 weeks in overweight or obese adults; six trials outside Japan (532 people) and eight in Japan (1030 people) Green tea preparations (drink and extracts)
leaf (drink) and extracts Differed 12 to 13 weeks · vs Control
Outside Japan: weight difference -0.04 kg (95% CI -0.5 to 0.4), BMI -0.2 kg/m2 (-0.5 to 0.1), waist -0.2 cm (-1.4 to 0.9). The eight Japanese trials were too different to pool; weight differences ranged from -0.2 to -3.5 kg. Adverse events in four of eight trials that recorded them were mild to moderate; two needing hospital care were reported as not related.
Almost no weight change outside Japan; mixed results in Japanese trials (Weight MD -0.04 kg (-0.5, 0.4) outside Japan)
Methods, limits and funding

Outcomes: Weight, BMI, waist circumference, adverse events

Limitations: Short trials; green tea preparations of many kinds; not a drink-only result

Funding and conflicts: Non-US government support listed in PubMed record

Read: abstract

Kakutani 2019
Green Tea Intake and Risks for Dementia, Alzheimer's Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review
Nutrients · PMID 31137655 · DOI
Systematic review
3 cohort studies and 5 cross-sectional studies Green tea drinking
leaf (drink) · vs Lower or no intake
One cohort and three cross-sectional studies supported a benefit, one cohort and one cross-sectional partly supported it, and one cohort and one cross-sectional found no association. The authors say well-designed cohort studies are needed.
Mixed observational results
Methods, limits and funding

Outcomes: Dementia, Alzheimer disease, mild cognitive impairment, cognitive impairment

Limitations: Observational only; small number of studies; cannot show cause

Funding and conflicts: Not stated in the abstract

Read: abstract

Mancini 2017
Green tea effects on cognition, mood and human brain function: A systematic review
Phytomedicine · PMID 28899506 · DOI
Systematic review
21 studies: 4 randomised trials, 12 crossover studies, 4 cross-sectional studies and 1 cohort Green tea, green tea extract, L-theanine or EGCG
leaf (drink), extract and isolated compounds Differed Differed · vs Differed
The reviewers found evidence that green tea influences psychological symptoms (for example less anxiety), cognition (for example memory and attention) and brain function (for example working-memory activation on brain scans). Benefits on cognition were seen with caffeine and L-theanine together, with less effect from either alone, so the effect cannot be put down to one ingredient.
Possible small effects on attention and memory
Methods, limits and funding

Outcomes: Anxiety and mood, memory and attention, brain activity

Limitations: Mixes drink, extract and isolated compounds; many short or single-dose studies; PubMed only; quality scores are the reviewers own

Funding and conflicts: Not stated in the abstract

Read: abstract

NICHD / 2006
Drugs and Lactation Database (LactMed): Green Tea
LactMed (NCBI Bookshelf) · PMID 30000907
Database record
n/a Green tea leaves and stems
leaf and stem
Green tea leaves and stems contain caffeine, L-theanine, polyphenols and tannins. Fussiness, jitteriness and poor sleep have been reported in infants of mothers with extremely high caffeine intakes. Giving tea directly to infants can interfere with iron absorption and cause anemia, but anemia in breastfed infants has not been reported with maternal tea intake. Passage of L-theanine into breastmilk has not been studied. No studies of oral green tea extract in breastfeeding were found.
No clear harm from usual maternal tea intake; caution at very high caffeine
Methods, limits and funding

Outcomes: Breastfeeding safety

Limitations: Summary record; no new data

Funding and conflicts: Public database

Read: abstract

NIDDK 2012
LiverTox: Green Tea (Clinical and Research Information on Drug-Induced Liver Injury)
LiverTox (NCBI Bookshelf) · PMID 31643260
Database record
n/a Green tea extract and, more rarely, large amounts of green tea
leaf and extract
Green tea extract and, more rarely, ingestion of large amounts of green tea have been implicated in cases of clinically apparent acute liver injury, including instances of acute liver failure and either need for urgent liver transplantation or death.
Rare but serious liver injury, mostly with extract
Methods, limits and funding

Outcomes: Drug-induced liver injury

Limitations: Only the PubMed summary was read; the full LiverTox page was not opened

Funding and conflicts: Public database

Read: abstract

Pillukat 2014
Concentrated green tea extract induces severe acute hepatitis in a 63-year-old woman - a case report with pharmaceutical analysis
Journal of Ethnopharmacology · PMID 24862489 · DOI
Case report
1
A 63-year-old woman taking green tea capsules on the advice of a cancer support group
Concentrated green tea extract capsules (EGCG 93.2% of the catechins found)
extract Very high EGCG dose level per the analysis
Severe hepatitis assessed as probably caused by the capsules (CIOMS/RUCAM score). The liver tissue pattern fit drug-induced hepatitis and other causes were excluded. After stopping, and a treatment called albumin dialysis, she recovered quickly and fully. Lab analysis of the capsules found no contaminants.
Severe but reversible liver injury linked to concentrated extract
Methods, limits and funding

