Holistic Remedies · Ingredient
Cafestol
Formula: C20H28O3 · MW: 316.441 · Drug-likeness: 0.831
⚗️ Identity
Name
Cafestol
Aliases / Synonyms
469-83-0; cafesterol; CCRIS 1518; UNII-AC465T6Q6W; (-)-cafestol; AC465T6Q6W; CHEBI:3291; CAFESTOL [MI]; DTXSID3040986
🧪 Chemistry
Molecular Weight
316.4410
LogP
3.6393
Drug-likeness
0.831
H-Bond Acceptors
3
H-Bond Donors
2
Rotatable Bonds
1
🔗 External References
3
Clinical Trials
0
Meta-Analyses
2
PubMed References
Top Conditions Studied with Cafestol
📋 Sample Trials
NCT04908904
Acute Effects of Cafestol on Glucose Metabolism in Subjects With Type-2-diabetes.
Completed · Diabetes Mellitus, Type 2
NCT04911582
Does the Bioactive Substance in Coffee, Cafestol, Have Preventive Properties on Type-2-diabetes? (Acute Substudy)
Completed · Obesity, Abdominal
NCT05672433
Long-term Metabolic Effects of Cafestol
Unknown · Obesity, Abdominal
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 25375379
Cafestol overcomes ABT-737 resistance in Mcl-1-overexpressed renal carcinoma Caki cells through downregulation of Mcl-1 expression and upregulation of Bim expression
Cell Death Dis · 2014
PMID 22734486
Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesothelioma
J Biomed Sci · 2012
🏥 Linked Health Topics 1 · matched via study conditions