Holistic Remedies · Ingredient
Alpinetin
Formula: C16H14O4 · MW: 270.284 · Drug-likeness: 0.911
⚗️ Identity
Name
Alpinetin
Aliases / Synonyms
36052-37-6; (S)-7-Hydroxy-5-methoxy-2-phenylchroman-4-one; (-)-alpinetin; (S)-7-Hydroxy-5-methoxyflavanone; 5-O-Methylpinocembrin; Alpinetin, (S)-; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-; (2S)-7-hydroxy-5-methoxy-2-phenyl-2,3-dihydrochromen-4-one; SX3EL59QD8
🧪 Chemistry
Molecular Weight
270.2840
LogP
3.1073
Drug-likeness
0.911
H-Bond Acceptors
4
H-Bond Donors
1
Rotatable Bonds
2
🔗 External References
0
Clinical Trials
0
Meta-Analyses
8
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 30166541
Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation
Cell Death Dis · 2018
PMID 32372959
Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease
Front Pharmacol · 2020
PMID 32562470
Alpinetin inhibits breast cancer growth by ROS/NF-κB/HIF-1α axis
J Cell Mol Med · 2020
PMID 34093209
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ
Front Pharmacol · 2021
PMID 35988868
Alpinetin ameliorates bone loss in LPS-induced inflammation osteolysis via ROS mediated P38/PI3K signaling pathway
Pharmacol Res · 2022
PMID 36078140
Alpinetin Suppresses Effects of TGF-β1 on Stimulating the Production and Organization of Fibrotic Markers in Human Primary Dermal Fibroblasts
Cells · 2022