Outcomes: Liver injury

Limitations: Single case; extract, not brewed tea

Funding and conflicts: Not stated

Read: abstract

Rezaei 2025
Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials
Blood Pressure · PMID 40497293 · DOI
Meta-analysis
36 randomised trials in adults Green tea supplementation (forms not broken out in the abstract)
Not given here Studies of 8 weeks or less showed stronger effects · vs Control or placebo
Systolic blood pressure fell by 1.08 mmHg (95% CI -1.98 to -0.18; I2 85%) and diastolic by 1.09 mmHg (-1.67 to -0.50; I2 74%). Effects were stronger in people with raised starting blood pressure, shorter studies, Asian populations and women. No clear link between size of change and dose or duration. The authors call green tea a complementary approach, not a treatment.
Very small average blood pressure drop with large differences between studies (SBP -1.08 (-1.98, -0.18); DBP -1.09 (-1.67, -0.50))
Methods, limits and funding

Outcomes: Systolic and diastolic blood pressure

Limitations: Very high heterogeneity; the abstract does not separate drink from extract; the GRADE rating is not given in the abstract

Funding and conflicts: Not stated in the abstract

Read: abstract

Rodriguez 2020
Human exposure to fluoride from tea (Camellia sinensis) in a volcanic region - Canary Islands, Spain
Environmental Science and Pollution Research · PMID 32740848 · DOI
Food analysis
lab/food analysis
90
90 tea samples (Canary Islands)
Mixed, black and other teas prepared with local tap water
leaf (drink) Two 250 mL cups a day assumed
Mixed teas (2.82 mg/L) and black teas (2.28 mg/L) had the highest fluoride. Two daily cups of those teas made with local tap water would give children aged 4 to 8 a large share (74.4% and 63.6%) of the EFSA upper intake level. The authors advise less tea for children and in pregnancy.
Fluoride in tea can matter for young children in some regions
Methods, limits and funding

Outcomes: Fluoride in tea

Limitations: Local water and region; green tea results are not given in the abstract

Funding and conflicts: Not stated

Read: abstract

Saklar 2015
Effects of different brewing conditions on catechin content and sensory acceptance in Turkish green tea infusions
Journal of Food Science and Technology · PMID 26396411 · DOI
Lab analysis
lab/food analysis
Turkish green tea brewed at 75, 85 and 95 C for 1 to 45 minutes; nine trained tasters Brewed Turkish green tea
leaf (drink)
Brewing at 85 C for 3 minutes gave the most EGCG (50.69 mg per 100 ml) with the best taste scores. Brewing 30 and 45 minutes at 85 and 95 C tasted bitter and dark.
Catechin level and taste depend on brewing time and heat
Methods, limits and funding

Outcomes: Catechin content and taste

Limitations: One tea, a laboratory study with nine tasters; not a rule for all green teas

Funding and conflicts: Not stated

Read: abstract

Taylor 1999
Probable antagonism of warfarin by green tea
Annals of Pharmacotherapy · PMID 10332534 · DOI
Case report
1
A 44-year-old man with a mechanical aortic heart valve taking warfarin
Green tea drink
leaf (drink) Half a gallon to a gallon of green tea a day for about a week About 1 week before the low reading
The INR fell from 3.79 to 1.37 about three weeks later, and was 1.14 a month after. He had started drinking one-half to one gallon of green tea a day about a week before the INR of 1.37. After stopping the tea the INR rose to 2.55. The authors suggested vitamin K in the tea.
A drop in warfarin effect linked in time to a very large amount of green tea (INR 3.79 to 1.37)
Methods, limits and funding

Outcomes: Blood clotting test (INR)

Limitations: One case; cannot prove cause; very large amount of tea; vitamin K content was not measured

Funding and conflicts: Not stated

Read: abstract

Zheng 2011
Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials
American Journal of Clinical Nutrition · PMID 21715508 · DOI
Meta-analysis
1136
14 randomised trials in adults
Green tea beverage or green tea extract
leaf (drink) and extract Differed Differed · vs Control
Total cholesterol lowered by 7.20 mg/dL (95% CI -8.19 to -6.21) and LDL cholesterol by 2.19 mg/dL (-3.16 to -1.21); HDL cholesterol did not change significantly. The authors say changes were not influenced by type of intervention, dose, duration, health status or study quality.
Small average drop in total and LDL cholesterol (TC -7.20 (-8.19, -6.21) mg/dL; LDL -2.19 (-3.16, -1.21) mg/dL)
Methods, limits and funding

Outcomes: Total, LDL and HDL cholesterol

Limitations: Mixes drinks and extracts; the abstract gives no separate drink-only result; later reviews found no effect in short trials (see Igho-Osagie 2020)

Funding and conflicts: Non-US government support listed in PubMed record; funding details not in the abstract

Read: abstract

n/a 2016
IARC (WHO): Press release no. 244, coffee, mate and very hot beverages (15 June 2016)
n/a · Source
Authoritative guidance
n/a
n/a n/a
IARC classified drinking very hot beverages as probably carcinogenic to humans (Group 2A), based on limited evidence from studies in places where tea or mate is drunk very hot, and said it is the temperature rather than the drink that appears responsible.
Methods, limits and funding

Outcomes: IARC classified drinking very hot beverages as probably carcinogenic to humans (Group 2A), based on limited evidence from studies in places where tea or mate is drunk very hot, and said it is the temperature rather than the drink that appears responsible.

Limitations: Press release read from the PDF on 2026-10-25; the exact temperature figure could not be read from the extracted text, so it is not quoted here.

