Holistic Remedies · Ingredient
Embelin
Formula: C17H26O4 · MW: 294.391 · Drug-likeness: 0.465
⚗️ Identity
Name
Embelin
Aliases / Synonyms
550-24-3; Embelic acid; 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione; Emberine; 2,5-Dihydroxy-3-undecyl-1,4-benzoquinone; 2,5-Dihydroxy-3-undecyl-p-benzoquinone; 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione; CHEBI:4778; Potassium embelate
🧪 Chemistry
Molecular Weight
294.3910
LogP
4.3131
Drug-likeness
0.465
Oral Bioavailability
37.7180
H-Bond Acceptors
4
H-Bond Donors
2
Rotatable Bonds
10
🔗 External References
0
Clinical Trials
0
Meta-Analyses
6
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 30377563
Embelin impairs the accumulation and activation of MDSCs in colitis-associated tumorigenesis
Oncoimmunology · 2018
PMID 29471103
Embelin and its derivatives unravel the signaling, proinflammatory and antiatherogenic properties of GPR84 receptor
Pharmacol Res · 2018
PMID 29170254
WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia
Haematologica · 2018
PMID 25128650
Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells
Cancer Lett · 2014
PMID 21709246
miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia
Proc Natl Acad Sci U S A · 2011
PMID 21565443
Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN
Cancer Lett · 2011