Holistic Remedies · Ingredient
6-gingerol
Formula: C17H26O4 · MW: 294.391 · Drug-likeness: 0.65
⚗️ Identity
Name
6-gingerol
Aliases / Synonyms
gingerol; 23513-14-6; [6]-Gingerol; (6)-Gingerol; (S)-(+)-[6]Gingerol; (S)-(6)-Gingerol; (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one; (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one; 1391-73-7
🧪 Chemistry
Molecular Weight
294.3910
LogP
3.2338
Drug-likeness
0.65
Oral Bioavailability
35.6390
H-Bond Acceptors
4
H-Bond Donors
2
Rotatable Bonds
10
🔗 External References
0
Clinical Trials
1
Meta-Analyses
12
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
CRD42022334940
Anticancer effects of gingerol, shogaol and curcumin in cervical cancer: A systemic review.
📚 Sample References
PMID 32512025
6-Gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer in mice
Food Chem Toxicol · 2020
PMID 32720790
6-Gingerol protects cardiomyocytes against hypoxia-induced injury by regulating the KCNQ1OT1/miR-340-5p/PI3K/AKT pathway
Panminerva Med · 2021
PMID 33281606
The Inhibitory Effect of 6-Gingerol on Ubiquitin-Specific Peptidase 14 Enhances Autophagy-Dependent Ferroptosis and Anti-Tumor in vivo and in vitro
Front Pharmacol · 2020
PMID 33462378
6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway
Acta Pharmacol Sin · 2021
PMID 33670981
6-Gingerol, a Bioactive Compound of Ginger Attenuates Renal Damage in Streptozotocin-Induced Diabetic Rats by Regulating the Oxidative Stress and Inflammation
Pharmaceutics · 2021
PMID 33925065
Potential Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells
Int J Mol Sci · 2021