Read: full-text

n/a 2024
FDA: Spilling the Beans: How Much Caffeine Is Too Much? (content current as of 28 Aug 2024)
n/a · Source
Authoritative guidance
n/a
n/a n/a
Lists green tea at 37 mg caffeine per 12 fl oz drink. Cites 400 mg a day as an amount not generally linked with negative effects in most adults, with wide differences in sensitivity. Lists signs of too much caffeine (faster heart rate, palpitations, high blood pressure, insomnia, anxiety, jitters, upset stomach, nausea, headache). Says caffeinated drinks should be avoided for children younger than age 2 (quoting the Dietary Guidelines) and that pregnant or breastfeeding people should talk to a health professional.
Methods, limits and funding

Outcomes: Lists green tea at 37 mg caffeine per 12 fl oz drink. Cites 400 mg a day as an amount not generally linked with negative effects in most adults, with wide differences in sensitivity. Lists signs of too much caffeine (faster heart rate, palpitations, high blood pressure, insomnia, anxiety, jitters, upset stomach, nausea, headache). Says caffeinated drinks should be avoided for children younger than age 2 (quoting the Dietary Guidelines) and that pregnant or breastfeeding people should talk to a health professional.

Limitations: Consumer guidance page, not a trial. Read in full on 2026-10-25.

Read: full-text

n/a 2025
NCCIH (NIH): Green Tea: Usefulness and Safety (last updated February 2025)
n/a · Source
Authoritative guidance
n/a
n/a n/a
Says definite conclusions cannot yet be reached on whether green tea helps for most uses. Cancer results inconsistent; lower heart disease risk seen in Asian but not Western groups; small cholesterol drops mostly from extract trials; no safety concerns reported for green tea as a drink in adults; liver injury uncommon and mostly with extract tablets or capsules; interactions with nadolol (high-dose green tea), atorvastatin (extract) and raloxifene; keep caffeine moderate in pregnancy.
Methods, limits and funding

Outcomes: Says definite conclusions cannot yet be reached on whether green tea helps for most uses. Cancer results inconsistent; lower heart disease risk seen in Asian but not Western groups; small cholesterol drops mostly from extract trials; no safety concerns reported for green tea as a drink in adults; liver injury uncommon and mostly with extract tablets or capsules; interactions with nadolol (high-dose green tea), atorvastatin (extract) and raloxifene; keep caffeine moderate in pregnancy.

Limitations: A regulator-style fact sheet, not a trial. Page text read in full on 2026-10-25.

Read: full-text

n/a 2026
NHS (UK): Foods to avoid in pregnancy (page last reviewed 15 June 2026)
n/a · Source
Authoritative guidance
n/a
n/a n/a
Says you should not have more than 200 mg of caffeine a day in pregnancy, estimates about 75 mg in a cup of tea such as black or green tea, and says too much caffeine has been linked to a higher chance of miscarriage and stillbirth.
Methods, limits and funding

Outcomes: Says you should not have more than 200 mg of caffeine a day in pregnancy, estimates about 75 mg in a cup of tea such as black or green tea, and says too much caffeine has been linked to a higher chance of miscarriage and stillbirth.

Limitations: Public-health guidance, not a trial. Read in full on 2026-10-25. The per-cup figure is an estimate.

Read: full-text

n/a 2026
EMA: Camelliae sinensis non fermentatum folium (green tea), herbal medicinal product page
n/a · Source
Authoritative guidance
n/a
n/a n/a
Page lists Camellia sinensis (L.) Kuntze, non fermentatum folium (green tea), therapeutic area "Fatigue and weakness", status "Assessment finalised", outcome "European Union herbal monograph". Documents: final EU herbal monograph (EMA/HMPC/283630/2012, published 29 April 2014), assessment report and an addendum to the assessment report (EMA/HMPC/30571/2022, published 26 September 2022).
Methods, limits and funding

Outcomes: Page lists Camellia sinensis (L.) Kuntze, non fermentatum folium (green tea), therapeutic area "Fatigue and weakness", status "Assessment finalised", outcome "European Union herbal monograph". Documents: final EU herbal monograph (EMA/HMPC/283630/2012, published 29 April 2014), assessment report and an addendum to the assessment report (EMA/HMPC/30571/2022, published 26 September 2022).

Limitations: Only the web page was read. The monograph and assessment-report PDFs were not opened, so the wording of the monograph is NOT verified.

Read: abstract

n/a 2026
PubChem: epigallocatechin gallate (CID 65064), formula C22H18O11
n/a · Source
Database record
n/a
n/a n/a
Compound record confirmed through the PubChem API on 2026-10-25.
Methods, limits and funding

Outcomes: Compound record confirmed through the PubChem API on 2026-10-25.

Limitations: Database record only.

Read: full-text

n/a 2026
PubChem: caffeine (CID 2519), formula C8H10N4O2
n/a · Source
Database record
n/a
n/a n/a
Compound record confirmed through the PubChem API on 2026-10-25.
Methods, limits and funding

Outcomes: Compound record confirmed through the PubChem API on 2026-10-25.

Limitations: Database record only.

Read: full-text

n/a 2026
PubChem: L-theanine (CID 439378), formula C7H14N2O3
n/a · Source
Database record
n/a
n/a n/a
Compound record confirmed through the PubChem API on 2026-10-25.
Methods, limits and funding

Outcomes: Compound record confirmed through the PubChem API on 2026-10-25.

Limitations: Database record only.

