natural remedies · Ingredient
Eriodictyol
Formula: C15H12O6 · MW: 288.255 · Drug-likeness: 0.599
⚗️ Identity
Name
Eriodictyol
Aliases / Synonyms
552-58-9; Eriodictiol; (+)-Eriodictyol; Huazhongilexone; (S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one; UNII-Q520486B8Y; CHEBI:28412; (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
🧪 Chemistry
Molecular Weight
288.2550
LogP
2.2155
Drug-likeness
0.599
Oral Bioavailability
71.7930
H-Bond Acceptors
6
H-Bond Donors
4
Rotatable Bonds
1
🔗 External References
0
Clinical Trials
0
Meta-Analyses
4
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32158391
Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway
Front Pharmacol · 2020
PMID 34785489
Eriodictyol protects skin cells from UVA irradiation-induced photodamage by inhibition of the MAPK signaling pathway
J Photochem Photobiol B · 2022
PMID 35093024
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation
Mol Med · 2022
PMID 35184647
Eriodictyol suppresses the malignant progression of colorectal cancer by downregulating tissue specific transplantation antigen P35B (TSTA3) expression to restrain fucosylation
Bioengineered · 2022
🔗 Knowledge Graph Connections
Open full graph →Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 22 related entities shown — click any to follow the trail.
🌿 Herbs containing this compound · 1
🧬 Gene targets · 9
Prostaglandin G/H synthase 2
binding 0.877
Heat shock protein HSP 90
binding 0.849
mRNA of PKA Catalytic Subunit C-alpha
binding 0.820
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform
binding 0.815
NCOA2
NCOA2
binding 0.812
Prostaglandin G/H synthase 1
binding 0.808
HMOX1
HMOX1
NAD(P)H dehydrogenase [quinone] 1
Nuclear factor erythroid 2-related factor 2
🏥 Linked health topics · 12
Abdominal aortic aneurysm
disease
Adenomatous polyposis
disease
Alzheimer'S Disease
syndrome
Analgesics
disease
Angioedema
phenotype
Arthritis
syndrome
Bladder cancer
disease
Breast cancer
disease
Cancer, unspecific
disease
Carcinoma in situ, unspecified
disease
Cardiovascular disease, unspecified
disease
Carpal Tunnel Syndrome
syndrome