Holistic Remedies · Ingredient
Dialls2
Formula: C6H10S2 · MW: 146.28 · Drug-likeness: 0.332
⚗️ Identity
Name
Dialls2
Aliases / Synonyms
DIALLYL DISULFIDE; 2179-57-9; Allyl disulfide; Diallyldisulfide; Diallyl disulphide; 1,2-Diallyldisulfane; Disulfide, di-2-propenyl; Allyl disulphide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene
🧪 Chemistry
Molecular Weight
146.2800
LogP
2.7398
Drug-likeness
0.332
Oral Bioavailability
49.2830
H-Bond Acceptors
2
Rotatable Bonds
5
🔗 External References
0
Clinical Trials
0
Meta-Analyses
6
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32124958
Diallyl disulfide induces downregulation and inactivation of cofilin 1 differentiation via the Rac1/ROCK1/LIMK1 pathway in leukemia cells
Int J Oncol · 2020
PMID 32135404
Identification of a pro-elongation effect of diallyl disulfide, a major organosulfur compound in garlic oil, on microglial process
J Nutr Biochem · 2020
PMID 34356307
The Anxiolytic and Antidepressant Effects of Diallyl Disulfide and GYY4137 in Animals with Chronic Neuropathic Pain
Antioxidants (Basel) · 2021
PMID 34896185
Diallyl disulfide suppresses the lipopolysaccharide-driven inflammatory response of macrophages by activating the Nrf2 pathway
Food Chem Toxicol · 2022
PMID 35120919
Dual regulating of mitochondrial fusion and Timp-3 by leflunomide and diallyl disulfide combination suppresses diethylnitrosamine-induced hepatocellular tumorigenesis in rats
Life Sci · 2022
PMID 35690339
Insight into drug sensitizing effect of diallyl disulfide and diallyl trisulfide from Allium sativum L. on paclitaxel-resistant triple-negative breast cancer cells
J Ethnopharmacol · 2022