Read: full-text

n/a 2026
GBIF Backbone Taxonomy: Camellia sinensis (L.) Kuntze (usage key 3189635), retrieved 2026-10-25
n/a · Source
Database record
n/a
n/a n/a
Accepted species, family Theaceae, order Ericales, genus Camellia. Synonyms listed by the API include Camellia bohea (L.) Sweet, Camellia chinensis (Sims) Kuntze and Camellia cantonensis Lour.
Methods, limits and funding

Outcomes: Accepted species, family Theaceae, order Ericales, genus Camellia. Synonyms listed by the API include Camellia bohea (L.) Sweet, Camellia chinensis (Sims) Kuntze and Camellia cantonensis Lour.

Limitations: Taxonomic database record via the GBIF API.

Read: full-text

What we do not know yet

  • What the evidence supports: low-certainty small effects on cholesterol and blood pressure; no clear effect on weight, cancer or blood sugar.
  • No long-term trial of green tea as a drink (not extract) with heart attack, stroke or death as outcomes.
  • Most trials mix drinks and extracts, so results cannot be assigned to a cup of tea.
  • Most population data come from Japan and China; results may not apply elsewhere.
  • No measured lead, cadmium, aluminium or pesticide values for green tea were found; the EMA monograph and LiverTox full text were not opened; Health Canada caffeine page did not load.

How new research is added

New studies are found by a saved PubMed search and are placed in a review queue. A person reads each one before it changes any evidence rating or safety wording. New publications never change ratings automatically.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Metabolic 3

▼

LDL cholesterol

Lowered in trials

The cholesterol carried in the blood that is linked with higher heart disease risk.

Low certainty
Results and what it means

Why it was measured

To see whether green tea changes blood fats.

Statistical vs. clinical meaning

Small and inconsistent; a lab number, not a heart outcome.

Safety implication

None from the numbers; see the Safety tab for extract risks.

StudyResultPeopleProduct
22LDL -2.19 mg/dL (95% CI -3.16 to -1.21)Adults in 14 trialsGreen tea drinks or extracts
10No significant change in LDL798 people in 14 trialsGreen or black tea, 4 to 24 weeks

22 10 6

●

Body weight

Unchanged in trials

Weight in kilograms.

Low certainty
Results and what it means

Why it was measured

To see whether green tea helps with weight loss.

Statistical vs. clinical meaning

No meaningful change outside Japan.

Safety implication

None.

StudyResultPeopleProduct
12-0.04 kg (95% CI -0.5 to 0.4) outside Japan; -0.2 to -3.5 kg in Japanese trials, not pooledOverweight adults, 12 to 13 weeksGreen tea preparations

12

●

HbA1c

Unchanged in trials

A blood test that shows average blood sugar over about three months.

Evidence against
Results and what it means

Why it was measured

To see whether green tea helps people with type 2 diabetes.

Statistical vs. clinical meaning

No effect found.

Safety implication

None.

StudyResultPeopleProduct
3No significant effect on HbA1c, fasting glucose, insulin or HOMA-IR14 trials in type 2 diabetesGreen tea supplementation

3

Other 3

▼

Systolic blood pressure

Lowered in trials

The top number in a blood pressure reading.

Low certainty
Results and what it means

Why it was measured

To see whether green tea changes blood pressure.

Statistical vs. clinical meaning

Very small and varied.

Safety implication

None from the numbers.

StudyResultPeopleProduct
18-1.08 mmHg (95% CI -1.98 to -0.18)36 trials in adultsGreen tea supplementation
10No significant change798 people in 14 trialsGreen or black tea, 4 to 24 weeks

18 10 6

▼

Death from any cause

Lowered in trials

The risk of dying from any cause during follow-up.

Low certainty
Results and what it means

Why it was measured

To see whether heavy green tea drinkers live longer.

Statistical vs. clinical meaning

Observational association only.

Safety implication

None.

StudyResultPeopleProduct
1HR 0.90 (0.87 to 0.94) men; 0.82 (0.74 to 0.90) women, 5+ cups a day versus under 1313,381 Japanese adultsSelf-reported green tea drinking

1

▲

Attention and memory tests

Raised in trials

Scores on computer or paper tests of attention and working memory.

Low certainty
Results and what it means

Why it was measured

To see whether green tea affects thinking.

Statistical vs. clinical meaning

Possible small effect.

Safety implication

None.

StudyResultPeopleProduct
14Reviewers report better memory and attention with caffeine and L-theanine together; no numbers in the abstract21 mixed studiesGreen tea, extract, L-theanine, EGCG

