natural remedies · Ingredient
Ergothioneine
Formula: C9H15N3O2S · MW: 229.305 · Drug-likeness: 0.537
⚗️ Identity
Name
Ergothioneine
Aliases / Synonyms
497-30-3; L-(+)-Ergothioneine; L-Ergothioneine; Sympectothion; Ergothionine; Thioneine; l-Thioneine; Thiolhistidine-betaine; L(+)-Ergothioneine
🧪 Chemistry
Molecular Weight
229.3050
LogP
-0.5605
Drug-likeness
0.537
H-Bond Acceptors
3
H-Bond Donors
2
Rotatable Bonds
4
🔗 External References
1
Clinical Trials
0
Meta-Analyses
3
PubMed References
Top Conditions Studied with Ergothioneine
📋 Sample Trials
NCT05190432
Taxifolin/Ergothioneine and Immune Biomarkers in Healthy Volunteers (TaxEr)
Active_Not_Recruiting · Antioxidative Stress|Cold|Influenza|Agin
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 27101740
Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6
Free Radic Biol Med · 2016
PMID 32104530
The Antiaging Activity of Ergothioneine in UVA-Irradiated Human Dermal Fibroblasts via the Inhibition of the AP-1 Pathway and the Activation of Nrf2-Mediated Antioxidant Genes
Oxid Med Cell Longev · 2020
PMID 33964294
Ergothioneine mitigates cisplatin-evoked nephrotoxicity via targeting Nrf2, NF-κB, and apoptotic signaling and inhibiting γ-glutamyl transpeptidase
Life Sci · 2021