Holistic Remedies · Ingredient
Astaxanthin
Formula: C40H52O4 · MW: 596.8520000000002 · Drug-likeness: 0.247
⚗️ Identity
Name
Astaxanthin
Aliases / Synonyms
472-61-7; Ovoester; Astaxanthine; 3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione; all-trans-Astaxanthin; BioAstin; (3S,3'S)-Astaxanthin; AstaREAL; Natupink
🧪 Chemistry
Molecular Weight
596.8520
LogP
8.9054
Drug-likeness
0.247
H-Bond Acceptors
4
H-Bond Donors
2
Rotatable Bonds
10
🔗 External References
18
Clinical Trials
9
Meta-Analyses
40
PubMed References
Top Conditions Studied with Astaxanthin
Osteoarthritis, Knee 2
PCOS 1
Ageing|Photo-aging 1
Risk factors of metabolic syndrome, type 2 diabetes mellitus 1
Painful Diabetic Neuropathy 1
Absorption; Chemicals 1
Hypertension (HTN) is the common modifiable risk factor for 1
Effect of astaxanthin supplementation on plasma metabolites, 1
Metabolic Syndrome X 1
Cognitive impairment, reported subjectively and/ or objectiv 1
Metabolic Flexibility 1
Astaxanthin, extracted from Haematococcus pluvialis (H. pluv 1
📋 Sample Trials
NCT02343497
Lipid-lowering Effects of an Astaxanthin Supplement in Volunteers With Mild Dyslipidaemia
Completed · Dyslipidemias
NCT02397811
Astaxanthin Formulation Bioavailability
Completed · Bioavailability of Astaxanthin Formulati
NCT03460860
Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging
Completed · Skin Aging|Wrinkles
NCT03664466
Astaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory Indicators
Withdrawn · Osteoarthritis, Knee
NCT03991286
The Effect of Astaxanthin on Oxidative Stress Indices in Patients With Polycystic Ovary Syndrome
Completed · PCOS
NCT04689984
The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient
Unknown · Phase 2|Phase 3 · Painful Diabetic Neuropathy
📊 Sample Meta-Analyses
CRD42020215881
A systematic review of astaxanthin on the risk factors of metabolic syndrome
Risk factors of metabolic syndrome, type 2 diabetes mellitus
CRD42021275708
Impact of Astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials
Hypertension (HTN) is the common modifiable risk factor for cardiovascular disea
CRD42022335796
Efficacy of astaxanthin in animal models of type 2 diabetes mellitus: a systematic review and meta-analysis
CRD42022356955
Efficacy of astaxanthin supplementary on subjective fatigue, exercise performance, and cognitive function: A meta-analysis of randomizedcontrolled trials
Astaxanthin, extracted from Haematococcus pluvialis (H. pluvialis), is a natural
CRD42023428043
The effects of astaxanthin supplementation on liver enzymes levels: A systematic review and meta-analysis of randomized controlled trials
Astaxanthin belongs to a group of carotenoids that are oxidized (1-3). It is a n
CRD42023409269
The effect of Astaxanthin intake on cardio-metabolic risk factors, Inflammatory, and liver enzymes: a systematic review and meta-analysis
unhealthy adults with metabolic syndrome and related diseases
📚 Sample References
PMID 32003547
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
J Cachexia Sarcopenia Muscle · 2020
PMID 32082151
Preventive and Therapeutic Effects of Astaxanthin on Depressive-Like Behaviors in High-Fat Diet and Streptozotocin-Treated Rats
Front Pharmacol · 2020
PMID 32210012
Astaxanthin Prevents Mitochondrial Impairment Induced by Isoproterenol in Isolated Rat Heart Mitochondria
Antioxidants (Basel) · 2020
PMID 32351673
Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction
Oxid Med Cell Longev · 2020
PMID 32405635
Astaxanthin from Haematococcus pluvialis ameliorates the chemotherapeutic drug (doxorubicin) induced liver injury through the Keap1/Nrf2/HO-1 pathway in mice
Food Funct · 2020
PMID 32438569
Astaxanthin Modulates Apoptotic Molecules to Induce Death of SKBR3 Breast Cancer Cells
Mar Drugs · 2020
🏥 Linked Health Topics 4 · matched via study conditions
Related
Functional Action
- Antioxidant · score 80
- Muscle Recovery · score 40
Wellness Goal
- Healthy Skin · score 60
- Muscle Recovery · score 40
Body System
- Skin, Hair & Beauty · score 60
- Integumentary System · score 60
Root Cause
- Oxidative Stress · score 60