14

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 7
  • A cup of tea and a green tea extract capsule are not the same thing. NCCIH reports no safety concerns for green tea drunk as a beverage by adults, apart from its caffeine. Liver injury is uncommon but has been reported, mostly with concentrated extract in tablets or capsules. EFSA judged traditionally prepared green tea infusions generally safe at the intakes seen in Europe, and found that high-dose EGCG supplements raised liver enzymes in trials. Do not carry safety or benefit results from one form to the other. Authoritative guidance 25 4 8
  • Rare liver injury, mostly with extract. LiverTox says green tea extract, and more rarely large amounts of green tea, have been linked to clinically apparent liver injury, including liver failure needing transplant or ending in death. EFSA noted rare cases after infusions too, probably an individual reaction. A case report describes severe hepatitis from concentrated extract capsules that cleared after stopping them. Anyone with liver disease, or who has had liver trouble from a supplement, should ask a clinician before any extract. Case report 16 4 17
  • Caffeine. Green tea contains caffeine. The FDA lists 37 mg in a 12 fl oz drink and says about 400 mg a day is not generally linked with harm in most adults, with wide differences in sensitivity. Too much can cause fast heartbeat, palpitations, high blood pressure, poor sleep, anxiety, jitters, upset stomach, nausea and headache. Authoritative guidance 24
  • Pregnancy, breastfeeding and young children. The NHS says not to have more than 200 mg of caffeine a day in pregnancy and counts about 75 mg in a cup of black or green tea. NCCIH says to keep caffeine moderate in pregnancy and to ask your provider. LactMed reports fussiness, jitteriness and poor sleep in infants only with extremely high maternal caffeine, and says tea given directly to infants can interfere with iron absorption and cause anemia. The FDA quotes the Dietary Guidelines that caffeinated drinks should be avoided for children younger than age 2. Authoritative guidance 26 25 15 24
  • Iron. Polyphenols in tea cut iron absorption from a meal in a radio-iron study, but that study did not test green tea. A 2024 case report describes severe iron-deficiency anemia in a woman after about three months of moderate green tea. If you have low iron or anemia, ask a clinician about tea around meals. Human study 9 7
  • Medicines. NCCIH says high doses of green tea lowered blood levels of the heart medicine nadolol, green tea extract lowered levels of atorvastatin, and an NCCIH-funded study showed an interaction with raloxifene. One 1999 case report links very large amounts of green tea with weaker warfarin effect. Ask your pharmacist if you take any regular medicine. Authoritative guidance 25 21
  • Very hot drinks. IARC classed drinking very hot beverages as probably carcinogenic to humans (Group 2A) for oesophageal cancer and said it is the temperature, not the drink, that appears responsible. This applies to hot tea as to any other very hot drink; letting a cup cool is a sensible step. Authoritative guidance 23
Side effects 6
EffectHow oftenSeverity and recoveryEvidence
Caffeine effects (fast heartbeat, jitters, poor sleep, upset stomach)
Listed by the FDA as signs of too much caffeine from any source.
Depends on how much caffeine you take and how sensitive you are; no rate in the sources readmild to moderate
Reversible when caffeine is cut back
Authoritative guidance 24
Nausea, constipation, stomach discomfort and higher blood pressure (extract)
NCCIH lists these for green tea extract supplements.
No rate in the sources readmild
Reversible after stopping (not stated)
Authoritative guidance 25
Gut problems, raised liver enzymes, insomnia, raised blood pressure, skin reactions (extract)
Cochrane lists these as adverse effects of green tea extract in trials.
Not given in the abstractmild to moderate
Not given
Systematic review 5
Liver injury (mostly extract; rarely tea)
High-dose extract raised liver enzymes in trials (EFSA, abstract).
Uncommon; no rate foundsevere
Mostly recovery after stopping; some cases need transplant or are fatal
Case report 25 16 17 4
Lower iron absorption; anemia in a vulnerable person
Green tea was not tested in the radio-iron study.
One case reportmoderate to severe
Improved after changing tea habits
Case report 9 7
Fluoride intake from tea
Green tea averaged 1.37 mg/L in a scoping review, below black and brick tea; the risk discussed is mainly for children and heavy drinkers.
Depends on tea type, brewing time and local waternot stated
not stated
Food analysis 11 19
Liver

Liver injury linked to green tea is rare and mostly linked to concentrated extract capsules or tablets. LiverTox says extract, and more rarely very large amounts of tea, have been implicated in acute liver injury, including liver failure needing transplant or death. EFSA found raised liver enzymes with high-dose EGCG supplements in trials and noted rare liver injury after infusions, most probably an unusual individual reaction. A systematic review of 159 human studies found liver events came from concentrated, catechin-rich preparations taken in large single doses, not from brewed tea or extracts used in drinks or food. NCCIH says people with a specific immune-related gene variant seem especially susceptible, and a secondary analysis of a one-year extract trial found liver enzyme rises differed by gene variant. 16 4 8 17 2 25

How often. No rate in tea drinkers or extract users could be found in the sources read.

Monitoring. No monitoring advice was read from an agency. The Safety tab tells readers to stop extract and seek care if liver warning signs appear.

  • p24862489.

This is a safety connection. It is not evidence that Green Tea supports liver health.

