Holistic Remedies · Ingredient
Cinnamaldehyde
Formula: C9H8O · MW: 132.1619999999999 · Drug-likeness: 0.443
⚗️ Identity
Name
Cinnamaldehyde
Aliases / Synonyms
trans-Cinnamaldehyde; 14371-10-9; 104-55-2; Cinnamic aldehyde; (E)-Cinnamaldehyde; 3-Phenylacrylaldehyde; Cinnamal; Zimtaldehyde; 2-Propenal, 3-phenyl-
🧪 Chemistry
Molecular Weight
132.1620
LogP
1.8987
Drug-likeness
0.443
Oral Bioavailability
31.9900
H-Bond Acceptors
1
Rotatable Bonds
2
🔗 External References
HERB DB
PubChem CID
CAS Number
InChIKey
KJPRLNWUNMBNBZ-QPJJXVBHSA-N
2
Clinical Trials
1
Meta-Analyses
20
PubMed References
Top Conditions Studied with Cinnamaldehyde
📋 Sample Trials
NCT01667523
The Effect of Capsaicin and Cinnamaldehyde on Intestinal Permeability
Completed · Healthy
NCT04415892
The Role of TRP Channels in CIPN
Recruiting · Chemotherapy-induced Peripheral Neuropat
📊 Sample Meta-Analyses
CRD42020166373
Effects of Cinnamaldehyde on Anti-Respiratory Syncytial Virus: a protocol of systematic review and meta-analysis
cinnamaldehyde; anti-Respiratory Syncytial Virus
📚 Sample References
PMID 31376499
Trans-cinnamaldehyde improves neuroinflammation-mediated NMDA receptor dysfunction and memory deficits through blocking NF-κB pathway in presenilin1/2 conditional double knockout mice
Brain Behav Immun · 2019
PMID 31504241
CGRP derived from cardiac fibroblasts is an endogenous suppressor of cardiac fibrosis
Cardiovasc Res · 2019
PMID 30831189
Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice
Free Radic Biol Med · 2019
PMID 30239332
Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke
Elife · 2018
PMID 29046261
Cinnamaldehyde induces fat cell-autonomous thermogenesis and metabolic reprogramming
Metabolism · 2017
PMID 27838370
Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production
J Mol Cell Cardiol · 2016