Medicines and supplements 6
WithWhy it mattersImportanceEvidenceWhat to do
Warfarin
prescription
The case authors suggested vitamin K in the tea could counter warfarin; vitamin K was not measured.One 1999 case report: INR fell from 3.79 to 1.37 after about a week of half a gallon to a gallon of green tea a day, and rose to 2.55 after stopping. It cannot prove cause and the amount was very large.Case report Very low certainty 21Tell your prescriber about any big change in tea habits so your INR can be checked.
Nadolol (beta-blocker)
prescription
Not described in the source read.NCCIH says green tea at high doses reduced blood levels of nadolol and so its effectiveness.Authoritative guidance Low certainty 25Ask your pharmacist if you take nadolol.
Atorvastatin (cholesterol medicine)
prescription
Not described in the source read.NCCIH says green tea extract can reduce blood levels of atorvastatin. This is about the extract.Authoritative guidance Low certainty 25Ask your pharmacist before taking green tea extract with a statin.
Raloxifene (bone medicine)
prescription
Not described in the source read.NCCIH says a study it funded showed an interaction between green tea and raloxifene. Details were not given.Authoritative guidance Low certainty 25Ask your pharmacist.
Iron supplements and iron-poor diets
supplement
Tea polyphenols reduce iron absorption in general.A radio-iron study showed black tea and herb teas cut iron absorption; green tea was not tested, and one case report links moderate green tea with severe anemia.Human study Low certainty 9 7If you have low iron, ask a clinician about drinking tea away from meals. Whether that works was not tested in the sources read.
Other sources of caffeine
food
Caffeine adds up across coffee, other teas, energy drinks and some supplements.The FDA says its 400 mg figure is for all caffeine in a day.Authoritative guidance Moderate certainty 24 26Count all caffeine sources, especially in pregnancy.
Who should check first 6
SituationAdviceEvidence
PregnancyGreen tea is not banned in pregnancy, but it counts toward the daily caffeine limit. No source read covers green tea extract capsules in pregnancy, so ask a clinician before using them.Authoritative guidance 26 25
BreastfeedingLactMed reports infant fussiness and poor sleep only with extremely high maternal caffeine. No studies of green tea extract in breastfeeding were found.Authoritative guidance 15
Infants and young childrenDo not give tea to infants. LactMed says it can interfere with iron absorption and cause anemia. Avoid caffeinated drinks for children under 2 (FDA, quoting the Dietary Guidelines).Authoritative guidance 15 24
Liver disease or past liver injury from a supplementAsk a clinician before using green tea extract capsules or tablets, because of the liver injury reports. The sources read do not give a rule for brewed tea in liver disease.Precaution from liver reports 16 4
Low iron or anemiaAsk a clinician. Tea can lower iron absorption.Human study 9 7
Taking warfarin, nadolol, a statin or raloxifeneAsk your pharmacist or prescriber before changing how much green tea or extract you take.Authoritative guidance 21 25
Overdose, product quality and regulators

Summary. Brewed green tea has no safety concerns reported for adults (NCCIH). The main toxicity concern is the liver, linked to concentrated catechin-rich extract taken in large single doses.

Animal. The Hu systematic review says lab studies show the liver as target organ, strongly tied to dosing conditions such as a large single dose by gavage and fasting, and to total catechin and EGCG content.

Human doses studied. EFSA found that high-dose EGCG taken as a food supplement raised liver enzymes in trials (the threshold is in the opinion). The Minnesota Green Tea Trial gave a high-dose extract for 12 months.

High dose or long term signals. Liver enzyme rises with long high-dose extract use; differences by gene variant in one secondary analysis.

Overdose response. Not described in the sources read.

Genotoxicity. Not read.

Toxic or hazardous parts. Leaf is the part used; stems are also in tea (LactMed). No source read compared other parts.

Quality problems were looked up only for fluoride. Sources read gave no measured lead, cadmium, aluminium or pesticide values for green tea, so that is unknown here, not shown safe.

Fluoride. Tea leaves take up fluoride. A scoping review of 88 studies gave average levels of brick tea 4.78 mg/L, black tea 2.73, green tea 1.37, white tea 0.49 and herbal tea 0.17; longer brewing released more. A Canary Islands study found black and mixed teas could give children aged 4 to 8 a large share of the EFSA upper limit; the abstract did not give green tea. 11 19

Heavy metals and pesticides. Not found in the sources read for green tea. Not described is not proof of none.

Supplement quality. LactMed notes that dietary supplements are not pre-approved by the FDA and labelled and actual ingredients and amounts can differ. In the case report, lab analysis of the capsules found no contaminants but a very high EGCG level. 15 17

BodyActionDate
NCCIH (NIH) (United States)Says no safety concerns have been reported for green tea as a beverage in adults; lists extract side effects, rare liver injury, medicine interactions and a caffeine caution in pregnancy. Notes the FDA has approved a specific green tea extract ointment as a prescription drug for genital warts (a topical drug, not a drink or supplement). source2025-02
EFSA (European Union)Opinion on safety of green tea catechins: infusions prepared the traditional way are in general considered safe at EU intakes; rare liver injury after infusions; supplements providing 800 mg EGCG a day or more raised liver enzymes. source2018-04
EMA / HMPC (European Union)Has a final EU herbal monograph and assessment report for Camellia sinensis non fermentatum folium (green tea); EMA page lists the therapeutic area as "Fatigue and weakness". source2014-04-29 (monograph); 2022-09-26 (assessment addendum)
NICHD LactMed (United States)Notes caffeine-related infant fussiness only at extremely high maternal intake; tea directly to infants can cause anemia; no oral extract data in breastfeeding. source2006
NHS (United Kingdom)Pregnancy: no more than 200 mg of caffeine a day; about 75 mg in a cup of black or green tea. source2026-06-15
US FDA (United States)Caffeine consumer update: green tea 37 mg per 12 fl oz; 400 mg a day not generally associated with harm in most adults; lists signs of too much caffeine. source2024-08-28
IARC (WHO) (International)Very hot beverages probably carcinogenic to humans (Group 2A); temperature, not the drink, appears responsible. source2016-06-15
When to get medical help
  • Yellow skin or eyes, dark urine, pale stools, strong tiredness, itching or pain in the upper right belly while using green tea extract: stop it and get medical care now.
  • Chest pain, a racing or irregular heartbeat, fainting: call emergency services.
  • Black stools, unusual bruising or bleeding if you take warfarin: contact your prescriber or emergency services.
  • Very pale skin, breathlessness or marked tiredness in someone who drinks a lot of tea and has low iron: see a clinician.

Stop using the product and contact a clinician or emergency service. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

What is green tea?

Green tea is a drink made from the leaves of the tea plant, Camellia sinensis. The leaves are steamed or pan fried and dried but not fermented. Black and oolong tea come from the same plant but are fermented fully or partly. The drink contains caffeine, L-theanine and catechins.

25 31

Is green tea the same as green tea extract?

No. A cup of tea is a weak water extract. Capsules and tablets are concentrated catechins and have been linked to rare serious liver injury. NCCIH reports no safety concerns for the drink in adults. Do not carry safety or benefit results from one to the other.

25 4 8

Does green tea lower cholesterol or blood pressure?

Maybe slightly. A 2011 pooled analysis found small falls in total and LDL cholesterol, and a 2025 review of 36 trials found about 1 mmHg lower blood pressure, with big differences between trials. A 2020 review of short tea trials found no effect, and most trials mix drinks and extracts. Evidence is low.

22 18 10 6

Does green tea help you lose weight?

Not much. A Cochrane review of 12 to 13 week trials found almost no weight change outside Japan (-0.04 kg on average). Japanese trials varied and could not be pooled.

12

Does green tea prevent cancer?

This has not been shown. A Cochrane review of 142 studies found limited, inconsistent, low-certainty evidence. Trials used extract, and observational studies cannot prove cause.

5 25

Do people who drink green tea live longer?

In Japan, people who drank five or more cups a day had lower all-cause and heart death rates than those who drank less than one cup. This is an association and may reflect other habits. NCCIH says the heart link is seen in Asian but not Western groups.

1 25

Does green tea help focus, memory or mood?

A review of 21 mostly small studies reported better attention and memory and less anxiety, mainly from caffeine and L-theanine together. It mixes drinks, extracts and single compounds, so certainty is low. Observational data on dementia are mixed and very low certainty.

14 13

Does green tea help with diabetes?

A meta-analysis of 14 trials found no significant effect of green tea supplements on fasting glucose, insulin or HbA1c in people with type 2 diabetes. Talk to your doctor before changing diabetes care.

3

Can green tea hurt the liver?

The drink rarely does. NCCIH reports no safety concerns for the beverage in adults, and liver injury is mostly linked to extract capsules and tablets. EFSA noted rare cases after infusions, likely an individual reaction. LiverTox lists liver failure and transplant for extracts. Stop any extract and get medical care if you notice yellow skin or eyes or dark urine.

25 4 16 17 8

Is green tea safe in pregnancy, breastfeeding or for children?

Green tea has caffeine, so it counts toward your daily limit. The NHS says no more than 200 mg of caffeine a day in pregnancy and estimates about 75 mg in a cup of black or green tea. LactMed reports infant fussiness only at extremely high maternal caffeine and no anemia in breastfed babies from maternal tea. Do not give tea to infants, and the FDA quotes guidance to avoid caffeinated drinks for children under 2. No source read covers extract capsules in pregnancy, so ask a clinician.

26 15 24 25

Does green tea interact with medicines?

NCCIH says high doses of green tea lowered blood levels of nadolol and the extract lowered atorvastatin, and that a study showed an interaction with raloxifene. One 1999 case report links very large amounts of green tea with weaker warfarin effect. Ask your pharmacist or prescriber.

25 21

Does tea affect iron, and is very hot tea a problem?

Tea polyphenols lowered iron absorption from a meal in a lab study (green tea was not tested), and a 2024 case report links moderate green tea with severe iron-deficiency anemia. IARC classed very hot beverages as probably carcinogenic to the oesophagus; it is the temperature, not the tea, so let a cup cool.

9 7 23

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Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-25
Last substantive update
2026-10-25
How we research
We searched PubMed and read the abstracts of about 22 sources, read the NCCIH, FDA, NHS and EMA pages and the IARC press release, checked the plant name in GBIF and three compounds in PubChem, and looked for LiverTox and LactMed (summary records read; the full LiverTox page was not opened). Only abstracts were read for papers. Certainty ratings are the compiler's own reading. No funding statement was read for most papers, so industry links are not ruled out. No study is cited that we could not verify.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown. This page is information, not a recommendation to drink or take anything.
Sources 31

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. Abe SK, Saito E, Sawada N, et al. Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan. European Journal of Epidemiology. 2019. PMID 31392470. DOI 10.1007/s10654-019-00545-y. (abstract)
  2. Acosta L, Byham-Gray L, Kurzer M, et al. Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5-Diphospho-glucuronosyltransferase 1A4 Genotypes. Journal of Dietary Supplements. 2023. PMID 36178169. DOI 10.1080/19390211.2022.2128501. (abstract)
  3. Asbaghi O, Fouladvand F, Gonzalez MJ, et al. Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes & Metabolic Syndrome. 2021. PMID 33285391. DOI 10.1016/j.dsx.2020.11.004. (abstract)
  4. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Younes M, Aggett P, et al. Scientific opinion on the safety of green tea catechins. EFSA Journal. 2018. PMID 32625874. DOI 10.2903/j.efsa.2018.5239. (abstract)
  5. Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews. 2020. PMID 32118296. DOI 10.1002/14651858.CD005004.pub3. (abstract)
  6. Hartley L, Flowers N, Holmes J, et al. Green and black tea for the primary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews. 2013. PMID 23780706. DOI 10.1002/14651858.CD009934.pub2. (abstract)
  7. He Y, Chen J. Severe iron-deficiency anemia after short-term moderate consumption of green tea in woman: A rare case report. Heliyon. 2024. PMID 39263133. DOI 10.1016/j.heliyon.2024.e36666. (abstract)
  8. Hu J, Webster D, Cao J, et al. The safety of green tea and green tea extract consumption in adults - Results of a systematic review. Regulatory Toxicology and Pharmacology. 2018. PMID 29580974. DOI 10.1016/j.yrtph.2018.03.019. (abstract)
  9. Hurrell RF, Reddy M, Cook JD. Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages. British Journal of Nutrition. 1999. PMID 10999016. (abstract)
  10. Igho-Osagie E, Cara K, Wang D, et al. Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Nutrition. 2020. PMID 33188386. DOI 10.1093/jn/nxaa295. (abstract)
  11. Jayasingha H, Amarasooriya G, Rajapaksha N, et al. Fluoride in tea: accumulation, dietary exposure, and future strategies for risk mitigation in food safety; a scoping review. Critical Reviews in Food Science and Nutrition. 2025. PMID 40504749. DOI 10.1080/10408398.2025.2516756. (abstract)
  12. Jurgens TM, Whelan AM, Killian L, et al. Green tea for weight loss and weight maintenance in overweight or obese adults. Cochrane Database of Systematic Reviews. 2012. PMID 23235664. DOI 10.1002/14651858.CD008650.pub2. (abstract)
  13. Kakutani S, Watanabe H, Murayama N. Green Tea Intake and Risks for Dementia, Alzheimer's Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review. Nutrients. 2019. PMID 31137655. DOI 10.3390/nu11051165. (abstract)
  14. Mancini E, Beglinger C, Drewe J, et al. Green tea effects on cognition, mood and human brain function: A systematic review. Phytomedicine. 2017. PMID 28899506. DOI 10.1016/j.phymed.2017.07.008. (abstract)
  15. NICHD / NLM. Drugs and Lactation Database (LactMed): Green Tea. LactMed (NCBI Bookshelf). 2006. PMID 30000907. (abstract)
  16. NIDDK. LiverTox: Green Tea (Clinical and Research Information on Drug-Induced Liver Injury). LiverTox (NCBI Bookshelf). 2012. PMID 31643260. (abstract)
  17. Pillukat MH, Bester C, Hensel A, et al. Concentrated green tea extract induces severe acute hepatitis in a 63-year-old woman - a case report with pharmaceutical analysis. Journal of Ethnopharmacology. 2014. PMID 24862489. DOI 10.1016/j.jep.2014.05.015. (abstract)
  18. Rezaei M, Akhavan N, Fathi F, et al. Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials. Blood Pressure. 2025. PMID 40497293. DOI 10.1080/08037051.2025.2517122. (abstract)
  19. Rodriguez I, Burgos A, Rubio C, et al. Human exposure to fluoride from tea (Camellia sinensis) in a volcanic region - Canary Islands, Spain. Environmental Science and Pollution Research. 2020. PMID 32740848. DOI 10.1007/s11356-020-10319-9. (abstract)
  20. Saklar S, Ertas E, Ozdemir IS, et al. Effects of different brewing conditions on catechin content and sensory acceptance in Turkish green tea infusions. Journal of Food Science and Technology. 2015. PMID 26396411. DOI 10.1007/s13197-015-1746-y. (abstract)
  21. Taylor JR, Wilt VM. Probable antagonism of warfarin by green tea. Annals of Pharmacotherapy. 1999. PMID 10332534. DOI 10.1345/aph.18238. (abstract)
  22. Zheng XX, Xu YL, Li SH, et al. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. American Journal of Clinical Nutrition. 2011. PMID 21715508. DOI 10.3945/ajcn.110.010926. (abstract)
  23. n/a. IARC (WHO): Press release no. 244, coffee, mate and very hot beverages (15 June 2016). n/a. 2016. (full-text)
  24. n/a. FDA: Spilling the Beans: How Much Caffeine Is Too Much? (content current as of 28 Aug 2024). n/a. 2024. (full-text)
  25. n/a. NCCIH (NIH): Green Tea: Usefulness and Safety (last updated February 2025). n/a. 2025. (full-text)
  26. n/a. NHS (UK): Foods to avoid in pregnancy (page last reviewed 15 June 2026). n/a. 2026. (full-text)
  27. n/a. EMA: Camelliae sinensis non fermentatum folium (green tea), herbal medicinal product page. n/a. 2026. (abstract)
  28. n/a. PubChem: epigallocatechin gallate (CID 65064), formula C22H18O11. n/a. 2026. (full-text)
  29. n/a. PubChem: caffeine (CID 2519), formula C8H10N4O2. n/a. 2026. (full-text)
  30. n/a. PubChem: L-theanine (CID 439378), formula C7H14N2O3. n/a. 2026. (full-text)
  31. n/a. GBIF Backbone Taxonomy: Camellia sinensis (L.) Kuntze (usage key 3189635), retrieved 2026-10-25. n/a. 2026. (full-text)

Where to buy

Check the label first. Whatever you buy, look for these:

  • The herb is the first or only ingredient
  • Organic or lab-tested if that matters to you
  • Loose leaf or tea bags, and how long they have been stored
  • If you take medicines or are pregnant, ask a pharmacist about the herb first

Talk to a pharmacist or doctor before you start any supplement, especially if you take medicines. See the Safety tab for interactions.

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Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.